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Regenerating gene (REG) product and its potential clinical usage

Expert opinion on therapeutic targets, 2016-05, Vol.20 (5), p.541-550

Takasawa, Shin

2016

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METTL14 is essential for β-cell survival and insulin secretion

Biochimica et biophysica acta. Molecular basis of disease, 2019-09, Vol.1865 (9), p.2138-2148

2019

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Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma

Oncotarget, 2016-11, Vol.7 (47), p.77838-77853

2016

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Reg family proteins contribute to inflammation and pancreatic stellate cells activation in chronic pancreatitis

Scientific reports, 2023-07, Vol.13 (1), p.12201-12201, Article 12201

2023

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Serial monitoring of pancreatic stone protein for the detection of sepsis in intensive care unit patients with complicated abdominal surgery: A prospective, longitudinal cohort study

Journal of critical care, 2024-08, Vol.82, p.154772, Article 154772

2024

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MicroRNA-7 directly targets Reg1 in pancreatic cells

American Journal of Physiology: Cell Physiology, 2019-08, Vol.317 (2), p.C366-C374

2019

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Knockdown of REG Iα Enhances the Sensitivity to 5-Fluorouracil of Colorectal Cancer Cells via Cyclin D1/CDK4 Pathway and BAX/BCL-2 Pathways

Cancer biotherapy & radiopharmaceuticals, 2019-08, Vol.34 (6), p.362

2019

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Measurement of pancreatic stone protein in the identification and management of sepsis

Biomarkers in medicine, 2019-02, Vol.13 (2), p.135-145

2019

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Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma

Clinical cancer research, 2015-08, Vol.21 (15), p.3512-3521

2015

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Pancreatic Stone Protein Predicts Sepsis in Severely Burned Patients Irrespective of Trauma Severity: A Monocentric Observational Study

Annals of surgery, 2021-12, Vol.274 (6), p.e1179

2021

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The role of pancreatic stone protein as a prognostic factor for COVID-19 patients

European review for medical and pharmacological sciences, 2022-09, Vol.26 (17), p.6391

2022

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Expression of Reg family genes in the gastrointestinal tract of mice treated with indomethacin

American journal of physiology: Gastrointestinal and liver physiology, 2015-05, Vol.308 (9), p.G736-G744

2015

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Involvement of autoimmunity to REG, a regeneration factor, in patients with primary Sjögren's syndrome

Clinical and experimental immunology, 2013-10, Vol.174 (1), p.1-9

2013

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Research advances on application of pancreatic stone protein in the early diagnosis of sepsis

Zhonghua shao shang yu chuang mian xiu fu za zhi, 2023-10, Vol.39 (10), p.985

2023

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The Gut Epithelial Receptor LRRC19 Promotes the Recruitment of Immune Cells and Gut Inflammation

Cell reports (Cambridge), 2016-02, Vol.14 (4), p.695-707

2016

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Regenerating Islet-derived 1α (Reg-1α) Protein Is New Neuronal Secreted Factor That Stimulates Neurite Outgrowth via Exostosin Tumor-like 3 (EXTL3) Receptor

The Journal of biological chemistry, 2012-02, Vol.287 (7), p.4726-4739

2012

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REG1B as a predictor of childhood stunting in Bangladesh and Peru

The American journal of clinical nutrition, 2013-05, Vol.97 (5), p.1129-1133

2013

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Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer

Cancer cell, 2013-03, Vol.23 (3), p.406-420

2013

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Bacterially-Associated Transcriptional Remodelling in a Distinct Genomic Subtype of Colorectal Cancer Provides a Plausible Molecular Basis for Disease Development

PloS one, 2016-11, Vol.11 (11), p.e0166282-e0166282

2016

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REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation

Cell and tissue research, 2013-06, Vol.352 (3), p.639-646

2013

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Crucial role of Reg I from acinar-like cell cluster touching with islets (ATLANTIS) on mitogenesis of beta cells in EMC virus-induced diabetic mice

Biochemical and biophysical research communications, 2018-09, Vol.503 (2), p.963-969

2018

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Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells

Scientific reports, 2019-03, Vol.9 (1), p.5199, Article 5199

2019

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Linking gene expression to clinical outcomes in pediatric Crohn's disease using machine learning

Scientific reports, 2024-02, Vol.14 (1), p.2667-2667, Article 2667

2024

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Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip

American journal of physiology: Gastrointestinal and liver physiology, 2021-03, Vol.320 (3), p.G258-G271

2021

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Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation

Scientific reports, 2018-01, Vol.8 (1), p.624-15, Article 624

2018

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Regenerating gene (REG) product and its potential clinical usage

METTL14 is essential for β-cell survival and insulin secretion

Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma

Reg family proteins contribute to inflammation and pancreatic stellate cells activation in chronic pancreatitis

Serial monitoring of pancreatic stone protein for the detection of sepsis in intensive care unit patients with complicated abdominal surgery: A prospective, longitudinal cohort study

MicroRNA-7 directly targets Reg1 in pancreatic cells

Knockdown of REG Iα Enhances the Sensitivity to 5-Fluorouracil of Colorectal Cancer Cells via Cyclin D1/CDK4 Pathway and BAX/BCL-2 Pathways

Measurement of pancreatic stone protein in the identification and management of sepsis

Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma

Pancreatic Stone Protein Predicts Sepsis in Severely Burned Patients Irrespective of Trauma Severity: A Monocentric Observational Study

The role of pancreatic stone protein as a prognostic factor for COVID-19 patients

Expression of Reg family genes in the gastrointestinal tract of mice treated with indomethacin

Involvement of autoimmunity to REG, a regeneration factor, in patients with primary Sjögren's syndrome

Research advances on application of pancreatic stone protein in the early diagnosis of sepsis

The Gut Epithelial Receptor LRRC19 Promotes the Recruitment of Immune Cells and Gut Inflammation

Regenerating Islet-derived 1α (Reg-1α) Protein Is New Neuronal Secreted Factor That Stimulates Neurite Outgrowth via Exostosin Tumor-like 3 (EXTL3) Receptor

REG1B as a predictor of childhood stunting in Bangladesh and Peru

Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer

Bacterially-Associated Transcriptional Remodelling in a Distinct Genomic Subtype of Colorectal Cancer Provides a Plausible Molecular Basis for Disease Development

REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation

Crucial role of Reg I from acinar-like cell cluster touching with islets (ATLANTIS) on mitogenesis of beta cells in EMC virus-induced diabetic mice

Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells

Linking gene expression to clinical outcomes in pediatric Crohn's disease using machine learning

Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip

Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation

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