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A cryptic non–GPI‐anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β‐cells by interaction with SNARE proteins

The FASEB journal, 2019-11, Vol.33 (11), p.12425-12434

2019

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Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice

Protein engineering, design and selection, 2019-12, Vol.32 (2), p.95-102

2019

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Angiotensin II Type 1 Receptor Blockade Improves β-Cell Function and Glucose Tolerance in a Mouse Model of Type 2 Diabetes

Diabetes (New York, N.Y.), 2006-02, Vol.55 (2), p.367-374

2006

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Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish

Developmental biology, 2012-05, Vol.365 (1), p.290-302

2012

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Glutaredoxin-1 Mediates NADPH-Dependent Stimulation of Calcium-Dependent Insulin Secretion

Molecular endocrinology (Baltimore, Md.), 2009-06, Vol.23 (6), p.893-900

2009

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Deciphering Structure–Activity Relationships in a Series of 2,2‐Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants

ChemMedChem, 2017-11, Vol.12 (21), p.1810-1817

2017

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Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

The EMBO journal, 2015-07, Vol.34 (13), p.1759-1772

2015

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Charting cellular identity during human in vitro β-cell differentiation

Nature (London), 2019-05, Vol.569 (7756), p.368-373

2019

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Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets

Diabetologia, 2006-06, Vol.49 (6), p.1237-1246

2006

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Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

Nature cell biology, 2019-02, Vol.21 (2), p.263

2019

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Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells

Nature biotechnology, 2020-04, Vol.38 (4), p.460-470

2020

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Mechanisms controlling pancreatic islet cell function in insulin secretion

Nature reviews. Molecular cell biology, 2021-02, Vol.22 (2), p.142

2021

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A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

The Journal of clinical investigation, 2011-09, Vol.121 (9), p.3589-3597

2011

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Diabetes Mellitus and the β Cell: The Last Ten Years

Cell, 2012-03, Vol.148 (6), p.1160-1171

2012

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Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation

Cell stem cell, 2016-03, Vol.18 (3), p.410-421

2016

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Signals in the pancreatic islet microenvironment influence β‐cell proliferation

Diabetes, obesity & metabolism, 2017-09, Vol.19 (S1), p.124-136

2017

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Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

Cell metabolism, 2019-02, Vol.29 (2), p.348-361.e6

2019

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Exosomes as new players in metabolic organ cross‐talk

Diabetes, obesity & metabolism, 2017-09, Vol.19 (S1), p.137-146

2017

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Impact of islet architecture on β-cell heterogeneity, plasticity and function

Nature reviews. Endocrinology, 2016-12, Vol.12 (12), p.695

2016

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Single-Cell RNA-Seq of the Pancreatic Islets––a Promise Not yet Fulfilled?

Cell metabolism, 2019-03, Vol.29 (3), p.539-544

2019

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Human pancreatic beta-like cells converted from fibroblasts

Nature communications, 2016-01, Vol.7 (1), p.10080-10080, Article 10080

2016

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Generation of Functional Human Pancreatic β Cells In Vitro

Cell, 2014-10, Vol.159 (2), p.428-439

2014

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δ‐cells and β‐cells are electrically coupled and regulate α‐cell activity via somatostatin

The Journal of physiology, 2018-01, Vol.596 (2), p.197-215

2018

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How to make a functional β-cell

Development (Cambridge), 2013-06, Vol.140 (12), p.2472-2483

2013

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A cryptic non–GPI‐anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β‐cells by interaction with SNARE proteins

Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice

Angiotensin II Type 1 Receptor Blockade Improves β-Cell Function and Glucose Tolerance in a Mouse Model of Type 2 Diabetes

Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish

Glutaredoxin-1 Mediates NADPH-Dependent Stimulation of Calcium-Dependent Insulin Secretion

Deciphering Structure–Activity Relationships in a Series of 2,2‐Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

Charting cellular identity during human in vitro β-cell differentiation

Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets

Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells

Mechanisms controlling pancreatic islet cell function in insulin secretion

Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

Diabetes Mellitus and the β Cell: The Last Ten Years

Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation

Signals in the pancreatic islet microenvironment influence β‐cell proliferation

Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

Exosomes as new players in metabolic organ cross‐talk

Impact of islet architecture on β-cell heterogeneity, plasticity and function

Single-Cell RNA-Seq of the Pancreatic Islets––a Promise Not yet Fulfilled?

Human pancreatic beta-like cells converted from fibroblasts

Generation of Functional Human Pancreatic β Cells In Vitro

δ‐cells and β‐cells are electrically coupled and regulate α‐cell activity via somatostatin

How to make a functional β-cell

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