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Discovery of a Cyclic Boronic Acid β‑Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3682-3692

2015

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Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations

Drugs (New York, N.Y.), 2018, Vol.78 (1), p.65-98

2018

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Meropenem/vaborbactam: a next generation β-lactam β-lactamase inhibitor combination

Expert review of anti-infective therapy, 2020-07, Vol.18 (7), p.643-655

2020

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Pharmacokinetics/Pharmacodynamics of Vaborbactam, a Novel Beta-Lactamase Inhibitor, in Combination with Meropenem

Antimicrobial agents and chemotherapy, 2019-01, Vol.63 (1)

2019

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Comparative Antimalarial Activities and ADME Profiles of Ozonides (1,2,4-trioxolanes) OZ277, OZ439, and Their 1,2-Dioxolane, 1,2,4-Trioxane, and 1,2,4,5-Tetraoxane Isosteres

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2547-2555

2013

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Effects of KPC Variant and Porin Genotype on the In Vitro Activity of Meropenem-Vaborbactam against Carbapenem-Resistant Enterobacteriaceae

Antimicrobial agents and chemotherapy, 2019-03, Vol.63 (3)

2019

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In Vitro Activity of Meropenem-Vaborbactam against Clinical Isolates of KPC-Positive Enterobacteriaceae

Antimicrobial agents and chemotherapy, 2018-01, Vol.62 (1)

2018

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A bioorthogonally activatable photosensitiser for site-specific photodynamic therapy

Chemical communications (Cambridge, England), 2020-01, Vol.56 (7), p.178-181

2020

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Activity of Meropenem Combined with RPX7009, a Novel β-Lactamase Inhibitor, against Gram-Negative Clinical Isolates in New York City

Antimicrobial agents and chemotherapy, 2015-08, Vol.59 (8), p.4856-4860

2015

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Antitubercular Bis-Substituted Cyclam Derivatives: Structure–Activity Relationships and in Vivo Studies

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3595-3608

2018

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Identification of an antimalarial synthetic trioxolane drug development candidate

Nature, 2004-08, Vol.430 (7002), p.900-904

2004

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Advances in targeted alpha therapy for prostate cancer

Annals of oncology, 2019-11, Vol.30 (11), p.1728-1739

2019

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Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides

Antimicrobial agents and chemotherapy, 2019-01, Vol.63 (1)

2019

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Novel therapies are changing treatment paradigms in metastatic prostate cancer

Journal of hematology and oncology, 2020-10, Vol.13 (1), p.144-144, Article 144

2020

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Biochemical Activity of Vaborbactam

Antimicrobial agents and chemotherapy, 2020-01, Vol.64 (2)

2020

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Stagonolides J and K and Stagochromene A, Two New Natural Substituted Nonenolides and a New Disubstituted Chromene-4,5-dione Isolated from Stagonospora cirsii S‑47 Proposed for the Biocontrol of Sonchus arvensis

Journal of agricultural and food chemistry, 2019-11, Vol.67 (47), p.13040-13050

2019

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The Structure−Activity Relationship of the Antimalarial Ozonide Arterolane (OZ277)

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.481-491

2010

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Synthesis and in vitro antitumor activity of water soluble sulfonate- and ester-functionalized silver(I) N-heterocyclic carbene complexes

Journal of inorganic biochemistry, 2013-12, Vol.129, p.135-144

2013

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Head-to-Head Comparison of Fibroblast Activation Protein Inhibitors (FAPI) Radiotracers versus [ 18 F]F-FDG in Oncology: A Systematic Review

International journal of molecular sciences, 2021-10, Vol.22 (20), p.11192

2021

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Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice

PloS one, 2016-03, Vol.11 (3), p.e0151765

2016

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Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane

Journal of medicinal chemistry, 2017-07, Vol.60 (14), p.6400-6407

2017

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A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

The Journal of neuroscience, 2005-07, Vol.25 (27), p.6401-6408

2005

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Activity of ceftazidime/avibactam, meropenem/vaborbactam and imipenem/relebactam against carbapenemase-negative carbapenem-resistant Enterobacterales isolates from US hospitals

International journal of antimicrobial agents, 2021-11, Vol.58 (5), p.106439-106439, Article 106439

2021

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Development of a Ga-68 labeled PET tracer with short linker for prostate-specific membrane antigen (PSMA) targeting

Bioorganic & medicinal chemistry, 2018-05, Vol.26 (9), p.2501-2507

2018

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Discovery of a Cyclic Boronic Acid β‑Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases

Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations

Meropenem/vaborbactam: a next generation β-lactam β-lactamase inhibitor combination

Pharmacokinetics/Pharmacodynamics of Vaborbactam, a Novel Beta-Lactamase Inhibitor, in Combination with Meropenem

Comparative Antimalarial Activities and ADME Profiles of Ozonides (1,2,4-trioxolanes) OZ277, OZ439, and Their 1,2-Dioxolane, 1,2,4-Trioxane, and 1,2,4,5-Tetraoxane Isosteres

Effects of KPC Variant and Porin Genotype on the In Vitro Activity of Meropenem-Vaborbactam against Carbapenem-Resistant Enterobacteriaceae

In Vitro Activity of Meropenem-Vaborbactam against Clinical Isolates of KPC-Positive Enterobacteriaceae

A bioorthogonally activatable photosensitiser for site-specific photodynamic therapy

Activity of Meropenem Combined with RPX7009, a Novel β-Lactamase Inhibitor, against Gram-Negative Clinical Isolates in New York City

Antitubercular Bis-Substituted Cyclam Derivatives: Structure–Activity Relationships and in Vivo Studies

Identification of an antimalarial synthetic trioxolane drug development candidate

Advances in targeted alpha therapy for prostate cancer

Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides

Novel therapies are changing treatment paradigms in metastatic prostate cancer

Biochemical Activity of Vaborbactam

Stagonolides J and K and Stagochromene A, Two New Natural Substituted Nonenolides and a New Disubstituted Chromene-4,5-dione Isolated from Stagonospora cirsii S‑47 Proposed for the Biocontrol of Sonchus arvensis

The Structure−Activity Relationship of the Antimalarial Ozonide Arterolane (OZ277)

Synthesis and in vitro antitumor activity of water soluble sulfonate- and ester-functionalized silver(I) N-heterocyclic carbene complexes

Head-to-Head Comparison of Fibroblast Activation Protein Inhibitors (FAPI) Radiotracers versus [ 18 F]F-FDG in Oncology: A Systematic Review

Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice

Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane

Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury

A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

Activity of ceftazidime/avibactam, meropenem/vaborbactam and imipenem/relebactam against carbapenemase-negative carbapenem-resistant Enterobacterales isolates from US hospitals

Development of a Ga-68 labeled PET tracer with short linker for prostate-specific membrane antigen (PSMA) targeting

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