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Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism

Nature communications, 2019-10, Vol.10 (1), p.4971-17, Article 4971

2019

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Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

Nature (London), 2020-03, Vol.579 (7800), p.586-591

2020

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Unraveling the Regulation of Hepatic Metabolism by Insulin

Trends in endocrinology and metabolism, 2017-07, Vol.28 (7), p.497-505

2017

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Fructose- and sucrose- but not glucose-sweetened beverages promote hepatic de novo lipogenesis: A randomized controlled trial

Journal of hepatology, 2021-07, Vol.75 (1), p.46-54

2021

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Reprogramming of fatty acid metabolism in cancer

British journal of cancer, 2020-01, Vol.122 (1), p.4-22

2020

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Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production

Cell metabolism, 2016-06, Vol.23 (6), p.1154-1166

2016

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De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

Nature medicine, 2014-11, Vol.20 (11), p.1327-1333

2014

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Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence

Nature (London), 2018-01, Vol.553 (7688), p.351-355

2018

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Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE (-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis

International journal of molecular sciences, 2021-01, Vol.22 (2), p.818

2021

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Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

Nature communications, 2019-02, Vol.10 (1), p.623-13, Article 623

2019

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Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice

Endocrinology (Philadelphia), 2016-03, Vol.157 (3), p.1029-1042

2016

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Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis

Clinical cancer research, 2016-11, Vol.22 (21), p.5337-5348

2016

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Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.E7158-E7165

2018

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Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells

European journal of pharmacology, 2019-10, Vol.861, p.172618-172618, Article 172618

2019

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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

The Journal of clinical investigation, 2017-11, Vol.127 (11), p.4059-4074

2017

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Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes

PloS one, 2012-01, Vol.7 (1), p.e28784

2012

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miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression

Gut, 2018-06, Vol.67 (6), p.1124

2018

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Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis

Nature communications, 2019-07, Vol.10 (1), p.2987-16, Article 2987

2019

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Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production

Nature communications, 2014-01, Vol.5 (1), p.3131-3131, Article 3131

2014

Volltextzugriff (PDF)

Poria cocus Wolf Extract Ameliorates Hepatic Steatosis through Regulation of Lipid Metabolism, Inhibition of ER Stress, and Activation of Autophagy via AMPK Activation

International journal of molecular sciences, 2019-09, Vol.20 (19), p.4801

2019

Volltextzugriff (PDF)

Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat

The journal of clinical endocrinology and metabolism, 2015-06, Vol.100 (6), p.2434-2442

2015

Volltextzugriff (PDF)

GS-0976 (Firsocostat): an investigational liver-directed acetyl-CoA carboxylase (ACC) inhibitor for the treatment of non-alcoholic steatohepatitis (NASH)

Expert opinion on investigational drugs, 2020-02, Vol.29 (2), p.135-141

2020

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Fatty Acid Synthase–Suppressor Screening Identifies Sorting Nexin 8 as a Therapeutic Target for NAFLD

Hepatology (Baltimore, Md.), 2021-11, Vol.74 (5), p.2508-2525

2021

Volltextzugriff (PDF)

De novo lipogenesis in health and disease

Metabolism, clinical and experimental, 2014-07, Vol.63 (7), p.895-902

2014

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Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis

European journal of pharmacology, 2021-09, Vol.906, p.174280-174280, Article 174280

2021

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Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

Unraveling the Regulation of Hepatic Metabolism by Insulin

Fructose- and sucrose- but not glucose-sweetened beverages promote hepatic de novo lipogenesis: A randomized controlled trial

Reprogramming of fatty acid metabolism in cancer

Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence

Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE (-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice

Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis

Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication

Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes

miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis

Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production

Poria cocus Wolf Extract Ameliorates Hepatic Steatosis through Regulation of Lipid Metabolism, Inhibition of ER Stress, and Activation of Autophagy via AMPK Activation

Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat

GS-0976 (Firsocostat): an investigational liver-directed acetyl-CoA carboxylase (ACC) inhibitor for the treatment of non-alcoholic steatohepatitis (NASH)

Fatty Acid Synthase–Suppressor Screening Identifies Sorting Nexin 8 as a Therapeutic Target for NAFLD

De novo lipogenesis in health and disease

Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis

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