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Nontherapeutic equivalence of a generic product of imipenem-cilastatin is caused more by chemical instability of the active pharmaceutical ingredient (imipenem) than by its substandard amount of cilastatin

PloS one, 2019-02, Vol.14 (2), p.e0211096-e0211096

2019

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Carbapenems: Past, Present, and Future

Antimicrobial Agents and Chemotherapy, 2011-11, Vol.55 (11), p.4943-4960

2011

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Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations

Drugs (New York, N.Y.), 2018, Vol.78 (1), p.65-98

2018

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Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection

Nature communications, 2019-09, Vol.10 (1), p.4336-12, Article 4336

2019

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New Perspectives on Antimicrobial Agents: Imipenem-Relebactam

Antimicrobial agents and chemotherapy, 2022-07, Vol.66 (7), p.e0025622

2022

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Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms

Journal of medicinal chemistry, 2017-10, Vol.60 (20), p.8268-8297

2017

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Imipenem/Cilastatin/Relebactam: A Review in Gram-Negative Bacterial Infections

Drugs (New York, N.Y.), 2021-02, Vol.81 (3), p.377-388

Heo, Young-A.

2021

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Evolution of Imipenem-Relebactam Resistance Following Treatment of Multidrug-Resistant Pseudomonas aeruginosa Pneumonia

Clinical infectious diseases, 2022-09, Vol.75 (4), p.710-714

2022

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Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa

Journal of antimicrobial chemotherapy, 2022-09, Vol.77 (10), p.2809-2815

2022

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Evaluation of the inoculum effect of new antibiotics against carbapenem-resistant enterobacterales

Clinical microbiology and infection, 2022-11, Vol.28 (11), p.1503.e1-1503.e3

2022

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In Vitro Activity of Ceftolozane-Tazobactam, Imipenem-Relebactam, Ceftazidime-Avibactam, and Comparators against Pseudomonas aeruginosa Isolates Collected in United States Hospitals According to Results from the SMART Surveillance Program, 2018 to 2020

Antimicrobial agents and chemotherapy, 2022-05, Vol.66 (5), p.e0018922

2022

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In Vitro Activity of Imipenem-Relebactam against Gram-Negative ESKAPE Pathogens Isolated by Clinical Laboratories in the United States in 2015 (Results from the SMART Global Surveillance Program)

Antimicrobial agents and chemotherapy, 2017-06, Vol.61 (6)

2017

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Identifying Spectra of Activity and Therapeutic Niches for Ceftazidime-Avibactam and Imipenem-Relebactam against Carbapenem-Resistant Enterobacteriaceae

Antimicrobial agents and chemotherapy, 2017-09, Vol.61 (9)

2017

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Pharmacokinetics/Pharmacodynamics of Colistin and Imipenem on Mucoid and Nonmucoid Pseudomonas aeruginosa Biofilms

Antimicrobial Agents and Chemotherapy, 2011-09, Vol.55 (9), p.4469-4474

2011

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In vitro studies evaluating the activity of imipenem in combination with relebactam against Pseudomonas aeruginosa

BMC microbiology, 2019-07, Vol.19 (1), p.150-14, Article 150

2019

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Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City

Antimicrobial agents and chemotherapy, 2015-08, Vol.59 (8), p.5029-5031

2015

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Comparative review of the carbapenems

Drugs (New York, N.Y.), 2007-01, Vol.67 (7), p.1027-1052

2007

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Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.780-785

2014

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In vitro activities of cefiderocol, ceftolozane/tazobactam, ceftazidime/avibactam and other comparative drugs against imipenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii, and Stenotrophomonas maltophilia, all associated with bloodstream infections in Taiwan

Journal of antimicrobial chemotherapy, 2019-02, Vol.74 (2), p.380-386

2019

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Molecular Basis of Class A β-Lactamase Inhibition by Relebactam

Antimicrobial agents and chemotherapy, 2019-10, Vol.63 (10)

2019

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In Vitro and Intracellular Activity of Imipenem Combined with Tedizolid, Rifabutin, and Avibactam against Mycobacterium abscessus

Antimicrobial agents and chemotherapy, 2019-04, Vol.63 (4)

2019

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Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and Isogenic β-Lactam-Resistant Mutants

Antimicrobial agents and chemotherapy, 2020-01, Vol.64 (2)

2020

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In Vitro Activity of Imipenem against Carbapenemase-Positive Enterobacteriaceae Isolates Collected by the SMART Global Surveillance Program from 2008 to 2014

Journal of clinical microbiology, 2017-06, Vol.55 (6), p.1638-1649

2017

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Insights into the l,d-Transpeptidases and d,d-Carboxypeptidase of Mycobacterium abscessus: Ceftaroline, Imipenem, and Novel Diazabicyclooctane Inhibitors

Antimicrobial agents and chemotherapy, 2020-07, Vol.64 (8)

2020

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Imipenem-Relebactam Susceptibility in Enterobacterales Isolates Recovered from ICU Patients from Spain and Portugal (SUPERIOR and STEP Studies)

Nontherapeutic equivalence of a generic product of imipenem-cilastatin is caused more by chemical instability of the active pharmaceutical ingredient (imipenem) than by its substandard amount of cilastatin

Carbapenems: Past, Present, and Future

Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations

Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection

New Perspectives on Antimicrobial Agents: Imipenem-Relebactam

Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms

Imipenem/Cilastatin/Relebactam: A Review in Gram-Negative Bacterial Infections

Evolution of Imipenem-Relebactam Resistance Following Treatment of Multidrug-Resistant Pseudomonas aeruginosa Pneumonia

Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa

Evaluation of the inoculum effect of new antibiotics against carbapenem-resistant enterobacterales

In Vitro Activity of Ceftolozane-Tazobactam, Imipenem-Relebactam, Ceftazidime-Avibactam, and Comparators against Pseudomonas aeruginosa Isolates Collected in United States Hospitals According to Results from the SMART Surveillance Program, 2018 to 2020

In Vitro Activity of Imipenem-Relebactam against Gram-Negative ESKAPE Pathogens Isolated by Clinical Laboratories in the United States in 2015 (Results from the SMART Global Surveillance Program)

Identifying Spectra of Activity and Therapeutic Niches for Ceftazidime-Avibactam and Imipenem-Relebactam against Carbapenem-Resistant Enterobacteriaceae

Pharmacokinetics/Pharmacodynamics of Colistin and Imipenem on Mucoid and Nonmucoid Pseudomonas aeruginosa Biofilms

In vitro studies evaluating the activity of imipenem in combination with relebactam against Pseudomonas aeruginosa

Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City

Comparative review of the carbapenems

Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin

In vitro activities of cefiderocol, ceftolozane/tazobactam, ceftazidime/avibactam and other comparative drugs against imipenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii, and Stenotrophomonas maltophilia, all associated with bloodstream infections in Taiwan

Molecular Basis of Class A β-Lactamase Inhibition by Relebactam

In Vitro and Intracellular Activity of Imipenem Combined with Tedizolid, Rifabutin, and Avibactam against Mycobacterium abscessus

Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and Isogenic β-Lactam-Resistant Mutants

In Vitro Activity of Imipenem against Carbapenemase-Positive Enterobacteriaceae Isolates Collected by the SMART Global Surveillance Program from 2008 to 2014

Insights into the l,d-Transpeptidases and d,d-Carboxypeptidase of Mycobacterium abscessus: Ceftaroline, Imipenem, and Novel Diazabicyclooctane Inhibitors

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