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Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex

Nature (London), 2019-04, Vol.568 (7750), p.127-130

2019

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Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

Nature immunology, 2013-05, Vol.14 (5), p.500

2013

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The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)

The Journal of biological chemistry, 2018-02, Vol.293 (8), p.2877-2887

2018

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Single cell analysis of kynurenine and System L amino acid transport in T cells

Nature communications, 2018-05, Vol.9 (1), p.1981-11, Article 1981

2018

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Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma

Cellular and molecular life sciences : CMLS, 2021-01, Vol.78 (1), p.195-206

2021

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Reevaluating the Substrate Specificity of the L‑Type Amino Acid Transporter (LAT1)

Journal of medicinal chemistry, 2018-08, Vol.61 (16), p.7358-7373

2018

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Large neutral amino acid levels tune perinatal neuronal excitability and survival

Cell, 2023-04, Vol.186 (9), p.1950-1967.e25

2023

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The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation

The Journal of cell biology, 2014-07, Vol.206 (2), p.173-182

2014

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LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter

The international journal of biochemistry & cell biology, 2015-10, Vol.67, p.25-33

2015

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MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

Genes & development, 2019-09, Vol.33 (17-18), p.1236-1251

2019

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mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

Molecular cell, 2019-10, Vol.76 (1), p.163-176.e8

2019

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Increases in circulating amino acids with in-feed antibiotics correlated with gene expression of intestinal amino acid transporters in piglets

Amino acids, 2017-09, Vol.49 (9), p.1587-1599

2017

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L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy

Journal of pharmacological sciences, 2022-01, Vol.148 (1), p.31-40

2022

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Conditional inactivation of the L‐type amino acid transporter LAT1 in chondrocytes models idiopathic scoliosis in mice

Journal of cellular physiology, 2022-11, Vol.237 (11), p.4292-4302

2022

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The CD98 Heavy Chain Is a Marker and Regulator of Head and Neck Squamous Cell Carcinoma Radiosensitivity

Clinical cancer research, 2019-05, Vol.25 (10), p.3152-3163

2019

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Transport of Pregabalin Via L-Type Amino Acid Transporter 1 (SLC7A5) in Human Brain Capillary Endothelial Cell Line

Pharmaceutical research, 2018-12, Vol.35 (12), p.246-9, Article 246

2018

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Enhanced glutamine uptake influences composition of immune cell infiltrates in breast cancer

British journal of cancer, 2020-01, Vol.122 (1), p.94-101

2020

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Large Amino Acid Transporter 1 Selective Liposomes of l‑DOPA Functionalized Amphiphile for Combating Glioblastoma

Molecular pharmaceutics, 2017-11, Vol.14 (11), p.3834-3847

2017

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Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells

Journal of pharmacological sciences, 2024-05, Vol.155 (1), p.14-20

2024

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Effects of dietary n-6:n-3 PUFA ratio on fatty acid composition, free amino acid profile and gene expression of transporters in finishing pigs

British journal of nutrition, 2015-03, Vol.113 (5), p.739-748

2015

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Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1

PLoS genetics, 2015-10, Vol.11 (10), p.e1005624-e1005624

2015

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The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2

International journal of molecular sciences, 2020-10, Vol.21 (20), p.7573

2020

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LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells

The Journal of immunology (1950), 2013-10, Vol.191 (8), p.4080-4085

2013

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Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex

Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)

Single cell analysis of kynurenine and System L amino acid transport in T cells

Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma

Reevaluating the Substrate Specificity of the L‑Type Amino Acid Transporter (LAT1)

Large neutral amino acid levels tune perinatal neuronal excitability and survival

The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation

LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter

MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

Increases in circulating amino acids with in-feed antibiotics correlated with gene expression of intestinal amino acid transporters in piglets

L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy

Conditional inactivation of the L‐type amino acid transporter LAT1 in chondrocytes models idiopathic scoliosis in mice

The CD98 Heavy Chain Is a Marker and Regulator of Head and Neck Squamous Cell Carcinoma Radiosensitivity

Transport of Pregabalin Via L-Type Amino Acid Transporter 1 (SLC7A5) in Human Brain Capillary Endothelial Cell Line

Enhanced glutamine uptake influences composition of immune cell infiltrates in breast cancer

HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5

Large Amino Acid Transporter 1 Selective Liposomes of l‑DOPA Functionalized Amphiphile for Combating Glioblastoma

Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells

Effects of dietary n-6:n-3 PUFA ratio on fatty acid composition, free amino acid profile and gene expression of transporters in finishing pigs

Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1

The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2

LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells

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