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Dacomitinib-induzierte purpuriforme Arzneimittelreaktion mit IQGAP1-Hochregulierung bei einer Patientin mit Adenokarzinom der Lunge

Journal der Deutschen Dermatologischen Gesellschaft, 2023-07, Vol.21 (7), p.795-797

2023

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7-Ketocholesterol Promotes Retinal Pigment Epithelium Senescence and Fibrosis of Choroidal Neovascularization via IQGAP1 Phosphorylation-Dependent Signaling

International journal of molecular sciences, 2023-06, Vol.24 (12), p.10276

2023

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N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling

International journal of molecular sciences, 2022-11, Vol.23 (23), p.14952

2022

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Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

Nature cell biology, 2020-12, Vol.22 (12), p.1460-1470

2020

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Higenamine Promotes Osteogenesis Via IQGAP1/SMAD4 Signaling Pathway and Prevents Age‐ and Estrogen‐Dependent Bone Loss in Mice

Journal of bone and mineral research, 2023-05, Vol.38 (5), p.775-791

2023

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The Ras GTPase‐activating‐like protein IQGAP1 bridges Gasdermin D to the ESCRT system to promote IL‐1β release via exosomes

The EMBO journal, 2023-01, Vol.42 (1), p.e110780-n/a

2023

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ATG9A protects the plasma membrane from programmed and incidental permeabilization

Nature cell biology, 2021-08, Vol.23 (8), p.846-858

2021

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Coordination of actin plus-end dynamics by IQGAP1, formin, and capping protein

The Journal of cell biology, 2024-09, Vol.223 (9)

2024

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Integrin β4 promotes DNA damage-related drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/RAC1

eLife, 2023-10, Vol.12

2023

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IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma

British journal of cancer, 2020-09, Vol.123 (7), p.1154-1163

2020

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A mode of cell adhesion and migration facilitated by CD44-dependent microtentacles

Proceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (21), p.11432-11443

2020

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SUMOylation of IQGAP1 promotes the development of colorectal cancer

Cancer letters, 2017-12, Vol.411, p.90-99

2017

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The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling

The Journal of cell biology, 2023-06, Vol.222 (6), p.1

2023

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AB0058 NOVEL BIOMARKERS FROM THE S100 PROTEIN FAMILY OF RHEUMATOID ARTHRITIS PROGRESSION WHICH CAN BE REGULATED BY EPIGENETIC DRUGS

Annals of the rheumatic diseases, 2023-06, Vol.82 (Suppl 1), p.1208-1208

2023

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Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

Nature communications, 2019-09, Vol.10 (1), p.3975-13, Article 3975

2019

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MIB1 upregulates IQGAP1 and promotes pancreatic cancer progression by inducing ST7 degradation

Molecular oncology, 2021-11, Vol.15 (11), p.3062-3075

2021

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Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction

Cancer research (Chicago, Ill.), 2017-08, Vol.77 (16), p.4328-4341

2017

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MicroRNA‐122 regulates polyploidization in the murine liver

Hepatology (Baltimore, Md.), 2016-08, Vol.64 (2), p.599-615

2016

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Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

Genome Biology, 2020-03, Vol.21 (1), p.80-80, Article 80

2020

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Purpuric drug eruptions induced by EGFR tyrosine kinase inhibitors are associated with IQGAP1‐mediated increase in vascular permeability

The Journal of pathology, 2020-04, Vol.250 (4), p.452-463

2020

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Dysregulated miR-124-3p in endometrial epithelial cells reduces endometrial receptivity by altering polarity and adhesion

Proceedings of the National Academy of Sciences - PNAS, 2024-10, Vol.121 (41), p.e2401071121

2024

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MicroRNA-124 inhibits hepatic stellate cells inflammatory cytokines secretion by targeting IQGAP1 through NF-κB pathway

International immunopharmacology, 2021-06, Vol.95, p.107520-107520, Article 107520

2021

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Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancer

Matrix biology, 2019-08, Vol.81, p.17-33

2019

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Unlike LGR4, LGR5 potentiates Wnt–β-catenin signaling without sequestering E3 ligases

Science signaling, 2020-12, Vol.13 (660)

2020

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The lectin Discoidin I acts in the cytoplasm to help assemble the contractile machinery

The Journal of cell biology, 2022-11, Vol.221 (11), p.1

2022

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Dacomitinib-induzierte purpuriforme Arzneimittelreaktion mit IQGAP1-Hochregulierung bei einer Patientin mit Adenokarzinom der Lunge

7-Ketocholesterol Promotes Retinal Pigment Epithelium Senescence and Fibrosis of Choroidal Neovascularization via IQGAP1 Phosphorylation-Dependent Signaling

N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling

Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

Higenamine Promotes Osteogenesis Via IQGAP1/SMAD4 Signaling Pathway and Prevents Age‐ and Estrogen‐Dependent Bone Loss in Mice

The Ras GTPase‐activating‐like protein IQGAP1 bridges Gasdermin D to the ESCRT system to promote IL‐1β release via exosomes

ATG9A protects the plasma membrane from programmed and incidental permeabilization

Coordination of actin plus-end dynamics by IQGAP1, formin, and capping protein

Integrin β4 promotes DNA damage-related drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/RAC1

IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma

A mode of cell adhesion and migration facilitated by CD44-dependent microtentacles

SUMOylation of IQGAP1 promotes the development of colorectal cancer

The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling

AB0058 NOVEL BIOMARKERS FROM THE S100 PROTEIN FAMILY OF RHEUMATOID ARTHRITIS PROGRESSION WHICH CAN BE REGULATED BY EPIGENETIC DRUGS

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

MIB1 upregulates IQGAP1 and promotes pancreatic cancer progression by inducing ST7 degradation

Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction

MicroRNA‐122 regulates polyploidization in the murine liver

Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

Purpuric drug eruptions induced by EGFR tyrosine kinase inhibitors are associated with IQGAP1‐mediated increase in vascular permeability

Dysregulated miR-124-3p in endometrial epithelial cells reduces endometrial receptivity by altering polarity and adhesion

MicroRNA-124 inhibits hepatic stellate cells inflammatory cytokines secretion by targeting IQGAP1 through NF-κB pathway

Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancer

Unlike LGR4, LGR5 potentiates Wnt–β-catenin signaling without sequestering E3 ligases

The lectin Discoidin I acts in the cytoplasm to help assemble the contractile machinery

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