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Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy

Nature communications, 2021-04, Vol.12 (1), p.2425-2425, Article 2425

2021

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AminoBODIPY Conjugates for Targeted Drug Delivery Systems and Real-Time Monitoring of Drug Release

Molecular pharmaceutics, 2021-06, Vol.18 (6), p.2385-2396

2021

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A Phase 2a randomized, single-center, double-blind, placebo-controlled study to evaluate the safety and preliminary efficacy of oral iOWH032 against cholera diarrhea in a controlled human infection model

PLoS neglected tropical diseases, 2021-11, Vol.15 (11), p.e0009969-e0009969

2021

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Entrapment and release of quinoline derivatives using a hydrogel of a low molecular weight gelator

Journal of controlled release, 2004-06, Vol.97 (2), p.241-248

2004

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The effect of hydroxyquinoline-based gel on pessary-associated bacterial vaginosis: a multicenter randomized controlled trial

American journal of obstetrics and gynecology, 2015-11, Vol.213 (5), p.729.e1-729.e9

2015

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Novel multifunctional neuroprotective iron chelator‐monoamine oxidase inhibitor drugs for neurodegenerative diseases. In vivo selective brain monoamine oxidase inhibition and prevention of MPTP‐induced striatal dopamine depletion

Journal of neurochemistry, 2005-10, Vol.95 (1), p.79-88

2005

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Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation

Thrombosis and haemostasis, 2008-02, Vol.99 (2), p.343

2008

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The novel ETA receptor antagonist HJP-272 prevents cerebral microvascular hemorrhage in cerebral malaria and synergistically improves survival in combination with an artemisinin derivative

Life sciences (1973), 2012-10, Vol.91 (13-14), p.687-692

2012

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Prediction of a potentially effective dose in humans for BAY 60–5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically‐based pharmacokinetic modelling

British journal of clinical pharmacology, 2012-02, Vol.73 (2), p.219-231

2012

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Changes in the Vaginal Microenvironment as Related to Frequency of Pessary Removal

Female pelvic medicine & reconstructive surgery, 2018-03, Vol.24 (2), p.166

2018

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Additive Neuroprotective Effects of the Multifunctional Iron Chelator M30 with Enriched Diet in a Mouse Model of Amyotrophic Lateral Sclerosis

Neurotoxicity research, 2016-02, Vol.29 (2), p.208-217

2016

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The novel multi-target iron chelator, M30 modulates HIF-1α-related glycolytic genes and insulin signaling pathway in the frontal cortex of APP/PS1 Alzheimer's disease mice

Current Alzheimer research, 2014-02, Vol.11 (2), p.119

2014

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Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation

Thrombosis and haemostasis, 2007-03, Vol.97 (3), p.400

2007

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Y27, a novel derivative of 4-hydroxyquinoline-3-formamide, prevents the development of murine systemic lupus erythematosus-like diseases in MRL/lpr autoimmune mice and BDF1 hybrid mice

Arthritis research & therapy, 2012-11, Vol.14 (6), p.R235-R235

2012

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Effect of PSI‐697, a Novel P‐Selectin Inhibitor, on Platelet–Monocyte Aggregate Formation in Humans

Journal of the American Heart Association, 2013-02, Vol.2 (1), p.e006007-n/a

2013

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Characterization of new metabolites from in vivo biotransformation of 2-amino- 3-methylimidazo[4,5-f]quinoline in mouse by mass spectrometry

Journal of mass spectrometry., 2009-09, Vol.44 (9), p.1359-1368

2009

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Synthesis and Anti-HBV Activities Evaluation of New Ethyl 8-Imidazolylmethyl-7-hydroxyquinoline-3-carboxylate Derivatives in vitro

Archiv der Pharmazie (Weinheim), 2008-07, Vol.341 (7), p.446-452

2008

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A Thought Experiment in Contemporary Drug Development: Informed Bench‐to‐Bedside Strategies

Journal of the American Heart Association, 2013-02, Vol.2 (1), p.e000031-n/a

Becker, Richard C.

2013

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Low dose linomide in Type I juvenile diabetes of recent onset : a randomised placebo-controlled double blind trial

Diabetologia, 1998-09, Vol.41 (9), p.1040-1046

1998

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Amelioration of diabetes in nonobese diabetic mice with advanced disease by linomide-induced immunoregulation combined with Reg protein treatment

Endocrinology (Philadelphia), 1998-05, Vol.139 (5), p.2369-2374

1998

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Novel controllers of airway obstruction in COPD patients

Polski merkuriusz lekarski, 2011-01, Vol.30 (175), p.5

Płusa, Tadeusz

2011

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M30, a brain permeable multitarget neurorestorative drug in post nigrostriatal dopamine neuron lesion of parkinsonism animal models

Parkinsonism & related disorders, 2012-01, Vol.18 Suppl 1, p.S151-S154

Youdim, Moussa B H

2012

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Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs

Pulmonary pharmacology & therapeutics, 2007, Vol.20 (3), p.250

2007

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The Antiangiogenic Agent Linomide Inhibits the Growth Rate of von Hippel-Lindau Paraganglioma Xenografts to Mice

Clinical cancer research, 1999-11, Vol.5 (11), p.3669-3675

1999

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Effects of a Direct Injection of Liposoluble Iron into Rat Striatum. Importance of the Rate of Iron Delivery to Cells

Free radical research, 2003, Vol.37 (1), p.59-67

2003

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Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy

AminoBODIPY Conjugates for Targeted Drug Delivery Systems and Real-Time Monitoring of Drug Release

A Phase 2a randomized, single-center, double-blind, placebo-controlled study to evaluate the safety and preliminary efficacy of oral iOWH032 against cholera diarrhea in a controlled human infection model

Entrapment and release of quinoline derivatives using a hydrogel of a low molecular weight gelator

The effect of hydroxyquinoline-based gel on pessary-associated bacterial vaginosis: a multicenter randomized controlled trial

Novel multifunctional neuroprotective iron chelator‐monoamine oxidase inhibitor drugs for neurodegenerative diseases. In vivo selective brain monoamine oxidase inhibition and prevention of MPTP‐induced striatal dopamine depletion

Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation

The novel ETA receptor antagonist HJP-272 prevents cerebral microvascular hemorrhage in cerebral malaria and synergistically improves survival in combination with an artemisinin derivative

Prediction of a potentially effective dose in humans for BAY 60–5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically‐based pharmacokinetic modelling

Changes in the Vaginal Microenvironment as Related to Frequency of Pessary Removal

Additive Neuroprotective Effects of the Multifunctional Iron Chelator M30 with Enriched Diet in a Mouse Model of Amyotrophic Lateral Sclerosis

The novel multi-target iron chelator, M30 modulates HIF-1α-related glycolytic genes and insulin signaling pathway in the frontal cortex of APP/PS1 Alzheimer's disease mice

Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation

Y27, a novel derivative of 4-hydroxyquinoline-3-formamide, prevents the development of murine systemic lupus erythematosus-like diseases in MRL/lpr autoimmune mice and BDF1 hybrid mice

Effect of PSI‐697, a Novel P‐Selectin Inhibitor, on Platelet–Monocyte Aggregate Formation in Humans

Characterization of new metabolites from in vivo biotransformation of 2-amino- 3-methylimidazo[4,5-f]quinoline in mouse by mass spectrometry

Synthesis and Anti-HBV Activities Evaluation of New Ethyl 8-Imidazolylmethyl-7-hydroxyquinoline-3-carboxylate Derivatives in vitro

A Thought Experiment in Contemporary Drug Development: Informed Bench‐to‐Bedside Strategies

Low dose linomide in Type I juvenile diabetes of recent onset : a randomised placebo-controlled double blind trial

Amelioration of diabetes in nonobese diabetic mice with advanced disease by linomide-induced immunoregulation combined with Reg protein treatment

Novel controllers of airway obstruction in COPD patients

M30, a brain permeable multitarget neurorestorative drug in post nigrostriatal dopamine neuron lesion of parkinsonism animal models

Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs

The Antiangiogenic Agent Linomide Inhibits the Growth Rate of von Hippel-Lindau Paraganglioma Xenografts to Mice

Effects of a Direct Injection of Liposoluble Iron into Rat Striatum. Importance of the Rate of Iron Delivery to Cells

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