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Redox states in the endoplasmic reticulum directly regulate the activity of calcium channel, inositol 1,4,5-trisphosphate receptors

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (22), p.e2216857120-e2216857120

2023

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Differential Regulation of Multiple Steps in Inositol 1,4,5-Trisphosphate Signaling by Protein Kinase C Shapes Hormone-stimulated Ca2+ Oscillations

The Journal of biological chemistry, 2015-07, Vol.290 (30), p.18519-18533

2015

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ITPK1 mediates the lipid-independent synthesis of inositol phosphates controlled by metabolism

Proceedings of the National Academy of Sciences - PNAS, 2019-12, Vol.116 (49), p.24551-24561

2019

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Altered Ovarian Inositol Ratios May Account for Pathological Steroidogenesis in PCOS

International journal of molecular sciences, 2020-10, Vol.21 (19), p.7157

2020

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Pharmacodynamics and pharmacokinetics of inositol(s) in health and disease

Expert opinion on drug metabolism & toxicology, 2016-10, Vol.12 (10), p.1181-1196

2016

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Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity

Nature communications, 2024-02, Vol.15 (1), p.1502-1502, Article 1502

2024

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Inositol as putative integrative treatment for PCOS

Reproductive biomedicine online, 2016-12, Vol.33 (6), p.770-780

Genazzani, Alessandro D

2016

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Enhancing glucaric acid production from myo -inositol in Escherichia coli by eliminating cell-to-cell variation

Applied and environmental microbiology, 2024-06, Vol.90 (6), p.e0014924

2024

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Physiological, Biochemical, and Structural Bioinformatic Analysis of the Multiple Inositol Dehydrogenases from Corynebacterium glutamicum

Microbiology spectrum, 2022-10, Vol.10 (5), p.e0195022-e0195022

2022

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Disorder-to-order active site capping regulates the rate-limiting step of the inositol pathway

Proceedings of the National Academy of Sciences - PNAS, 2024-08, Vol.121 (34), p.e2400912121

2024

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The cellular language of myo-inositol signaling

The New phytologist, 2011-12, Vol.192 (4), p.823-839

Gillaspy, Glenda E.

2011

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Potential of engineering the myo-inositol oxidation pathway to increase stress resilience in plants

Molecular biology reports, 2022-08, Vol.49 (8), p.8025-8035

2022

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Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain

Cell, 2010-12, Vol.143 (6), p.897-910

2010

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Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

Nature communications, 2017-06, Vol.8 (1), p.15732-15732, Article 15732

2017

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The Function of Inositol Phosphatases in Plant Tolerance to Abiotic Stress

International journal of molecular sciences, 2019-08, Vol.20 (16), p.3999

2019

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Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli

Metabolic engineering, 2010-05, Vol.12 (3), p.298-305

2010

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Structural and functional conservation of the activating Ca 2+ binding site in inositol 1,4.5-trisphosphate and ryanodine receptors

Cell calcium (Edinburgh), 2022-12, Vol.108, p.102671

2022

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Inositol in Disease and Development: Roles of Catabolism via myo -Inositol Oxygenase in Drosophila melanogaster

International journal of molecular sciences, 2023-02, Vol.24 (4), p.4185

2023

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Genome-wide identification of the myo-inositol oxygenase gene family in alfalfa (Medicago sativa L.) and expression analysis under abiotic stress

Plant physiology and biochemistry, 2023-07, Vol.200, p.107787-107787, Article 107787

2023

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Sequence-based bioprospecting of myo-inositol oxygenase (Miox) reveals new homologues that increase glucaric acid production in Saccharomyces cerevisiae

Enzyme and microbial technology, 2020-10, Vol.140, p.109623-109623, Article 109623

2020

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HERPUD1 governs tumor cell mitochondrial function via inositol 1,4,5-trisphosphate receptor-mediated calcium signaling

Free radical biology & medicine, 2024-02, Vol.211, p.24-34

2024

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Down-regulation of the myo-inositol oxygenase gene family has no effect on cell wall composition in Arabidopsis

Planta, 2011-07, Vol.234 (1), p.157-169

2011

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Renal depletion of myo-inositol is associated with its increased degradation in animal models of metabolic disease

American journal of physiology. Renal physiology, 2015-11, Vol.309 (9), p.F755-F763

2015

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Improving d-glucaric acid production from myo-inositol in E. coli by increasing MIOX stability and myo-inositol transport

Metabolic engineering, 2014-03, Vol.22, p.22-31

2014

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Production of glucaric acid from myo-inositol in engineered Pichia pastoris

Enzyme and microbial technology, 2016-09, Vol.91, p.8-16

2016

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Redox states in the endoplasmic reticulum directly regulate the activity of calcium channel, inositol 1,4,5-trisphosphate receptors

Differential Regulation of Multiple Steps in Inositol 1,4,5-Trisphosphate Signaling by Protein Kinase C Shapes Hormone-stimulated Ca2+ Oscillations

ITPK1 mediates the lipid-independent synthesis of inositol phosphates controlled by metabolism

Altered Ovarian Inositol Ratios May Account for Pathological Steroidogenesis in PCOS

Pharmacodynamics and pharmacokinetics of inositol(s) in health and disease

Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity

Inositol as putative integrative treatment for PCOS

Enhancing glucaric acid production from myo -inositol in Escherichia coli by eliminating cell-to-cell variation

Physiological, Biochemical, and Structural Bioinformatic Analysis of the Multiple Inositol Dehydrogenases from Corynebacterium glutamicum

Disorder-to-order active site capping regulates the rate-limiting step of the inositol pathway

The cellular language of myo-inositol signaling

Potential of engineering the myo-inositol oxidation pathway to increase stress resilience in plants

Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain

Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

The Function of Inositol Phosphatases in Plant Tolerance to Abiotic Stress

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli

Structural and functional conservation of the activating Ca 2+ binding site in inositol 1,4.5-trisphosphate and ryanodine receptors

Inositol in Disease and Development: Roles of Catabolism via myo -Inositol Oxygenase in Drosophila melanogaster

Genome-wide identification of the myo-inositol oxygenase gene family in alfalfa (Medicago sativa L.) and expression analysis under abiotic stress

Sequence-based bioprospecting of myo-inositol oxygenase (Miox) reveals new homologues that increase glucaric acid production in Saccharomyces cerevisiae

HERPUD1 governs tumor cell mitochondrial function via inositol 1,4,5-trisphosphate receptor-mediated calcium signaling

Down-regulation of the myo-inositol oxygenase gene family has no effect on cell wall composition in Arabidopsis

Renal depletion of myo-inositol is associated with its increased degradation in animal models of metabolic disease

Improving d-glucaric acid production from myo-inositol in E. coli by increasing MIOX stability and myo-inositol transport

Production of glucaric acid from myo-inositol in engineered Pichia pastoris

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