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Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement

Nature communications, 2018-04, Vol.9 (1), p.1421-15, Article 1421

2018

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General mechanism for modulating immunoglobulin effector function

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9868-9872

2013

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IgE antibodies, FcεRIα, and IgE-mediated local anaphylaxis can limit snake venom toxicity

Journal of allergy and clinical immunology, 2016-01, Vol.137 (1), p.246-257.e11

2016

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Novel IgE crosslinking-induced luciferase expression method using human-rat chimeric IgE receptor-carrying mast cells

Journal of immunological methods, 2024-06, Vol.529, p.113682, Article 113682

2024

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Immunoglobulin E Signal Inhibition during Allergen Ingestion Leads to Reversal of Established Food Allergy and Induction of Regulatory T Cells

Immunity (Cambridge, Mass.), 2014-07, Vol.41 (1), p.141-151

2014

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Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases

Nature reviews. Immunology, 2022-05, Vol.22 (5), p.294-308

2022

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Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity

Nature communications, 2024-07, Vol.15 (1), p.5981-15, Article 5981

2024

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Estrogen increases the severity of anaphylaxis in female mice through enhanced endothelial nitric oxide synthase expression and nitric oxide production

Journal of allergy and clinical immunology, 2015-03, Vol.135 (3), p.729-736.e5

2015

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Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis

Journal of allergy and clinical immunology, 2017-02, Vol.139 (2), p.584-596.e10

2017

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Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells

Journal of allergy and clinical immunology, 2014-06, Vol.133 (6), p.1709-1719.e8

2014

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A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice

Nature communications, 2016-12, Vol.7 (1), p.13696-15, Article 13696

2016

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Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor

Nature (London), 2012-11, Vol.491 (7425), p.613-617

2012

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Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab

The Journal of biological chemistry, 2017-06, Vol.292 (24), p.9975-9987

2017

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A novel functional mast cell assay for the detection of allergies

Journal of allergy and clinical immunology, 2022-03, Vol.149 (3), p.1018-1030.e11

2022

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IgE, IgE Receptors and Anti-IgE Biologics: Protein Structures and Mechanisms of Action

Annual review of immunology, 2023-04, Vol.41 (1), p.255-275

2023

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THE BIOLOGY OF IGE AND THE BASIS OF ALLERGIC DISEASE

Annual review of immunology, 2003-01, Vol.21 (1), p.579-628

2003

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Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis

Journal of allergy and clinical immunology, 2015-08, Vol.136 (2), p.351-359.e1

2015

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Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases

Immunological reviews, 2011-07, Vol.242 (1), p.128-143

2011

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Changing the threshold—Signals and mechanisms of mast cell priming

Immunological reviews, 2018-03, Vol.282 (1), p.73-86

2018

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CD23/FcεRII: molecular multi-tasking

Clinical and experimental immunology, 2010-10, Vol.162 (1), p.12-23

2010

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FcεRI expression and IgE binding by dendritic cells and basophils in allergic rhinitis and upon allergen immunotherapy

Clinical and experimental allergy, 2018-08, Vol.48 (8), p.970-980

2018

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Variation of the group 5 grass pollen allergen content of airborne pollen in relation to geographic location and time in season

Journal of allergy and clinical immunology, 2015-07, Vol.136 (1), p.87-95.e6

2015

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Development of a Two-part Strategy to Identify a Therapeutic Human Bispecific Antibody That Inhibits IgE Receptor Signaling

The Journal of biological chemistry, 2010-07, Vol.285 (27), p.20850-20859

2010

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The role of immunoglobulin E and mast cells in hypertension

Cardiovascular research, 2022-11, Vol.118 (14), p.2985-2999

2022

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The effect of B-cell depletion therapy on serological evidence of B-cell and plasmablast activation in patients with rheumatoid arthritis over multiple cycles of rituximab treatment

Journal of autoimmunity, 2014-05, Vol.50, p.67-76

2014

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Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement

General mechanism for modulating immunoglobulin effector function

IgE antibodies, FcεRIα, and IgE-mediated local anaphylaxis can limit snake venom toxicity

Novel IgE crosslinking-induced luciferase expression method using human-rat chimeric IgE receptor-carrying mast cells

Immunoglobulin E Signal Inhibition during Allergen Ingestion Leads to Reversal of Established Food Allergy and Induction of Regulatory T Cells

Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases

Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity

Estrogen increases the severity of anaphylaxis in female mice through enhanced endothelial nitric oxide synthase expression and nitric oxide production

Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis

Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells

A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice

Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor

Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab

A novel functional mast cell assay for the detection of allergies

IgE, IgE Receptors and Anti-IgE Biologics: Protein Structures and Mechanisms of Action

THE BIOLOGY OF IGE AND THE BASIS OF ALLERGIC DISEASE

Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis

Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases

Changing the threshold—Signals and mechanisms of mast cell priming

CD23/FcεRII: molecular multi-tasking

FcεRI expression and IgE binding by dendritic cells and basophils in allergic rhinitis and upon allergen immunotherapy

Variation of the group 5 grass pollen allergen content of airborne pollen in relation to geographic location and time in season

Development of a Two-part Strategy to Identify a Therapeutic Human Bispecific Antibody That Inhibits IgE Receptor Signaling

The role of immunoglobulin E and mast cells in hypertension

The effect of B-cell depletion therapy on serological evidence of B-cell and plasmablast activation in patients with rheumatoid arthritis over multiple cycles of rituximab treatment

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