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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

Nature structural & molecular biology, 2020-04, Vol.27 (4), p.363

2020

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DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Molecular therapy, 2023-02, Vol.31 (2), p.471-486

2023

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The small heat shock protein Hsp27: Present understanding and future prospects

Journal of thermal biology, 2017-10, Vol.69, p.149-154

2017

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Local unfolding of the HSP27 monomer regulates chaperone activity

Nature communications, 2019-03, Vol.10 (1), p.1068-1068, Article 1068

2019

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Characterization of heat shock protein 27 in extracellular vesicles: a potential anti‐inflammatory therapy

The FASEB journal, 2019-02, Vol.33 (2), p.1617-1630

2019

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HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

The Journal of biological chemistry, 2018-02, Vol.293 (8), p.2687-2700

2018

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Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response

International journal of molecular sciences, 2021-01, Vol.22 (2), p.513

2021

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The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

The Journal of biological chemistry, 2017-01, Vol.292 (2), p.672-684

2017

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Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell

Cell stress & chaperones, 2017-07, Vol.22 (4), p.517-529

Arrigo, André-Patrick

2017

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microRNA‐577 suppresses tumor growth and enhances chemosensitivity in colorectal cancer

Journal of biochemical and molecular toxicology, 2017-06, Vol.31 (6), p.n/a

2017

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Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Nature communications, 2018-11, Vol.9 (1), p.4563-11, Article 4563

2018

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Phosphorylated Heat Shock Protein 27 Inhibits Lipopolysaccharide-Induced Inflammation in Thp1 Cells by Promoting TLR4 Endocytosis, Ubiquitination, and Degradation

Inflammation, 2019-10, Vol.42 (5), p.1788-1799

2019

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Hsp27 as a therapeutic target in cancers

Current drug targets, 2014-04, Vol.15 (4), p.423

2014

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Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP

Cell stress & chaperones, 2022-03, Vol.27 (2), p.177-188

2022

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HSP27 protects against ferroptosis of glioblastoma cells

Human cell : official journal of Human Cell Research Society, 2022, Vol.35 (1), p.238-249

2022

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Untangling the complexity of heat shock protein 27 in cancer and metastasis

Archives of biochemistry and biophysics, 2023-03, Vol.736, p.109537-109537, Article 109537

2023

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The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis

Journal of biomedical science, 2023-01, Vol.30 (1), p.2-2, Article 2

2023

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Small molecule heat shock protein 27 inhibitor J2 decreases ovarian cancer cell proliferation via induction of apoptotic pathways

Medical oncology (Northwood, London, England), 2023-07, Vol.40 (9), p.250-250, Article 250

2023

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MicroRNA216b mediated downregulation of HSP27/STAT3/AKT signaling is critically involved in lambertianic acid induced apoptosis in human cervical cancers

Phytotherapy research, 2021-02, Vol.35 (2), p.898-907

2021

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Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death

The international journal of biochemistry & cell biology, 2012-10, Vol.44 (10), p.1622-1631

2012

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Schisandrin B ameliorates high-glucose-induced vascular endothelial cells injury by regulating the Noxa/Hsp27/NF-κB signaling pathway

Biochemistry and cell biology, 2019-12, Vol.97 (6), p.681

2019

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HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy

International journal of oncology, 2014-07, Vol.45 (1), p.18-30

2014

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Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation

Stem cell reviews and reports, 2022-02, Vol.18 (2), p.839-852

2022

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HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation

PloS one, 2016-10, Vol.11 (10), p.e0164285-e0164285

2016

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MS4A3-HSP27 target pathway reveals potential for haematopoietic disorder treatment in alimentary toxic aleukia

Cell biology and toxicology, 2023-02, Vol.39 (1), p.201-216

2023

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Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation

DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

The small heat shock protein Hsp27: Present understanding and future prospects

Local unfolding of the HSP27 monomer regulates chaperone activity

Characterization of heat shock protein 27 in extracellular vesicles: a potential anti‐inflammatory therapy

HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell

microRNA‐577 suppresses tumor growth and enhances chemosensitivity in colorectal cancer

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Phosphorylated Heat Shock Protein 27 Inhibits Lipopolysaccharide-Induced Inflammation in Thp1 Cells by Promoting TLR4 Endocytosis, Ubiquitination, and Degradation

Hsp27 as a therapeutic target in cancers

Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP

HSP27 protects against ferroptosis of glioblastoma cells

Untangling the complexity of heat shock protein 27 in cancer and metastasis

The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis

Small molecule heat shock protein 27 inhibitor J2 decreases ovarian cancer cell proliferation via induction of apoptotic pathways

MicroRNA216b mediated downregulation of HSP27/STAT3/AKT signaling is critically involved in lambertianic acid induced apoptosis in human cervical cancers

Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death

Schisandrin B ameliorates high-glucose-induced vascular endothelial cells injury by regulating the Noxa/Hsp27/NF-κB signaling pathway

HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy

Downregulated Calcium-Binding Protein S100A16 and HSP27 in Placenta-Derived Multipotent Cells Induce Functional Astrocyte Differentiation

HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation

MS4A3-HSP27 target pathway reveals potential for haematopoietic disorder treatment in alimentary toxic aleukia

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