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RidA Proteins Protect against Metabolic Damage by Reactive Intermediates

Microbiology and molecular biology reviews, 2020-08, Vol.84 (3)

2020

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Artificial Metalloenzymes: Reaction Scope and Optimization Strategies

Chemical reviews, 2018-01, Vol.118 (1), p.142-231

2018

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Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women

Clinical pharmacokinetics, 2020-01, Vol.59 (1), p.97-110

2020

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Exploiting and engineering hemoproteins for abiological carbene and nitrene transfer reactions

Current opinion in biotechnology, 2017-10, Vol.47, p.102-111

2017

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Imine reductases (IREDs)

Current opinion in chemical biology, 2017-04, Vol.37, p.19-25

2017

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A triple cysteine motif as major determinant of the modulation of neuronal K V 7 channels by the paracetamol metabolite N-acetyl-p-benzo quinone imine

British journal of pharmacology, 2024-08, Vol.181 (16), p.2851-2868

2024

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Asymmetric Synthesis of N‐Substituted α‐Amino Esters from α‐Ketoesters via Imine Reductase‐Catalyzed Reductive Amination

Angewandte Chemie International Edition, 2021-04, Vol.60 (16), p.8717-8721

International ed. in English, 2021

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Bromine is an essential trace element for assembly of collagen IV scaffolds in tissue development and architecture

Cell, 2014-06, Vol.157 (6), p.1380-1392

2014

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Chemicals and Drugs Forming Reactive Quinone and Quinone Imine Metabolites

Chemical research in toxicology, 2019-01, Vol.32 (1), p.1-34

2019

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Recent developments in the application of P450 based biocatalysts

Current opinion in chemical biology, 2018-04, Vol.43, p.1-7

2018

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Asymmetric Synthesis of Sterically Hindered 1‑Substituted Tetrahydro-β-carbolines Enabled by Imine Reductase: Enzyme Discovery, Protein Engineering, and Reaction Development

Organic letters, 2023-03, Vol.25 (8), p.1285-1289

2023

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Enzymatic Synthesis of Unprotected α,β-Diamino Acids via Direct Asymmetric Mannich Reactions

Journal of the American Chemical Society, 2024-07, Vol.146 (29), p.20263-20269

2024

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Genetic and Molecular Basis for Sunscreen Biosynthesis in Cyanobacteria

Science (American Association for the Advancement of Science), 2010-09, Vol.329 (5999), p.1653-1656

2010

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Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (13), p.6076-6081

2010

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Occurrence of marine algal toxins in oyster and phytoplankton samples in Daya Bay, South China Sea

Chemosphere (Oxford), 2017-09, Vol.183, p.80-88

2017

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Atroposelective Synthesis of Axial Biaryls by Dynamic Kinetic Resolution Using Engineered Imine Reductases

Angewandte Chemie International Edition, 2024-10, Vol.63 (41), p.e202410112-n/a

International ed. in English, 2024

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Biocatalytic Asymmetric Cyclopropanations via Enzyme‐Bound Iminium Ion Intermediates

Angewandte Chemie International Edition, 2021-11, Vol.60 (45), p.24059-24063

International ed. in English, 2021

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Biomimetic Hydrogenation Catalyzed by a Manganese Model of [Fe]‐Hydrogenase

Angewandte Chemie International Edition, 2020-03, Vol.59 (12), p.4942-4946

International ed. in English, 2020

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Kinetic and structural analysis of redox-reversible artificial imine reductases

Journal of inorganic biochemistry, 2024-11, Vol.260, p.112691, Article 112691

2024

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Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease

Liver international, 2014-08, Vol.34 (7), p.e171-e179

2014

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Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination

Nature chemistry, 2021-02, Vol.13 (2), p.140-148

2021

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Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases

Chembiochem : a European journal of chemical biology, 2014-10, Vol.15 (15), p.2201-2204

2014

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Structure of the iminium reaction intermediate in an engineered aldolase explains the carboligation activity toward arylated ketones and aldehydes

Structure (London), 2024-09, Vol.32 (9), p.1322-1326.e4

2024

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Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils

The Journal of immunology (1950), 2008-02, Vol.180 (3), p.1895-1902

2008

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Snapshots of PLP‐substrate and PLP‐product external aldimines as intermediates in two types of cysteine desulfurase enzymes

The FEBS journal, 2020-03, Vol.287 (6), p.1138-1154

2020

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RidA Proteins Protect against Metabolic Damage by Reactive Intermediates

Artificial Metalloenzymes: Reaction Scope and Optimization Strategies

Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women

Exploiting and engineering hemoproteins for abiological carbene and nitrene transfer reactions

Imine reductases (IREDs)

A triple cysteine motif as major determinant of the modulation of neuronal K V 7 channels by the paracetamol metabolite N-acetyl-p-benzo quinone imine

Asymmetric Synthesis of N‐Substituted α‐Amino Esters from α‐Ketoesters via Imine Reductase‐Catalyzed Reductive Amination

Bromine is an essential trace element for assembly of collagen IV scaffolds in tissue development and architecture

Chemicals and Drugs Forming Reactive Quinone and Quinone Imine Metabolites

Recent developments in the application of P450 based biocatalysts

Asymmetric Synthesis of Sterically Hindered 1‑Substituted Tetrahydro-β-carbolines Enabled by Imine Reductase: Enzyme Discovery, Protein Engineering, and Reaction Development

Enzymatic Synthesis of Unprotected α,β-Diamino Acids via Direct Asymmetric Mannich Reactions

Genetic and Molecular Basis for Sunscreen Biosynthesis in Cyanobacteria

Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism

Occurrence of marine algal toxins in oyster and phytoplankton samples in Daya Bay, South China Sea

Atroposelective Synthesis of Axial Biaryls by Dynamic Kinetic Resolution Using Engineered Imine Reductases

Biocatalytic Asymmetric Cyclopropanations via Enzyme‐Bound Iminium Ion Intermediates

Biomimetic Hydrogenation Catalyzed by a Manganese Model of [Fe]‐Hydrogenase

Kinetic and structural analysis of redox-reversible artificial imine reductases

Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease

Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination

Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases

Structure of the iminium reaction intermediate in an engineered aldolase explains the carboligation activity toward arylated ketones and aldehydes

Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils

Snapshots of PLP‐substrate and PLP‐product external aldimines as intermediates in two types of cysteine desulfurase enzymes

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