UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease

PLoS genetics, 2020-10, Vol.16 (10), p.e1009009

2020

Volltextzugriff (PDF)

Elucidating the druggable interface of protein–protein interactions using fragment docking and coevolutionary analysis

Proceedings of the National Academy of Sciences - PNAS, 2016-12, Vol.113 (50), p.E8051-E8058

2016

Volltextzugriff (PDF)

Improving Viral Protease Inhibitors to Counter Drug Resistance

Trends in microbiology (Regular ed.), 2016-07, Vol.24 (7), p.547-557

2016

Volltextzugriff (PDF)

Transition States, Analogues, and Drug Development

ACS chemical biology, 2013-01, Vol.8 (1), p.71-81

Schramm, Vern L

2013

Volltextzugriff (PDF)

Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

Accounts of chemical research, 2008-01, Vol.41 (1), p.78-86

2008

Volltextzugriff (PDF)

A new structural theme in C2-symmetric HIV-1 protease inhibitors : ortho-Substituted P1/P1' side chains

Bioorganic & medicinal chemistry, 2006-08, Vol.14 (15), p.5303-5315

2006

Volltextzugriff (PDF)

Hydration Structure and Dynamics of Inhibitor-Bound HIV‑1 Protease

Journal of chemical theory and computation, 2018-05, Vol.14 (5), p.2784-2796

2018

Volltextzugriff (PDF)

Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization

Journal of medicinal chemistry, 2006-12, Vol.49 (26), p.7697-7710

2006

Volltextzugriff (PDF)

Complex Patterns of Protease Inhibitor Resistance among Antiretroviral Treatment-Experienced HIV-2 Patients from Senegal: Implications for Second-Line Therapy

Antimicrobial Agents and Chemotherapy, 2013-06, Vol.57 (6), p.2751-2760

2013

Volltextzugriff (PDF)

New anti-HIV agents and targets

Medicinal research reviews, 2002-11, Vol.22 (6), p.531-565

Clercq, Erik De

2002

Volltextzugriff (PDF)

Highly Potent HIV‑1 Protease Inhibitors with Novel Tricyclic P2 Ligands: Design, Synthesis, and Protein–Ligand X‑ray Studies

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6792-6802

2013

Volltextzugriff (PDF)

Exploration of the effect of sequence variations located inside the binding pocket of HIV-1 and HIV-2 proteases

Scientific reports, 2018-04, Vol.8 (1), p.5789-15, Article 5789

2018

Volltextzugriff (PDF)

Probing Structural Changes among Analogous Inhibitor-Bound Forms of HIV‑1 Protease and a Drug-Resistant Mutant in Solution by Nuclear Magnetic Resonance

Biochemistry (Easton), 2018-03, Vol.57 (10), p.1652-1662

2018

Volltextzugriff (PDF)

HIV‐1 protease molecular dynamics of a wild‐type and of the V82F/I84V mutant: Possible contributions to drug resistance and a potential new target site for drugs

Protein science, 2004-04, Vol.13 (4), p.1108-1123

2004

Volltextzugriff (PDF)

Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro

Medical science monitor, 2012-08, Vol.18 (8), p.BR293-BR298

2012

Volltextzugriff (PDF)

Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease

Journal of enzyme inhibition and medicinal chemistry, 2019, Vol.34 (1), p.1451-1456

2019

Volltextzugriff (PDF)

TMC310911, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor, Shows In Vitro an Improved Resistance Profile and Higher Genetic Barrier to Resistance Compared with Current Protease Inhibitors

Antimicrobial Agents and Chemotherapy, 2011-12, Vol.55 (12), p.5723-5731

2011

Volltextzugriff (PDF)

Antiviral activity and active components of the leaves from Sabia parviflora Wall. ex Roxb

Natural product research, 2024-06, Vol.38 (12), p.2151-2154

2024

Volltextzugriff (PDF)

Anti-HIV-1 protease activity of compounds from Boesenbergia pandurata

Bioorganic & medicinal chemistry, 2006-03, Vol.14 (6), p.1710-1714

2006

Volltextzugriff (PDF)

Strategies in the rational drug design

Current medicinal chemistry, 2011-06, Vol.18 (17), p.2517-2530

2011

Volltextzugriff (PDF)

Mutation Patterns and Structural Correlates in Human Immunodeficiency Virus Type 1 Protease following Different Protease Inhibitor Treatments

Journal of Virology, 2003-04, Vol.77 (8), p.4836-4847

2003

Volltextzugriff (PDF)

Resilience to resistance of HIV-1 protease inhibitors: profile of darunavir

AIDS reviews, 2008-07, Vol.10 (3), p.131-142

2008

Volltextzugriff (PDF)

Overview of boosted protease inhibitors in treatment-experienced HIV-infected patients

Journal of antimicrobial chemotherapy, 2007-12, Vol.60 (6), p.1195-1205

Youle, Mike

2007

Volltextzugriff (PDF)

Interplay between Single Resistance-Associated Mutations in the HIV-1 Protease and Viral Infectivity, Protease Activity, and Inhibitor Sensitivity

Antimicrobial Agents and Chemotherapy, 2012-02, Vol.56 (2), p.623-633

2012

Volltextzugriff (PDF)

Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance

Journal of medicinal chemistry, 2006-08, Vol.49 (17), p.5252-5261

2006

Volltextzugriff (PDF)

1 – 25 von 7.572

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(6.682)
Mit Volltextzugriff
(5.501)

Publikationsform

1 weiteren anzeigen...

Weniger anzeigen...

Sprache

12 weitere anzeigen...

Weniger anzeigen...

Erscheinungsjahr

n.n

Thema

Humans
(6.841)
Science & Technology
(5.910)
Life Sciences & Biomedicine
(5.539)
Hiv Infections - Drug Therapy
(4.473)
Male
(3.108)
Infectious Diseases
(2.956)
Biological And Medical Sciences
(2.821)
Female
(2.783)
Medical Sciences
(2.692)
Adult
(2.591)
Hiv-1 - Drug Effects
(2.590)
Aids/hiv
(2.584)
Hiv Protease Inhibitors - Therapeutic Use
(2.411)
Human Immunodeficiency Virus
(2.401)
Hiv
(2.326)
Hiv Protease Inhibitors - Adverse Effects
(2.168)
Hiv Protease Inhibitors - Pharmacology
(2.090)
Pharmacology. Drug Treatments
(1.998)
Pharmacology & Pharmacy
(1.742)
Hiv Infections - Virology
(1.736)

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease

Elucidating the druggable interface of protein–protein interactions using fragment docking and coevolutionary analysis

Improving Viral Protease Inhibitors to Counter Drug Resistance

Transition States, Analogues, and Drug Development

Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

A new structural theme in C2-symmetric HIV-1 protease inhibitors : ortho-Substituted P1/P1' side chains

Hydration Structure and Dynamics of Inhibitor-Bound HIV‑1 Protease

Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization

Complex Patterns of Protease Inhibitor Resistance among Antiretroviral Treatment-Experienced HIV-2 Patients from Senegal: Implications for Second-Line Therapy

New anti-HIV agents and targets

Highly Potent HIV‑1 Protease Inhibitors with Novel Tricyclic P2 Ligands: Design, Synthesis, and Protein–Ligand X‑ray Studies

Exploration of the effect of sequence variations located inside the binding pocket of HIV-1 and HIV-2 proteases

Probing Structural Changes among Analogous Inhibitor-Bound Forms of HIV‑1 Protease and a Drug-Resistant Mutant in Solution by Nuclear Magnetic Resonance

HIV‐1 protease molecular dynamics of a wild‐type and of the V82F/I84V mutant: Possible contributions to drug resistance and a potential new target site for drugs

Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro

Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease

TMC310911, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor, Shows In Vitro an Improved Resistance Profile and Higher Genetic Barrier to Resistance Compared with Current Protease Inhibitors

Antiviral activity and active components of the leaves from Sabia parviflora Wall. ex Roxb

Anti-HIV-1 protease activity of compounds from Boesenbergia pandurata

Strategies in the rational drug design

Mutation Patterns and Structural Correlates in Human Immunodeficiency Virus Type 1 Protease following Different Protease Inhibitor Treatments

Resilience to resistance of HIV-1 protease inhibitors: profile of darunavir

Overview of boosted protease inhibitors in treatment-experienced HIV-infected patients

Interplay between Single Resistance-Associated Mutations in the HIV-1 Protease and Viral Infectivity, Protease Activity, and Inhibitor Sensitivity

Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance

Suchergebnisse filtern