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HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy

International journal of oncology, 2014-07, Vol.45 (1), p.18-30

2014

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HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

The Journal of biological chemistry, 2018-02, Vol.293 (8), p.2687-2700

2018

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HSPB1 as a novel regulator of ferroptotic cancer cell death

Oncogene, 2015-11, Vol.34 (45), p.5617-5625

2015

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Heat Shock Proteins Promote Cancer: It's a Protection Racket

Trends in biochemical sciences (Amsterdam. Regular ed.), 2016-04, Vol.41 (4), p.311-323

2016

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Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death

The international journal of biochemistry & cell biology, 2012-10, Vol.44 (10), p.1622-1631

2012

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Local unfolding of the HSP27 monomer regulates chaperone activity

Nature communications, 2019-03, Vol.10 (1), p.1068-1068, Article 1068

2019

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The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

The Journal of biological chemistry, 2017-01, Vol.292 (2), p.672-684

2017

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Distinct induction pathways of heat shock protein 27 in human keratinocytes: Heat stimulation or capsaicin through phosphorylation of heat shock factor 1 at serine 326 and/or suppression of ΔNp63

Biochemical and biophysical research communications, 2024-05, Vol.708, p.149817-149817, Article 149817

2024

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Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Nature communications, 2018-11, Vol.9 (1), p.4563-11, Article 4563

2018

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The long noncoding RNA NEAT1 and nuclear paraspeckles are up-regulated by the transcription factor HSF1 in the heat shock response

The Journal of biological chemistry, 2018-12, Vol.293 (49), p.18965-18976

2018

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Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell

Cell stress & chaperones, 2017-07, Vol.22 (4), p.517-529

Arrigo, André-Patrick

2017

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Apoptosis, autophagy and atherosclerosis: Relationships and the role of Hsp27

Pharmacological research, 2021-04, Vol.166, p.105169-105169, Article 105169

2021

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Induction of heat shock protein expression in SP2/0 transgenic cells and its effect on the production of monoclonal antibodies

PloS one, 2024-05, Vol.19 (5), p.e0300702-e0300702

2024

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The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity

The Journal of biological chemistry, 2018-03, Vol.293 (12), p.4486-4497

2018

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Characterization of heat shock protein 27 in extracellular vesicles: a potential anti‐inflammatory therapy

The FASEB journal, 2019-02, Vol.33 (2), p.1617-1630

2019

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Small Heat-shock Proteins Prevent α-Synuclein Aggregation via Transient Interactions and Their Efficacy Is Affected by the Rate of Aggregation

The Journal of biological chemistry, 2016-10, Vol.291 (43), p.22618-22629

2016

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Heat shock proteins and kidney disease: perspectives of HSP therapy

Cell stress & chaperones, 2017-05, Vol.22 (3), p.319-343

2017

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Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3

Journal of molecular biology, 2018-09, Vol.430 (18), p.3297-3310

2018

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Small Heat Shock Proteins and Human Neurodegenerative Diseases

Biochemistry (Moscow), 2019-11, Vol.84 (11), p.1256-1267

2019

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Plasma Exosomes Protect the Myocardium From Ischemia-Reperfusion Injury

Journal of the American College of Cardiology, 2015-04, Vol.65 (15), p.1525-1536

2015

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Cellular functions of heat shock protein 20 (HSPB6) in cancer: A review

Cellular signalling, 2023-12, Vol.112, p.110928-110928, Article 110928

2023

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DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Molecular therapy, 2023-02, Vol.31 (2), p.471-486

2023

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Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.E1243-E1252

2017

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The small heat shock protein Hsp27: Present understanding and future prospects

Journal of thermal biology, 2017-10, Vol.69, p.149-154

2017

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Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor‐dependent signaling pathways balance stalk vs. tip cell competence

The FASEB journal, 2017-11, Vol.31 (11), p.4720-4733

2017

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HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy

HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

HSPB1 as a novel regulator of ferroptotic cancer cell death

Heat Shock Proteins Promote Cancer: It's a Protection Racket

Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death

Local unfolding of the HSP27 monomer regulates chaperone activity

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

Distinct induction pathways of heat shock protein 27 in human keratinocytes: Heat stimulation or capsaicin through phosphorylation of heat shock factor 1 at serine 326 and/or suppression of ΔNp63

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

The long noncoding RNA NEAT1 and nuclear paraspeckles are up-regulated by the transcription factor HSF1 in the heat shock response

Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell

Apoptosis, autophagy and atherosclerosis: Relationships and the role of Hsp27

Induction of heat shock protein expression in SP2/0 transgenic cells and its effect on the production of monoclonal antibodies

The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity

Characterization of heat shock protein 27 in extracellular vesicles: a potential anti‐inflammatory therapy

Small Heat-shock Proteins Prevent α-Synuclein Aggregation via Transient Interactions and Their Efficacy Is Affected by the Rate of Aggregation

Heat shock proteins and kidney disease: perspectives of HSP therapy

Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3

Small Heat Shock Proteins and Human Neurodegenerative Diseases

Plasma Exosomes Protect the Myocardium From Ischemia-Reperfusion Injury

Cellular functions of heat shock protein 20 (HSPB6) in cancer: A review

DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury

The small heat shock protein Hsp27: Present understanding and future prospects

Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor‐dependent signaling pathways balance stalk vs. tip cell competence

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