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Jatropha-6(17),11 E -diene class derivatives induce apoptosis effects in OVCAR-3 and Caov-4 ovarian cancer cell lines via a mitochondrial pathway

Biochemistry and cell biology, 2017-12, Vol.95 (6), p.616-627

2017

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Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAFV600E and MEK 1 kinases via in-silico study and ADME prediction

Phytochemistry (Oxford), 2022-06, Vol.198, p.113154-113154, Article 113154

2022

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Jatrophane and rearranged jatrophane-type diterpenes: biogenesis, structure, isolation, biological activity and SARs (1984–2019)

Phytochemistry reviews, 2020-04, Vol.19 (2), p.265-336

2020

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Synthesis of the cyclopentane core of pepluanin A

Tetrahedron, 2020-03, Vol.76 (11), p.130981, Article 130981

2020

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Ingenane and jatrophane-type diterpenoids from Euphorbia kansui with multidrug resistance reversal activity

Phytochemistry (Oxford), 2021-08, Vol.188, p.112775-112775, Article 112775

2021

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Discovery of a novel highly potent and low-toxic jatrophane derivative enhancing the P-glycoprotein-mediated doxorubicin sensitivity of MCF-7/ADR cells

European journal of medicinal chemistry, 2022-12, Vol.244, p.114822-114822, Article 114822

2022

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Jatrophane diterpenoids from Euphorbia microcarpa (prokh.) krylov with multidrug resistance modulating activity

Phytochemistry (Oxford), 2022-12, Vol.204, p.113444-113444, Article 113444

2022

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Jatrophane diterpenoids with cytotoxic activity from the whole plant of Euphorbia heliosocpia L

Phytochemistry (Oxford), 2022-11, Vol.203, p.113420, Article 113420

2022

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Jatrophane diterpenoids from Euphorbia sororia as potent modulators against P-glycoprotein-based multidrug resistance

European journal of medicinal chemistry, 2018-02, Vol.146, p.157-170

2018

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Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects

Phytochemistry (Oxford), 2020-04, Vol.172, p.112257-112257, Article 112257

2020

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Bond reactivity indices approach analysis of the [2+2] cycloaddition of jatrophane skeleton diterpenoids from Euphorbia gaditana Coss to tetracyclic gaditanone

Phytochemistry (Oxford), 2020-12, Vol.180, p.112519-112519, Article 112519

2020

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Jatrophane diterpenoids as multidrug resistance modulators from Euphorbia sororia

Bioorganic chemistry, 2021-07, Vol.112, p.104989-104989, Article 104989

2021

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Jatrophane diterpenes from Euphorbia guyoniana are new potent inhibitors of atrial GIRK channels

Tetrahedron, 2016-09, Vol.72 (37), p.5724-5728

2016

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Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1088

2023

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Three new jatrophane diterpenoids from Euphorbia peplus Linn. with activity towards autophagic flux

Phytochemistry letters, 2022-08, Vol.50, p.141-146

2022

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Jatrophane polyesters from the leaves of Euphorbia peplus with anti-inflammatory activity

Phytochemistry letters, 2022-06, Vol.49, p.114-119

2022

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Bioactive Segetane, Ingenane, and Jatrophane Diterpenes from Euphorbia taurinensis

Planta medica, 2018-07, Vol.84 (9/10), p.729-735

2018

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Two new jatrophane diterpenoids from Euphorbia helioscopia with activity towards autophagic flux

Journal of asian natural products research, 2024-08, Vol.26 (8), p.900-909

2024

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Cytotoxic jatrophane diterpenoids from the aerial parts of Euphorbia helioscopia

Journal of asian natural products research, 2021-08, Vol.23 (8), p.731-737

2021

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New Jatrophane‐Type Diterpenoids from Euphorbia kansui as Potential MDR Reversal Agents

Chemistry & biodiversity, 2022-11, Vol.19 (11), p.e202200660-n/a

2022

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Macrocyclic Diterpenoids from Euphorbiaceae as A Source of Potent and Selective Inhibitors of Chikungunya Virus Replication

Molecules (Basel, Switzerland), 2019-06, Vol.24 (12), p.2336

2019

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Jatrophane diterpenes and cancer multidrug resistance – ABCB1 efflux modulation and selective cell death induction

Phytomedicine (Stuttgart), 2016-08, Vol.23 (9), p.968-978

2016

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Diterpenoids with an unusual tricyclo[10.3.0.02,9]pentadecane skeleton from Pedilanthus tithymaloides as multidrug resistance modulators

Bioorganic chemistry, 2023-09, Vol.138, p.106619-106619, Article 106619

2023

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Insights on profiling of phorbol, deoxyphorbol, ingenol and jatrophane diterpene esters by high performance liquid chromatography coupled to multiple stage mass spectrometry

Journal of Chromatography A, 2015-11, Vol.1422, p.128-139

2015

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Euphoesulatin A prevents osteoclast differentiation and bone loss via inhibiting RANKL-induced ROS production and NF-κB and MAPK signal pathways

Bioorganic chemistry, 2022-02, Vol.119, p.105511-105511, Article 105511

2022

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Jatropha-6(17),11 E -diene class derivatives induce apoptosis effects in OVCAR-3 and Caov-4 ovarian cancer cell lines via a mitochondrial pathway

Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAFV600E and MEK 1 kinases via in-silico study and ADME prediction

Jatrophane and rearranged jatrophane-type diterpenes: biogenesis, structure, isolation, biological activity and SARs (1984–2019)

Synthesis of the cyclopentane core of pepluanin A

Ingenane and jatrophane-type diterpenoids from Euphorbia kansui with multidrug resistance reversal activity

Discovery of a novel highly potent and low-toxic jatrophane derivative enhancing the P-glycoprotein-mediated doxorubicin sensitivity of MCF-7/ADR cells

Jatrophane diterpenoids from Euphorbia microcarpa (prokh.) krylov with multidrug resistance modulating activity

Jatrophane diterpenoids with cytotoxic activity from the whole plant of Euphorbia heliosocpia L

Jatrophane diterpenoids from Euphorbia sororia as potent modulators against P-glycoprotein-based multidrug resistance

Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects

Bond reactivity indices approach analysis of the [2+2] cycloaddition of jatrophane skeleton diterpenoids from Euphorbia gaditana Coss to tetracyclic gaditanone

Jatrophane diterpenoids as multidrug resistance modulators from Euphorbia sororia

Jatrophane diterpenes from Euphorbia guyoniana are new potent inhibitors of atrial GIRK channels

Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology

Three new jatrophane diterpenoids from Euphorbia peplus Linn. with activity towards autophagic flux

Jatrophane polyesters from the leaves of Euphorbia peplus with anti-inflammatory activity

Bioactive Segetane, Ingenane, and Jatrophane Diterpenes from Euphorbia taurinensis

Two new jatrophane diterpenoids from Euphorbia helioscopia with activity towards autophagic flux

Cytotoxic jatrophane diterpenoids from the aerial parts of Euphorbia helioscopia

New Jatrophane‐Type Diterpenoids from Euphorbia kansui as Potential MDR Reversal Agents

Macrocyclic Diterpenoids from Euphorbiaceae as A Source of Potent and Selective Inhibitors of Chikungunya Virus Replication

Jatrophane diterpenes and cancer multidrug resistance – ABCB1 efflux modulation and selective cell death induction

Diterpenoids with an unusual tricyclo[10.3.0.02,9]pentadecane skeleton from Pedilanthus tithymaloides as multidrug resistance modulators

Insights on profiling of phorbol, deoxyphorbol, ingenol and jatrophane diterpene esters by high performance liquid chromatography coupled to multiple stage mass spectrometry

Euphoesulatin A prevents osteoclast differentiation and bone loss via inhibiting RANKL-induced ROS production and NF-κB and MAPK signal pathways

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