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The influenza virus hemagglutinin head evolves faster than the stalk domain

Scientific reports, 2018-07, Vol.8 (1), p.10432-14, Article 10432

2018

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Virus‐Mimicking Cell Membrane‐Coated Nanoparticles for Cytosolic Delivery of mRNA

Angewandte Chemie International Edition, 2022-01, Vol.61 (2), p.e202113671-n/a

International ed. in English, 2022

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De novo design of protein structure and function with RFdiffusion

Nature (London), 2023-08, Vol.620 (7976), p.1089-1100

2023

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Hemagglutinin Stability Regulates H1N1 Influenza Virus Replication and Pathogenicity in Mice by Modulating Type I Interferon Responses in Dendritic Cells

Journal of virology, 2020-01, Vol.94 (3)

2020

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Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity

Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (41), p.25759-25770

2020

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Human Influenza Virus Hemagglutinins Contain Conserved Oligomannose N-Linked Glycans Allowing Potent Neutralization by Lectins

Cell host & microbe, 2020-05, Vol.27 (5), p.725-735.e5

2020

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Influenza A Virus Hemagglutinin–Neuraminidase–Receptor Balance: Preserving Virus Motility

Trends in microbiology (Regular ed.), 2020-01, Vol.28 (1), p.57-67

2020

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Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity

PLoS pathogens, 2020-02, Vol.16 (2), p.e1008362-e1008362

2020

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Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope

Cell host & microbe, 2019-06, Vol.25 (6), p.827-835.e6

2019

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Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

Science (American Association for the Advancement of Science), 2010-04, Vol.328 (5976), p.357-360

2010

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Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (47), p.12578-12583

2017

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Universal Influenza Virus Vaccines That Target the Conserved Hemagglutinin Stalk and Conserved Sites in the Head Domain

The Journal of infectious diseases, 2019-04, Vol.219 (Supplement_1), p.S62-S67

2019

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Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (35), p.E8276-E8285

2018

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A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes

Science (American Association for the Advancement of Science), 2022-11, Vol.378 (6622), p.899-904

2022

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Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (1), p.168-173

2018

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A Perspective on the Structural and Functional Constraints for Immune Evasion: Insights from Influenza Virus

Journal of molecular biology, 2017-08, Vol.429 (17), p.2694-2709

2017

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Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells

Journal of virology, 2021-09, Vol.95 (20), p.e0090621-e0090621

2021

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Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets

Journal of Virology, 2014-03, Vol.88 (6), p.3432-3442

2014

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Structural transitions in influenza haemagglutinin at membrane fusion pH

Nature (London), 2020-07, Vol.583 (7814), p.150-153

2020

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Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.17040-17045

2012

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A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human‐type receptors

EMBO molecular medicine, 2017-09, Vol.9 (9), p.1314-1325

2017

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Chimeric Hemagglutinin Constructs Induce Broad Protection against Influenza B Virus Challenge in the Mouse Model

Journal of virology, 2017-06, Vol.91 (12)

2017

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Hemagglutinin Stalk-Reactive Antibodies Interfere with Influenza Virus Neuraminidase Activity by Steric Hindrance

Journal of virology, 2019-02, Vol.93 (4)

2019

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The Stabilities of the Soluble Ectodomain and Fusion Peptide Hairpins of the Influenza Virus Hemagglutinin Subunit II Protein Are Positively Correlated with Membrane Fusion

Biochemistry (Easton), 2018-09, Vol.57 (37), p.5480-5493

2018

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Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans

Nature communications, 2020-09, Vol.11 (1), p.4646-4646, Article 4646

2020

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The influenza virus hemagglutinin head evolves faster than the stalk domain

Virus‐Mimicking Cell Membrane‐Coated Nanoparticles for Cytosolic Delivery of mRNA

De novo design of protein structure and function with RFdiffusion

Hemagglutinin Stability Regulates H1N1 Influenza Virus Replication and Pathogenicity in Mice by Modulating Type I Interferon Responses in Dendritic Cells

Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity

Human Influenza Virus Hemagglutinins Contain Conserved Oligomannose N-Linked Glycans Allowing Potent Neutralization by Lectins

Influenza A Virus Hemagglutinin–Neuraminidase–Receptor Balance: Preserving Virus Motility

Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity

Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains

Universal Influenza Virus Vaccines That Target the Conserved Hemagglutinin Stalk and Conserved Sites in the Head Domain

Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants

A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes

Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

A Perspective on the Structural and Functional Constraints for Immune Evasion: Insights from Influenza Virus

Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells

Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets

Structural transitions in influenza haemagglutinin at membrane fusion pH

Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity

A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human‐type receptors

Chimeric Hemagglutinin Constructs Induce Broad Protection against Influenza B Virus Challenge in the Mouse Model

Hemagglutinin Stalk-Reactive Antibodies Interfere with Influenza Virus Neuraminidase Activity by Steric Hindrance

The Stabilities of the Soluble Ectodomain and Fusion Peptide Hairpins of the Influenza Virus Hemagglutinin Subunit II Protein Are Positively Correlated with Membrane Fusion

Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans

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