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Established and Emerging Nucleic Acid Therapies for Familial Hypercholesterolemia

Circulation (New York, N.Y.), 2024-08, Vol.150 (9), p.724

2024

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Homozygous familial hypercholesterolemia: the impact of novel treatments

European journal of preventive cardiology, 2024-06, Vol.31 (8), p.1036

Kennedy, Cormac

2024

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Liver transplantation for the treatment of homozygous familial hypercholesterolaemia in an era of emerging lipid-lowering therapies

Internal medicine journal, 2014-06, Vol.44 (6), p.601-604

2014

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Lipid Disorders and Pregnancy

Endocrinology and metabolism clinics of North America, 2024-09, Vol.53 (3), p.483-495

2024

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Familial hypercholesterolemia in children and the importance of early treatment

Current opinion in lipidology, 2024-06, Vol.35 (3), p.126-132

2024

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Drug therapy of high-risk lipid abnormalities in children and adolescents : A scientific statement from the american heart association atherosclerosis, hypertension, and obesity in youth committee, council of cardiovascular disease in the young, with the council on cardiovascular nursing

Circulation (New York, N.Y.), 2007-04, Vol.115 (14), p.1948-1967

2007

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Factors Predicting Statin Initiation During Childhood in Familial Hypercholesterolemia: Importance of Genetic Diagnosis

The Journal of pediatrics, 2023-02, Vol.253, p.18-24.e2

2023

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New algorithms for treating homozygous familial hypercholesterolemia

Current opinion in lipidology, 2022-12, Vol.33 (6), p.326-335

2022

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Inhibition of Microsomal Triglyceride Transfer Protein in Familial Hypercholesterolemia

The New England journal of medicine, 2007-01, Vol.356 (2), p.148-156

2007

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Impact of evolocumab treatment on low-density lipoprotein cholesterol levels in heterozygous familial hypercholesterolemic patients withdrawing from regular apheresis

Atherosclerosis, 2017-10, Vol.265, p.225-230

2017

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Management of familial hypercholesterolemia in children and young adults: Consensus paper developed by a panel of lipidologists, cardiologists, paediatricians, nutritionists, gastroenterologists, general practitioners and a patient organization

Atherosclerosis, 2011-10, Vol.218 (2), p.272-280

2011

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The Impact of Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies with and without Apheresis on Platelet Aggregation in Familial Hypercholesterolemia

Cardiovascular drugs and therapy, 2024-10, Vol.38 (5), p.959-970

2024

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PCSK9 in context: A contemporary review of an important biological target for the prevention and treatment of atherosclerotic cardiovascular disease

Diabetes, obesity & metabolism, 2018-02, Vol.20 (2), p.270-282

2018

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Clinical decision support for familial hypercholesterolemia (CDS-FH): Rationale and design of a cluster randomized trial in primary care

The American heart journal, 2022-05, Vol.247, p.132-148

2022

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Is treating severe He FH so easy? A combined treatment between lipoprotein apheresis and PCSK9 inhibitors

Transfusion and apheresis science, 2021-12, Vol.60 (6), p.103258-103258, Article 103258

2021

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Screening and treatment of familial hypercholesterolemia in a French sample of ambulatory care patients: A retrospective longitudinal cohort study

PloS one, 2021-08, Vol.16 (8), p.e0255345

2021

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The Agenda for Familial Hypercholesterolemia: A Scientific Statement From the American Heart Association

Circulation (New York, N.Y.), 2015-12, Vol.132 (22), p.2167-2192

2015

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Management of homozygous familial hypercholesterolemia in real-world clinical practice: A report of 7 Italian patients treated in Rome with lomitapide and lipoprotein apheresis

Journal of clinical lipidology, 2016-07, Vol.10 (4), p.782-789

2016

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Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

Atherosclerosis, 2018-10, Vol.277, p.234-255

2018

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Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting PCSK9 in Nonhuman Primate and Mouse Models

Circulation (New York, N.Y.), 2023-01, Vol.147 (3), p.242-253

2023

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Familial hypercholesterolaemia: A global call to arms

Atherosclerosis, 2015-11, Vol.243 (1), p.257-259

2015

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Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

European heart journal, 2014-08, Vol.35 (32), p.2146-2157

2014

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Complex Phenotype of Hypercholesterolemia in a Family with Both ABCG8 and APOB Mutations

Portuguese journal of pediatrics (Online), 2021-11, Vol.52 (4)

2021

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International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia

Nature reviews cardiology, 2023-12, Vol.20 (12), p.845-869

2023

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Familial hypercholesterolaemia: evolving knowledge for designing adaptive models of care

Nature reviews cardiology, 2020-06, Vol.17 (6), p.360-377

2020

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Established and Emerging Nucleic Acid Therapies for Familial Hypercholesterolemia

Homozygous familial hypercholesterolemia: the impact of novel treatments

Liver transplantation for the treatment of homozygous familial hypercholesterolaemia in an era of emerging lipid-lowering therapies

Lipid Disorders and Pregnancy

Familial hypercholesterolemia in children and the importance of early treatment

Drug therapy of high-risk lipid abnormalities in children and adolescents : A scientific statement from the american heart association atherosclerosis, hypertension, and obesity in youth committee, council of cardiovascular disease in the young, with the council on cardiovascular nursing

Factors Predicting Statin Initiation During Childhood in Familial Hypercholesterolemia: Importance of Genetic Diagnosis

New algorithms for treating homozygous familial hypercholesterolemia

Inhibition of Microsomal Triglyceride Transfer Protein in Familial Hypercholesterolemia

Impact of evolocumab treatment on low-density lipoprotein cholesterol levels in heterozygous familial hypercholesterolemic patients withdrawing from regular apheresis

Management of familial hypercholesterolemia in children and young adults: Consensus paper developed by a panel of lipidologists, cardiologists, paediatricians, nutritionists, gastroenterologists, general practitioners and a patient organization

The Impact of Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies with and without Apheresis on Platelet Aggregation in Familial Hypercholesterolemia

PCSK9 in context: A contemporary review of an important biological target for the prevention and treatment of atherosclerotic cardiovascular disease

Clinical decision support for familial hypercholesterolemia (CDS-FH): Rationale and design of a cluster randomized trial in primary care

Is treating severe He FH so easy? A combined treatment between lipoprotein apheresis and PCSK9 inhibitors

Screening and treatment of familial hypercholesterolemia in a French sample of ambulatory care patients: A retrospective longitudinal cohort study

The Agenda for Familial Hypercholesterolemia: A Scientific Statement From the American Heart Association

Management of homozygous familial hypercholesterolemia in real-world clinical practice: A report of 7 Italian patients treated in Rome with lomitapide and lipoprotein apheresis

Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting PCSK9 in Nonhuman Primate and Mouse Models

Familial hypercholesterolaemia: A global call to arms

Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

Complex Phenotype of Hypercholesterolemia in a Family with Both ABCG8 and APOB Mutations

International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia

Familial hypercholesterolaemia: evolving knowledge for designing adaptive models of care

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