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Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer

ACS nano, 2019-01, Vol.13 (1), p.38-53

2019

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Irinotecan-Still an Important Player in Cancer Chemotherapy: A Comprehensive Overview

International journal of molecular sciences, 2020-07, Vol.21 (14), p.4919

2020

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Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial

The lancet oncology, 2021-05, Vol.22 (5), p.702-715

2021

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Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-07, Vol.1149, p.122177, Article 122177

2020

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Targeting Topoisomerase I in the Era of Precision Medicine

Clinical cancer research, 2019-11, Vol.25 (22), p.6581-6589

2019

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Blood-brain barrier disruption and delivery of irinotecan in a rat model using a clinical transcranial MRI-guided focused ultrasound system

Scientific reports, 2020-05, Vol.10 (1), p.8766-19, Article 8766

2020

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NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors

European journal of cancer (1990), 2019-02, Vol.108, p.78-87

2019

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Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience

BMC cancer, 2018-06, Vol.18 (1), p.693-693, Article 693

2018

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Prediction of irinotecan toxicity in metastatic colorectal cancer patients based on machine learning models with pharmacokinetic parameters

Journal of pharmacological sciences, 2019-05, Vol.140 (1), p.20-25

2019

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Nanoliposomal irinotecan plus fluorouracil and folinic acid as a second-line treatment option in patients with metastatic pancreatic ductal adenocarcinoma: a retrospective cohort study

BMC cancer, 2021-11, Vol.21 (1), p.1176-1176, Article 1176

2021

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Intestinal bacterial β-glucuronidase as a possible predictive biomarker of irinotecan-induced diarrhea severity

Pharmacology & therapeutics (Oxford), 2019-07, Vol.199, p.1-15

2019

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Size-Transformable Hyaluronan Stacked Self-Assembling Peptide Nanoparticles for Improved Transcellular Tumor Penetration and Photo–Chemo Combination Therapy

ACS nano, 2020-02, Vol.14 (2), p.1958-1970

2020

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Liposomal irinotecan in metastatic pancreatic adenocarcinoma in Asian patients: Subgroup analysis of the NAPOLI‐1 study

Cancer science, 2020-02, Vol.111 (2), p.513-527

2020

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Superparamagnetic chitosan nanocomplexes for colorectal tumor-targeted delivery of irinotecan

International journal of pharmaceutics, 2020-06, Vol.584, p.119394, Article 119394

2020

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Effective co-encapsulation of doxorubicin and irinotecan for synergistic therapy using liposomes prepared with triethylammonium sucrose octasulfate as drug trapping agent

International journal of pharmaceutics, 2019-02, Vol.557, p.264-272

2019

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Etoposide and cisplatin versus irinotecan and cisplatin as the first‐line therapy for patients with advanced, poorly differentiated gastroenteropancreatic neuroendocrine carcinoma: A randomized phase 2 study

Cancer, 2020-05, Vol.126 (S9), p.2086-2092

2020

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SENP1 participates in Irinotecan resistance in human colon cancer cells

Journal of cellular biochemistry, 2021-10, Vol.122 (10), p.1277-1294

2021

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Excipient-free nanodispersion of 7-ethyl-10-hydroxycamptothecin exerts potent therapeutic effects against pancreatic cancer cell lines and patient-derived xenografts

Cancer letters, 2019-11, Vol.465, p.36-44

2019

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Pharmacometabolomics Reveals Irinotecan Mechanism of Action in Cancer Patients

Journal of clinical pharmacology, 2019-01, Vol.59 (1), p.20-34

2019

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pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment

Biomedicine & pharmacotherapy, 2021-12, Vol.144, p.112317-112317, Article 112317

2021

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Nal-IRI with 5-fluorouracil (5-FU) and leucovorin or gemcitabine plus cisplatin in advanced biliary tract cancer - the NIFE trial (AIO-YMO HEP-0315) an open label, non-comparative, randomized, multicenter phase II study

BMC cancer, 2019-10, Vol.19 (1), p.990-990, Article 990

2019

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Irinotecan: 25 years of cancer treatment

Pharmacological research, 2019-10, Vol.148, p.104398-104398, Article 104398

Bailly, Christian

2019

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Author Correction: The Impact of Liposomal Irinotecan on the Treatment of Advanced Pancreatic Adenocarcinoma: Real-World Experience in a Taiwanese Cohort

Scientific reports, 2020-11, Vol.10 (1), p.20199-20199, Article 20199

2020

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Pharmacokinetic and Pharmacogenetic Markers of Irinotecan Toxicity

Current medicinal chemistry, 2019-01, Vol.26 (12), p.2085

2019

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