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Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10

Science (American Association for the Advancement of Science), 2021-03, Vol.371 (6535)

2021

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The structural network of Interleukin-10 and its implications in inflammation and cancer

BMC genomics, 2014-05, Vol.15 Suppl 4 (S4), p.S2-S2, Article S2

2014

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The molecular basis of IL-10 function: from receptor structure to the onset of signaling

Current topics in microbiology and immunology, 2014, Vol.380, p.191

Walter, Mark R

2014

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Structural analysis of cytokines comprising the IL-10 family

Cytokine & growth factor reviews, 2010-10, Vol.21 (5), p.325-330

Zdanov, Alexander

2010

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Regulation and functions of the IL-10 family of cytokines in inflammation and disease

Annual review of immunology, 2011-04, Vol.29 (1), p.71-109

2011

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Targeting IL-10 Family Cytokines for the Treatment of Human Diseases

Cold Spring Harbor perspectives in biology, 2019-02, Vol.11 (2), p.a028548

2019

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Conformational Changes Mediate Interleukin-10 Receptor 2 (IL-10R2) Binding to IL-10 and Assembly of the Signaling Complex

The Journal of biological chemistry, 2006-11, Vol.281 (46), p.35088-35096

2006

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PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients

Cancer cell, 2018-11, Vol.34 (5), p.775-791.e3

2018

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Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain

Structure (London), 2008-09, Vol.16 (9), p.1333-1344

2008

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Modulation of human immune responses by bovine interleukin-10

PloS one, 2011-03, Vol.6 (3), p.e18188

2011

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The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function

Frontiers in immunology, 2020-08, Vol.11, p.1794-1794

2020

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Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

The New England journal of medicine, 2009-11, Vol.361 (21), p.2033-2045

2009

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Engineering Microsphere-Loaded Non-mulberry Silk-Based 3D Bioprinted Vascularized Cardiac Patches with Oxygen-Releasing and Immunomodulatory Potential

ACS applied materials & interfaces, 2021-11, Vol.13 (43), p.50744-50759

2021

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Injectable Supramolecular Hydrogel/Microgel Composites for Therapeutic Delivery

Macromolecular bioscience, 2019-01, Vol.19 (1), p.e1800248-n/a

2019

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A fully integrated electrochemical biosensor platform fabrication process for cytokines detection

Biosensors & bioelectronics, 2017-07, Vol.93, p.170-175

2017

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Coacervate-mediated exogenous growth factor delivery for scarless skin regeneration

Acta biomaterialia, 2019-05, Vol.90, p.179-191

2019

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Rational Structure-Based Rescaffolding Approach to De Novo Design of Interleukin 10 (IL-10) Receptor-1 Mimetics

PloS one, 2016-04, Vol.11 (4), p.e0154046-e0154046

2016

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Identification of the Glycosaminoglycan Binding Site of Interleukin-10 by NMR Spectroscopy

The Journal of biological chemistry, 2016-02, Vol.291 (6), p.3100-3113

2016

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Investigation of the structure of regulatory proteins interacting with glycosaminoglycans by combining NMR spectroscopy and molecular modeling - the beginning of a wonderful friendship

Biological chemistry, 2021-10, Vol.402 (11), p.1337-1355

2021

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Ion Mobility-Mass Spectrometry and Collision-Induced Unfolding Rapidly Characterize the Structural Polydispersity and Stability of an Fc-Fusion Protein

Analytical chemistry (Washington), 2024-06, Vol.96 (24), p.10003-10012

2024

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Molecular characterization and expression of interleukin-10 and interleukin-22 in golden pompano (Trachinotus ovatus) in response to Streptococcus agalactiae stimulus

Fish & shellfish immunology, 2017-06, Vol.65, p.244-255

2017

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Interleukin-10 and related cytokines and receptors

Annual review of immunology, 2004-01, Vol.22, p.929-979

2004

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Interleukin-10 levels and the risk of thromboembolism according to COMPASS-Cancer associated thrombosis score in breast cancer patients prior to undergoing doxorubicin-based chemotherapy

Blood coagulation & fibrinolysis, 2023-01, Vol.34 (1), p.70

2023

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IL10, A Tale of an Evolutionarily Conserved Cytokine across Vertebrates

Critical reviews in immunology, 2016, Vol.36 (2), p.99-129

2016

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Interleukin-10 conjugated electrospun polycaprolactone (PCL) nanofibre scaffolds for promoting alternatively activated (M2) macrophages around the peripheral nerve in vivo

Journal of immunological methods, 2015-05, Vol.420, p.38-49

2015

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Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10

The structural network of Interleukin-10 and its implications in inflammation and cancer

The molecular basis of IL-10 function: from receptor structure to the onset of signaling

Structural analysis of cytokines comprising the IL-10 family

Regulation and functions of the IL-10 family of cytokines in inflammation and disease

Targeting IL-10 Family Cytokines for the Treatment of Human Diseases

Conformational Changes Mediate Interleukin-10 Receptor 2 (IL-10R2) Binding to IL-10 and Assembly of the Signaling Complex

PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients

Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain

Modulation of human immune responses by bovine interleukin-10

The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

Engineering Microsphere-Loaded Non-mulberry Silk-Based 3D Bioprinted Vascularized Cardiac Patches with Oxygen-Releasing and Immunomodulatory Potential

Injectable Supramolecular Hydrogel/Microgel Composites for Therapeutic Delivery

A fully integrated electrochemical biosensor platform fabrication process for cytokines detection

Coacervate-mediated exogenous growth factor delivery for scarless skin regeneration

Rational Structure-Based Rescaffolding Approach to De Novo Design of Interleukin 10 (IL-10) Receptor-1 Mimetics

Identification of the Glycosaminoglycan Binding Site of Interleukin-10 by NMR Spectroscopy

Investigation of the structure of regulatory proteins interacting with glycosaminoglycans by combining NMR spectroscopy and molecular modeling - the beginning of a wonderful friendship

Ion Mobility-Mass Spectrometry and Collision-Induced Unfolding Rapidly Characterize the Structural Polydispersity and Stability of an Fc-Fusion Protein

Molecular characterization and expression of interleukin-10 and interleukin-22 in golden pompano (Trachinotus ovatus) in response to Streptococcus agalactiae stimulus

Interleukin-10 and related cytokines and receptors

Interleukin-10 levels and the risk of thromboembolism according to COMPASS-Cancer associated thrombosis score in breast cancer patients prior to undergoing doxorubicin-based chemotherapy

IL10, A Tale of an Evolutionarily Conserved Cytokine across Vertebrates

Interleukin-10 conjugated electrospun polycaprolactone (PCL) nanofibre scaffolds for promoting alternatively activated (M2) macrophages around the peripheral nerve in vivo

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