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CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection

The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4557-4572

2018

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Central Role for Interleukin-2 in Type 1 Diabetes

Diabetes (New York, N.Y.), 2012-01, Vol.61 (1), p.14-22

2012

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Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation tolerance

The Journal of clinical investigation, 2021-04, Vol.131 (8), p.1-13

2021

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

Nature Immunology, 2005-11, Vol.6 (11), p.1142-1151

2005

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STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (46), p.12111-12119

2017

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FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

Cell, 2006-07, Vol.126 (2), p.375-387

2006

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Zinc in human health: effect of zinc on immune cells

Molecular medicine (Cambridge, Mass.), 2008-05, Vol.14 (5-6), p.353-357

Prasad, Ananda S

2008

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Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling

Nature chemical biology, 2016-05, Vol.12 (5), p.373-379

2016

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Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

The Journal of immunology (1950), 2002-11, Vol.169 (9), p.4850-4860

2002

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Development and function of agonist-induced CD25 + Foxp3 + regulatory T cells in the absence of interleukin 2 signaling

Nature immunology, 2005-11, Vol.6 (11), p.1152-1159

2005

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Whole exome sequencing identified a novel splice donor site variant in interleukin 2 receptor alpha chain

Immunogenetics (New York), 2023-04, Vol.75 (2), p.71-79

2023

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Both integrated and differential regulation of components of the IL-2/IL-2 receptor system

Cytokine & growth factor reviews, 2006-10, Vol.17 (5), p.349-366

2006

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Dietary Selenium Modulates Activation and Differentiation of CD4⁺ T Cells in Mice through a Mechanism Involving Cellular Free Thiols

The Journal of nutrition, 2010-06, Vol.140 (6), p.1155-1161

2010

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CD4 + and CD8 + regulatory T cell characterization in the rat using a unique transgenic Foxp3-EGFP model

BMC biology, 2023-01, Vol.21 (1), p.8-8, Article 8

2023

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Differential effects of IL-12 on Tregs and non-Treg T cells: roles of IFN-γ, IL-2 and IL-2R

PloS one, 2012-09, Vol.7 (9), p.e46241

2012

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A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease

Journal of autoimmunity, 2018-12, Vol.95, p.1-14

2018

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Regulation of autoimmune disease by the E3 ubiquitin ligase Itch

Cellular immunology, 2019-06, Vol.340, p.103916-103916, Article 103916

2019

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Signaling function of PRC2 is essential for TCR-driven T cell responses

The Journal of experimental medicine, 2018-04, Vol.215 (4), p.1101-1113

2018

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Dendritic cell derived IL‐2 inhibits survival of terminally mature cells via an autocrine signaling pathway

European journal of immunology, 2015-05, Vol.45 (5), p.1494-1499

2015

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Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function

The Journal of immunology (1950), 2012-05, Vol.188 (9), p.4644-4653

2012

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Cytokine-Dependent Blimp-1 Expression in Activated T Cells Inhibits IL-2 Production

Journal of Immunology, 2007-01, Vol.178 (1), p.242-252

2007

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Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’

Nature (London), 2012-04, Vol.484 (7395), p.529-533

2012

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An Immune Risk Phenotype, Cognitive Impairment, and Survival in Very Late Life: Impact of Allostatic Load in Swedish Octogenarian and Nonagenarian Humans

The journals of gerontology. Series A, Biological sciences and medical sciences, 2005-05, Vol.60 (5), p.556-565

2005

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Activation of human naïve Th cells increases surface expression of GD3 and induces neoexpression of GD2 that colocalize with TCR clusters

Glycobiology (Oxford), 2015-12, Vol.25 (12), p.1454-1464

2015

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PIM1 Kinase Phosphorylates the Human Transcription Factor FOXP3 at Serine 422 to Negatively Regulate Its Activity under Inflammation

The Journal of biological chemistry, 2014-09, Vol.289 (39), p.26872-26881

2014

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CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection

Central Role for Interleukin-2 in Type 1 Diabetes

Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation tolerance

A function for interleukin 2 in Foxp3-expressing regulatory T cells

STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus

FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

Zinc in human health: effect of zinc on immune cells

Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

Development and function of agonist-induced CD25 + Foxp3 + regulatory T cells in the absence of interleukin 2 signaling

Whole exome sequencing identified a novel splice donor site variant in interleukin 2 receptor alpha chain

Both integrated and differential regulation of components of the IL-2/IL-2 receptor system

Dietary Selenium Modulates Activation and Differentiation of CD4⁺ T Cells in Mice through a Mechanism Involving Cellular Free Thiols

CD4 + and CD8 + regulatory T cell characterization in the rat using a unique transgenic Foxp3-EGFP model

Differential effects of IL-12 on Tregs and non-Treg T cells: roles of IFN-γ, IL-2 and IL-2R

A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease

Regulation of autoimmune disease by the E3 ubiquitin ligase Itch

Signaling function of PRC2 is essential for TCR-driven T cell responses

Dendritic cell derived IL‐2 inhibits survival of terminally mature cells via an autocrine signaling pathway

Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function

Cytokine-Dependent Blimp-1 Expression in Activated T Cells Inhibits IL-2 Production

Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’

An Immune Risk Phenotype, Cognitive Impairment, and Survival in Very Late Life: Impact of Allostatic Load in Swedish Octogenarian and Nonagenarian Humans

Activation of human naïve Th cells increases surface expression of GD3 and induces neoexpression of GD2 that colocalize with TCR clusters

PIM1 Kinase Phosphorylates the Human Transcription Factor FOXP3 at Serine 422 to Negatively Regulate Its Activity under Inflammation

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