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Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

Nature (London), 2011-07, Vol.475 (7356), p.390-393

2011

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The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation

Molecular cell, 2016-04, Vol.62 (1), p.79-91

2016

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Conversion of hepatoma cells to hepatocyte-like cells by defined hepatocyte nuclear factors

Cell research, 2019-02, Vol.29 (2), p.124-135

2019

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FOXA2 controls the cis‐regulatory networks of pancreatic cancer cells in a differentiation grade‐specific manner

The EMBO journal, 2019-10, Vol.38 (20), p.e102161-n/a

2019

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Liver‐enriched transcription factors regulate MicroRNA‐122 that targets CUTL1 during liver development

Hepatology (Baltimore, Md.), 2010-10, Vol.52 (4), p.1431-1442

2010

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Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2)

Toxicology and applied pharmacology, 2009-02, Vol.234 (3), p.281-292

2009

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Conversion of Fibroblasts to Hepatocytes In Vitro

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1905, p.93

2019

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A Review of Functional Characterization of Single Amino Acid Change Mutations in HNF Transcription Factors in MODY Pathogenesis

The Protein Journal, 2021-06, Vol.40 (3), p.348-360

2021

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Hepatic HNF1 transcription factors control the induction of PCSK9 mediated by rosuvastatin in normolipidemic hamsters

International journal of molecular medicine, 2017-03, Vol.39 (3), p.749-756

2017

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Promotion of the efficient metabolic maturation of human pluripotent stem cell-derived hepatocytes by correcting specification defects

Cell research, 2013-01, Vol.23 (1), p.157-161

2013

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Hepatocyte nuclear factors 1α/4α and forkhead box A2 regulate the solute carrier 2A2 (Slc2a2) gene expression in the liver and kidney of diabetic rats

Life sciences (1973), 2013-11, Vol.93 (22), p.805-813

2013

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Monogenic diabetes: a gateway to precision medicine in diabetes

The Journal of clinical investigation, 2021-02, Vol.131 (3)

2021

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Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

Nature (London), 2011-07, Vol.475 (7356), p.386-389

2011

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Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma

PloS one, 2014-09, Vol.9 (9), p.e107246

2014

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Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function

Biochimica et biophysica acta, 2016-04, Vol.1859 (4), p.591-598

2016

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Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells

FEBS letters, 2015-04, Vol.589 (10), p.1112-1118

2015

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Tbx3 promotes liver bud expansion during mouse development by suppression of cholangiocyte differentiation

Hepatology (Baltimore, Md.), 2009-03, Vol.49 (3), p.969-978

2009

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Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction

Journal of hepatology, 2012-09, Vol.57 (3), p.628-636

2012

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Impaired hepatic glucose metabolism and liver-α-cell axis in mice with liver-specific ablation of the Hepatocyte Nuclear Factor 4α (Hnf4a) gene

Metabolism, clinical and experimental, 2023-02, Vol.139, p.155371-155371, Article 155371

2023

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HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes

Nature communications, 2024-06, Vol.15 (1), p.4288-21, Article 4288

2024

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Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq

Genome Biology, 2009-01, Vol.10 (11), p.R129-R129, Article R129

2009

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Computational analyses of type 2 diabetes‐associated loci identified by genome‐wide association studies

Journal of diabetes, 2017-04, Vol.9 (4), p.362-377

2017

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HNF4A modulates glucocorticoid action in the liver

Cell reports (Cambridge), 2022-04, Vol.39 (3), p.110697-110697, Article 110697

2022

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Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

Diabetes care, 2017-08, Vol.40 (8), p.1017-1025

2017

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DNA methylation patterns of transcription factor binding regions characterize their functional and evolutionary contexts

Genome Biology, 2024-06, Vol.25 (1), p.146-22

2024

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Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation

Conversion of hepatoma cells to hepatocyte-like cells by defined hepatocyte nuclear factors

FOXA2 controls the cis‐regulatory networks of pancreatic cancer cells in a differentiation grade‐specific manner

Liver‐enriched transcription factors regulate MicroRNA‐122 that targets CUTL1 during liver development

Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2)

Conversion of Fibroblasts to Hepatocytes In Vitro

A Review of Functional Characterization of Single Amino Acid Change Mutations in HNF Transcription Factors in MODY Pathogenesis

Hepatic HNF1 transcription factors control the induction of PCSK9 mediated by rosuvastatin in normolipidemic hamsters

Promotion of the efficient metabolic maturation of human pluripotent stem cell-derived hepatocytes by correcting specification defects

Hepatocyte nuclear factors 1α/4α and forkhead box A2 regulate the solute carrier 2A2 (Slc2a2) gene expression in the liver and kidney of diabetic rats

Monogenic diabetes: a gateway to precision medicine in diabetes

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma

Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function

Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells

Tbx3 promotes liver bud expansion during mouse development by suppression of cholangiocyte differentiation

Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction

Impaired hepatic glucose metabolism and liver-α-cell axis in mice with liver-specific ablation of the Hepatocyte Nuclear Factor 4α (Hnf4a) gene

HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes

Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq

Computational analyses of type 2 diabetes‐associated loci identified by genome‐wide association studies

HNF4A modulates glucocorticoid action in the liver

Population-Based Assessment of a Biomarker-Based Screening Pathway to Aid Diagnosis of Monogenic Diabetes in Young-Onset Patients

DNA methylation patterns of transcription factor binding regions characterize their functional and evolutionary contexts

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