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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

Nature structural & molecular biology, 2020-04, Vol.27 (4), p.363-372

2020

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Local unfolding of the HSP27 monomer regulates chaperone activity

Nature communications, 2019-03, Vol.10 (1), p.1068-1068, Article 1068

2019

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HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

The Journal of biological chemistry, 2018-02, Vol.293 (8), p.2687-2700

2018

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Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Nature communications, 2018-11, Vol.9 (1), p.4563-11, Article 4563

2018

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The small heat shock protein Hsp27: Present understanding and future prospects

Journal of thermal biology, 2017-10, Vol.69, p.149-154

2017

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DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Molecular therapy, 2023-02, Vol.31 (2), p.471-486

2023

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Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response

International journal of molecular sciences, 2021-01, Vol.22 (2), p.513

2021

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Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell

Cell stress & chaperones, 2017-07, Vol.22 (4), p.517-529

Arrigo, André-Patrick

2017

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Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor‐dependent signaling pathways balance stalk vs. tip cell competence

The FASEB journal, 2017-11, Vol.31 (11), p.4720-4733

2017

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Hsp27 as a therapeutic target in cancers

Current drug targets, 2014-04, Vol.15 (4), p.423-431

2014

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Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases

Scientific reports, 2018-01, Vol.8 (1), p.688-15, Article 688

2018

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Induction of heat shock protein expression in SP2/0 transgenic cells and its effect on the production of monoclonal antibodies

PloS one, 2024-05, Vol.19 (5), p.e0300702-e0300702

2024

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Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation

Life sciences (1973), 2018-09, Vol.209, p.43-51

2018

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microRNA‐577 suppresses tumor growth and enhances chemosensitivity in colorectal cancer

Journal of biochemical and molecular toxicology, 2017-06, Vol.31 (6), p.n/a

2017

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Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats

Brain pathology (Zurich, Switzerland), 2017-11, Vol.27 (6), p.822-838

2017

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HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation

PloS one, 2016-10, Vol.11 (10), p.e0164285-e0164285

2016

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MicroRNA216b mediated downregulation of HSP27/STAT3/AKT signaling is critically involved in lambertianic acid induced apoptosis in human cervical cancers

Phytotherapy research, 2021-02, Vol.35 (2), p.898-907

2021

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The MK2/Hsp27 axis is a major survival mechanism for pancreatic ductal adenocarcinoma under genotoxic stress

Science translational medicine, 2021-12, Vol.13 (622), p.eabb5445

2021

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Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP

Cell stress & chaperones, 2022-03, Vol.27 (2), p.177-188

2022

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Phosphorylated Heat Shock Protein 27 Inhibits Lipopolysaccharide-Induced Inflammation in Thp1 Cells by Promoting TLR4 Endocytosis, Ubiquitination, and Degradation

Inflammation, 2019-10, Vol.42 (5), p.1788-1799

2019

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HSP27 protects against ferroptosis of glioblastoma cells

Human cell : official journal of Human Cell Research Society, 2022, Vol.35 (1), p.238-249

2022

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Knock down of heat shock protein 27 (HspB1) induces degradation of several putative client proteins

PloS one, 2012-01, Vol.7 (1), p.e29719

2012

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Schisandrin B ameliorates high-glucose-induced vascular endothelial cells injury by regulating the Noxa/Hsp27/NF-κB signaling pathway

Biochemistry and cell biology, 2019-12, Vol.97 (6), p.681-692

2019

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Extracellular HSP27 acts as a signaling molecule to activate NF-κB in macrophages

Cell stress & chaperones, 2013-01, Vol.18 (1), p.53-63

2013

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Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27

Biochimica et biophysica acta. General subjects, 2019-10, Vol.1863 (10), p.1536-1546

2019

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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

Local unfolding of the HSP27 monomer regulates chaperone activity

HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

The small heat shock protein Hsp27: Present understanding and future prospects

DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response

Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell

Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor‐dependent signaling pathways balance stalk vs. tip cell competence

Hsp27 as a therapeutic target in cancers

Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases

Induction of heat shock protein expression in SP2/0 transgenic cells and its effect on the production of monoclonal antibodies

Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation

microRNA‐577 suppresses tumor growth and enhances chemosensitivity in colorectal cancer

Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats

HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation

MicroRNA216b mediated downregulation of HSP27/STAT3/AKT signaling is critically involved in lambertianic acid induced apoptosis in human cervical cancers

The MK2/Hsp27 axis is a major survival mechanism for pancreatic ductal adenocarcinoma under genotoxic stress

Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP

Phosphorylated Heat Shock Protein 27 Inhibits Lipopolysaccharide-Induced Inflammation in Thp1 Cells by Promoting TLR4 Endocytosis, Ubiquitination, and Degradation

HSP27 protects against ferroptosis of glioblastoma cells

Knock down of heat shock protein 27 (HspB1) induces degradation of several putative client proteins

Schisandrin B ameliorates high-glucose-induced vascular endothelial cells injury by regulating the Noxa/Hsp27/NF-κB signaling pathway

Extracellular HSP27 acts as a signaling molecule to activate NF-κB in macrophages

Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27

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