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Drug-likeness approach of 2-aminopyrimidines as histamine H3 receptor ligands

Drug design, development and therapy, 2014-09, Vol.8 (default), p.1499-1513

2014

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Total Synthesis and Biological Evaluation of the Marine Bromopyrrole Alkaloid Dispyrin: Elucidation of Discrete Molecular Targets with Therapeutic Potential

Journal of natural products (Washington, D.C.), 2008-10, Vol.71 (10), p.1783-1786

2008

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An Efficient Multigram Synthesis of the Potent Histamine H3 Antagonist GT-2331 and the Reassessment of the Absolute Configuration

Journal of organic chemistry, 2004-01, Vol.69 (1), p.192-194

2004

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Search for new multi-target compounds against Alzheimer's disease among histamine H 3 receptor ligands

European journal of medicinal chemistry, 2020-01, Vol.185, p.111785

2020

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Naturally occurring and synthetic imidazoles: their chemistry and their biological activities

Current medicinal chemistry, 2006, Vol.13 (1), p.1-23

De Luca, Lidia

2006

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Luminescent Ruthenium Complexes for Theranostic Applications

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4906-4915

2014

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Squaramides: physical properties, synthesis and applications

Chemical Society reviews, 2011-05, Vol.40 (5), p.2330-2346

2011

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Special Issue: From Natural Polyphenols to Synthetic Bioactive Analogues

Molecules (Basel, Switzerland), 2020-06, Vol.25 (12), p.2772

Tringali, Corrado

2020

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Optimization and preclinical evaluation of novel histamine H 3 receptor ligands: Acetyl and propionyl phenoxyalkyl piperazine derivatives

Bioorganic & medicinal chemistry, 2018-12, Vol.26 (23-24), p.6056

2018

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Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H4 Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models

Journal of medicinal chemistry, 2008-10, Vol.51 (20), p.6547-6557

2008

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Anxiolytic and antidepressant-like activities of the novel and potent non-imidazole histamine H₃ receptor antagonist ST-1283

Drug design, development and therapy, 2014-05, Vol.8 (default), p.627-637

2014

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Structural modifications in the distal, regulatory region of histamine H 3 receptor antagonists leading to the identification of a potent anti-obesity agent

European journal of medicinal chemistry, 2021-03, Vol.213, p.113041

2021

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Cascade Transformations of 1-R-Ethynyl-9,10-anthraquinones with Amidines: Expanding Access to Isoaporphinoid Alkaloids

Molecules (Basel, Switzerland), 2021-11, Vol.26 (22), p.6883

2021

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Scutellarein derivatives with histamine H 3 receptor antagonism and cholinesterase inhibitory potency as multi target-directed ligands for possible Alzheimer's disease therapy

Bioorganic chemistry, 2024-10, Vol.151, p.107704

2024

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Synthesis and structure–activity relationship of tricyclic carboxylic acids as novel anti-histamines

Bioorganic & medicinal chemistry, 2011-05, Vol.19 (9), p.3005-3021

2011

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Synthesis and QSAR of Quinazoline Sulfonamides As Highly Potent Human Histamine H4 Receptor Inverse Agonists

Journal of medicinal chemistry, 2010-03, Vol.53 (6), p.2390-2400

2010

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Novel 1‑Phenyl-3-hydroxy-4-pyridinone Derivatives as Multifunctional Agents for the Therapy of Alzheimer’s Disease

ACS chemical neuroscience, 2016-01, Vol.7 (1), p.69-81

2016

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Synthesis of constrained benzocinnolinone analogues of CEP-26401 (irdabisant) as potent, selective histamine H3 receptor inverse agonists

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4198-4202

2012

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Searching for the Multi-Target-Directed Ligands against Alzheimer’s disease: Discovery of quinoxaline-based hybrid compounds with AChE, H3R and BACE 1 inhibitory activities

Bioorganic & medicinal chemistry, 2011-12, Vol.19 (23), p.7158-7167

2011

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Antinociceptive and anti-inflammatory effects of hydrazone derivatives and their possible mechanism of action in mice

PloS one, 2021-11, Vol.16 (11), p.e0258094

2021

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Synthesis and antihistamine evaluations of novel loratadine analogues

Bioorganic & medicinal chemistry letters, 2011-08, Vol.21 (15), p.4454-4456

2011

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Synthesis of Daidzein Glycosides, α-Tocopherol Glycosides, Hesperetin Glycosides by Bioconversion and Their Potential for Anti-Allergic Functional-Foods and Cosmetics

Molecules (Basel, Switzerland), 2019-08, Vol.24 (16), p.2975

2019

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Synthesis of glycosides of resveratrol, pterostilbene, and piceatannol, and their anti-oxidant, anti-allergic, and neuroprotective activities

Bioscience, biotechnology, and biochemistry, 2014, Vol.78 (7), p.1123-1128

2014

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Hybrid molecules based on an emodin scaffold. Synthesis and activity against SARS-CoV-2 and Plasmodium

Organic & biomolecular chemistry, 2023-09, Vol.21 (36), p.7382-7394

2023

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Synthesis and Antiallergic Activity of Dicoumarin Derivatives

Molecules (Basel, Switzerland), 2024-08, Vol.29 (16), p.3799

2024

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Drug-likeness approach of 2-aminopyrimidines as histamine H3 receptor ligands

Total Synthesis and Biological Evaluation of the Marine Bromopyrrole Alkaloid Dispyrin: Elucidation of Discrete Molecular Targets with Therapeutic Potential

An Efficient Multigram Synthesis of the Potent Histamine H3 Antagonist GT-2331 and the Reassessment of the Absolute Configuration

Search for new multi-target compounds against Alzheimer's disease among histamine H 3 receptor ligands

Naturally occurring and synthetic imidazoles: their chemistry and their biological activities

Luminescent Ruthenium Complexes for Theranostic Applications

Squaramides: physical properties, synthesis and applications

Special Issue: From Natural Polyphenols to Synthetic Bioactive Analogues

Optimization and preclinical evaluation of novel histamine H 3 receptor ligands: Acetyl and propionyl phenoxyalkyl piperazine derivatives

Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H4 Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models

Anxiolytic and antidepressant-like activities of the novel and potent non-imidazole histamine H₃ receptor antagonist ST-1283

Structural modifications in the distal, regulatory region of histamine H 3 receptor antagonists leading to the identification of a potent anti-obesity agent

Cascade Transformations of 1-R-Ethynyl-9,10-anthraquinones with Amidines: Expanding Access to Isoaporphinoid Alkaloids

Scutellarein derivatives with histamine H 3 receptor antagonism and cholinesterase inhibitory potency as multi target-directed ligands for possible Alzheimer's disease therapy

Synthesis and structure–activity relationship of tricyclic carboxylic acids as novel anti-histamines

Synthesis and QSAR of Quinazoline Sulfonamides As Highly Potent Human Histamine H4 Receptor Inverse Agonists

Novel 1‑Phenyl-3-hydroxy-4-pyridinone Derivatives as Multifunctional Agents for the Therapy of Alzheimer’s Disease

Synthesis of constrained benzocinnolinone analogues of CEP-26401 (irdabisant) as potent, selective histamine H3 receptor inverse agonists

Searching for the Multi-Target-Directed Ligands against Alzheimer’s disease: Discovery of quinoxaline-based hybrid compounds with AChE, H3R and BACE 1 inhibitory activities

Antinociceptive and anti-inflammatory effects of hydrazone derivatives and their possible mechanism of action in mice

Synthesis and antihistamine evaluations of novel loratadine analogues

Synthesis of Daidzein Glycosides, α-Tocopherol Glycosides, Hesperetin Glycosides by Bioconversion and Their Potential for Anti-Allergic Functional-Foods and Cosmetics

Synthesis of glycosides of resveratrol, pterostilbene, and piceatannol, and their anti-oxidant, anti-allergic, and neuroprotective activities

Hybrid molecules based on an emodin scaffold. Synthesis and activity against SARS-CoV-2 and Plasmodium

Synthesis and Antiallergic Activity of Dicoumarin Derivatives

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