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Controlling the Covalent Reactivity of a Kinase Inhibitor with Light

Angewandte Chemie (International ed.), 2021-09, Vol.60 (37), p.20178-20183

International ed. in English, 2021

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Photobiomodulation suppresses JNK3 by activation of ERK/MKP7 to attenuate AMPA receptor endocytosis in Alzheimer's disease

Aging cell, 2021-01, Vol.20 (1), p.e13289-n/a

2021

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The JNK Signaling Pathway in Inflammatory Skin Disorders and Cancer

Cells (Basel, Switzerland), 2020-04, Vol.9 (4), p.857

2020

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Arsenic Neurotoxicity in Humans

International journal of molecular sciences, 2019-07, Vol.20 (14), p.3418

Mochizuki, Hitoshi

2019

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KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS

The Journal of neuroscience, 2017-10, Vol.37 (40), p.9632-9644

2017

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Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death

Diabetologia, 2023-08, Vol.66 (8), p.1544-1556

2023

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Exosomes Secreted by Hypoxia-Pre-conditioned Adipose-Derived Mesenchymal Stem Cells Reduce Neuronal Apoptosis in Rats with Spinal Cord Injury

Journal of neurotrauma, 2022-05, Vol.39 (9-10), p.701

2022

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New insights into the structural dynamics of the kinase JNK3

Scientific reports, 2018-06, Vol.8 (1), p.9435-13, Article 9435

2018

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Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis

Nature communications, 2019-09, Vol.10 (1), p.4223-14, Article 4223

2019

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Discovery of a Potent and Selective JNK3 Inhibitor with Neuroprotective Effect Against Amyloid β-Induced Neurotoxicity in Primary Rat Neurons

International journal of molecular sciences, 2021-10, Vol.22 (20), p.11084

2021

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Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (3), p.810-815

2019

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Brain JNK and metabolic disease

Diabetologia, 2021-02, Vol.64 (2), p.265-274

2021

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Short Arrestin-3-Derived Peptides Activate JNK3 in Cells

International journal of molecular sciences, 2022-08, Vol.23 (15), p.8679

2022

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c-Jun N-Terminal Kinase Inhibitors as Potential Leads for New Therapeutics for Alzheimer's Diseases

International journal of molecular sciences, 2020-12, Vol.21 (24), p.9677

2020

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A Highly Selective In Vitro JNK3 Inhibitor, FMU200, Restores Mitochondrial Membrane Potential and Reduces Oxidative Stress and Apoptosis in SH-SY5Y Cells

International journal of molecular sciences, 2021-04, Vol.22 (7), p.3701

2021

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Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach

International journal of molecular sciences, 2018-03, Vol.19 (3), p.767

2018

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MAP kinases and the control of nuclear events

Oncogene, 2007-05, Vol.26 (22), p.3240-3253

2007

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In Silico Design of Novel Tetra-Substituted Pyridinylimidazoles Derivatives as c-Jun N-Terminal Kinase-3 Inhibitors, Using 2D/3D-QSAR Studies, Molecular Docking and ADMET Prediction

International journal of peptide research and therapeutics, 2020-09, Vol.26 (3), p.1335-1351

2020

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Novel Tryptanthrin Derivatives with Selectivity as c -Jun N-Terminal Kinase (JNK) 3 Inhibitors

Molecules (Basel, Switzerland), 2023-06, Vol.28 (12), p.4806

2023

Volltextzugriff (PDF)

Suppression of LPS-Induced Inflammation and Cell Migration by Azelastine through Inhibition of JNK/NF-κB Pathway in BV2 Microglial Cells

International journal of molecular sciences, 2021-08, Vol.22 (16), p.9061

2021

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Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice

Laboratory investigation, 2022-11, Vol.102 (11), p.1192-1202

2022

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Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats

Journal of inflammation research, 2020-01, Vol.13, p.1185-1205

2020

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Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression

PloS one, 2011-03, Vol.6 (3), p.e17596-e17596

2011

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GPCR Binding and JNK3 Activation by Arrestin-3 Have Different Structural Requirements

Cells (Basel, Switzerland), 2023-06, Vol.12 (12), p.1563

2023

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Scaffolding of Mitogen-Activated Protein Kinase Signaling by β-Arrestins

International journal of molecular sciences, 2022-01, Vol.23 (2), p.1000

2022

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Controlling the Covalent Reactivity of a Kinase Inhibitor with Light

Photobiomodulation suppresses JNK3 by activation of ERK/MKP7 to attenuate AMPA receptor endocytosis in Alzheimer's disease

The JNK Signaling Pathway in Inflammatory Skin Disorders and Cancer

Arsenic Neurotoxicity in Humans

KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS

Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death

Exosomes Secreted by Hypoxia-Pre-conditioned Adipose-Derived Mesenchymal Stem Cells Reduce Neuronal Apoptosis in Rats with Spinal Cord Injury

New insights into the structural dynamics of the kinase JNK3

Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis

Discovery of a Potent and Selective JNK3 Inhibitor with Neuroprotective Effect Against Amyloid β-Induced Neurotoxicity in Primary Rat Neurons

Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification

Brain JNK and metabolic disease

Short Arrestin-3-Derived Peptides Activate JNK3 in Cells

c-Jun N-Terminal Kinase Inhibitors as Potential Leads for New Therapeutics for Alzheimer's Diseases

A Highly Selective In Vitro JNK3 Inhibitor, FMU200, Restores Mitochondrial Membrane Potential and Reduces Oxidative Stress and Apoptosis in SH-SY5Y Cells

Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach

MAP kinases and the control of nuclear events

In Silico Design of Novel Tetra-Substituted Pyridinylimidazoles Derivatives as c-Jun N-Terminal Kinase-3 Inhibitors, Using 2D/3D-QSAR Studies, Molecular Docking and ADMET Prediction

Novel Tryptanthrin Derivatives with Selectivity as c -Jun N-Terminal Kinase (JNK) 3 Inhibitors

Suppression of LPS-Induced Inflammation and Cell Migration by Azelastine through Inhibition of JNK/NF-κB Pathway in BV2 Microglial Cells

Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice

Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats

Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression

GPCR Binding and JNK3 Activation by Arrestin-3 Have Different Structural Requirements

Scaffolding of Mitogen-Activated Protein Kinase Signaling by β-Arrestins

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