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A 4-aminobenzoic acid derivative as novel lead for selective inhibitors of multidrug resistance-associated proteins

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (17), p.4761-4763

2008

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4-Hydroxyacetophenone-induced choleresis in rats is mediated by the Mrp2-Dependent biliary secretion of its glucuronide conjugate

Pharmaceutical research, 2006-11, Vol.23 (11), p.2603-2610

2006

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The ABC Transporters MDR1 and MRP2: Multiple Functions in Disposition of Xenobiotics and Drug Resistance

Drug metabolism reviews, 2004, Vol.36 (3-4), p.669-701

2004

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ABCC2 (1249G > A) polymorphism implicates altered transport activity for sorafenib

Xenobiotica, 2017-11, Vol.47 (11), p.1008-1014

2017

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ABCC2/Abcc2: a multispecific transporter with dominant excretory functions

Drug metabolism reviews, 2010-08, Vol.42 (3), p.402-436

2010

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ABCC2 expression in papillary renal cell carcinoma provides better prognostic stratification than WHO/ISUP nucleolar grade

Human pathology, 2022-02, Vol.120, p.57-70

2022

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ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds

Biochemical pharmacology, 2012-12, Vol.84 (12), p.1651-1659

2012

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Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo

Molecular cancer therapeutics, 2009-12, Vol.8 (12), p.3350-3359

2009

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Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum

Biochemical pharmacology, 2012-01, Vol.83 (2), p.279-285

2012

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Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry

Analytical biochemistry, 2008-09, Vol.380 (2), p.211-222

2008

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Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in De novo and relapsed acute myeloid leukemia

Leukemia, 2001-10, Vol.15 (10), p.1544-1553

2001

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An acute herb-drug interaction of Magnoliae Officinalis Cortex with methotrexate via inhibiting multidrug resistance-associated protein 2

Journal of Food and Drug Analysis, 2024-03, Vol.32 (1), p.103-117

2024

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Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-d-glucuronide in rat intestine and Caco-2 cells

Archives of toxicology, 2018-02, Vol.92 (2), p.777-788

2018

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Advancement of Structure-Activity Relationship of Multidrug Resistance-Associated Protein 2 Interactions

The AAPS journal, 2009-09, Vol.11 (3), p.406, Article 406

2009

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Alternative transporter pathways in patients with untreated early-stage and late-stage primary biliary cirrhosis

Liver international, 2009-03, Vol.29 (3), p.406-414

2009

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Antidepressant induced cholestasis: hepatocellular redistribution of multidrug resistant protein (MRP2)

Gut, 2003-02, Vol.52 (2), p.300-303

2003

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Application of quantitative time-lapse imaging (QTLI) for evaluation of Mrp2-based drug–drug interaction induced by liver metabolites

Toxicology and applied pharmacology, 2012-09, Vol.263 (2), p.244-250

2012

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Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?

Pharmaceutical research, 2002-06, Vol.19 (6), p.773-779

2002

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ARID1A ablation leads to multiple drug resistance in ovarian cancer via transcriptional activation of MRP2

Cancer letters, 2018-07, Vol.427, p.9-17

2018

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Aristolochic acid I is a substrate of BCRP but not P-glycoprotein or MRP2

Journal of ethnopharmacology, 2015-08, Vol.172, p.430-435

2015

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Arsenic–glutathione conjugate transport by the human multidrug resistance proteins (MRPs/ABCCs)

Journal of inorganic biochemistry, 2012-03, Vol.108, p.141-149

Leslie, Elaine M.

2012

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Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules

Biological chemistry, 2019-09, Vol.400 (10), p.1335-1345

2019

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Assessment and modulation of forsythiaside absorption with MDCKII cells and validation with in situ intestinal experiment

European journal of drug metabolism and pharmacokinetics, 2012-09, Vol.37 (3), p.179-186

2012

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Association of the multidrug-resistance-associated protein gene ( ABCC2 ) variants with intrahepatic cholestasis of pregnancy

Journal of hepatology, 2008-01, Vol.48 (1), p.125-132

2008

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The association of transporter ABCC2 (MRP2) genetic variation and drug-induced hyperbilirubinemia

Journal of the Chinese Medical Association, 2021-02, Vol.84 (2), p.129-135

2021

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A 4-aminobenzoic acid derivative as novel lead for selective inhibitors of multidrug resistance-associated proteins

4-Hydroxyacetophenone-induced choleresis in rats is mediated by the Mrp2-Dependent biliary secretion of its glucuronide conjugate

The ABC Transporters MDR1 and MRP2: Multiple Functions in Disposition of Xenobiotics and Drug Resistance

ABCC2 (1249G > A) polymorphism implicates altered transport activity for sorafenib

ABCC2/Abcc2: a multispecific transporter with dominant excretory functions

ABCC2 expression in papillary renal cell carcinoma provides better prognostic stratification than WHO/ISUP nucleolar grade

ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds

Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo

Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum

Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry

Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in De novo and relapsed acute myeloid leukemia

An acute herb-drug interaction of Magnoliae Officinalis Cortex with methotrexate via inhibiting multidrug resistance-associated protein 2

Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-d-glucuronide in rat intestine and Caco-2 cells

Advancement of Structure-Activity Relationship of Multidrug Resistance-Associated Protein 2 Interactions

Alternative transporter pathways in patients with untreated early-stage and late-stage primary biliary cirrhosis

Antidepressant induced cholestasis: hepatocellular redistribution of multidrug resistant protein (MRP2)

Application of quantitative time-lapse imaging (QTLI) for evaluation of Mrp2-based drug–drug interaction induced by liver metabolites

Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?

ARID1A ablation leads to multiple drug resistance in ovarian cancer via transcriptional activation of MRP2

Aristolochic acid I is a substrate of BCRP but not P-glycoprotein or MRP2

Arsenic–glutathione conjugate transport by the human multidrug resistance proteins (MRPs/ABCCs)

Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules

Assessment and modulation of forsythiaside absorption with MDCKII cells and validation with in situ intestinal experiment

Association of the multidrug-resistance-associated protein gene ( ABCC2 ) variants with intrahepatic cholestasis of pregnancy

The association of transporter ABCC2 (MRP2) genetic variation and drug-induced hyperbilirubinemia

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