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Pro-survival Phenotype of HIF-1α: Neuroprotection Through Inflammatory Mechanisms

Oxygen Transport to Tissue XLIV, 2023, p.33-36

2023

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HIF-1α pathway: role, regulation and intervention for cancer therapy

Acta pharmaceutica Sinica. B, 2015-09, Vol.5 (5), p.378-389

2015

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Advances in inhibition of protein-protein interactions targeting hypoxia-inducible factor-1 for cancer therapy

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1145-1158

2019

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Metabolic dysfunction mediated by HIF-1α contributes to epithelial differentiation defects in eosinophilic esophagitis

Journal of allergy and clinical immunology, 2024-08

2024

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Myeloid PHD2 deficiency accelerates neointima formation via Hif-1α

Molecular immunology, 2022-09, Vol.149, p.48-58

2022

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Role of hypoxia-inducible-factor-1α (HIF-1α) in ferroptosis of adipose tissue during ketosis

Journal of dairy science, 2024-07

2024

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Hypoxic mesenchymal stem cell-derived exosomes alleviate ulcerative colitis injury by limiting intestinal epithelial cells reactive oxygen species accumulation and DNA damage through HIF-1α

International immunopharmacology, 2022-12, Vol.113, p.109426-109426, Article 109426

2022

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Hyperuricemia induces liver injury by upregulating HIF-1α and inhibiting arginine biosynthesis pathway in mouse liver and human L02 hepatocytes

Biochemical and biophysical research communications, 2022-08, Vol.617 (Pt 2), p.55-61

2022

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Patients with obstructive sleep apnea present with chronic upregulation of serum HIF-1α protein

Journal of clinical sleep medicine, 2020-10, Vol.16 (10), p.1761-1768

2020

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Effects of NRF-1 and PGC-1α cooperation on HIF-1α and rat cardiomyocyte apoptosis under hypoxia

Gene, 2022-08, Vol.834, p.146565-146565, Article 146565

2022

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Chronic and Cycling Hypoxia: Drivers of Cancer Chronic Inflammation through HIF-1 and NF-κB Activation: A Review of the Molecular Mechanisms

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10701

2021

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Design, synthesis, molecular dynamics and gene silencing studies of novel therapeutic HIF-1α siRNAs in hypoxic cancer cells

International journal of biological macromolecules, 2024-12, Vol.282 (Pt 3), p.136943, Article 136943

2024

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L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro

Heliyon, 2023-02, Vol.9 (2), p.e13222-e13222, Article e13222

2023

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High expression of HIF-1α alleviates benzene-induced hematopoietic toxicity and immunosuppression in mice

Environmental pollution (1987), 2022-10, Vol.311, p.119928-119928, Article 119928

2022

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HIF-1α is required to differentiate the neonatal Macrophage protein secretome from adults

Cellular immunology, 2024-09, Vol.403-404, p.104861, Article 104861

2024

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A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease

Cell metabolism, 2019-09, Vol.30 (3), p.493-507.e6

2019

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The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy

Expert opinion on drug discovery, 2019-07, Vol.14 (7), p.667-682

2019

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Glioma angiogenesis is boosted by ELK3 activating the HIF-1$$\alpha$$/VEGF-A signaling axis

BMC cancer, 2023-12, Vol.23 (1), Article 662

2023

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HIF-1α enhances autophagy to alleviate apoptosis in marginal cells in the stria vascular in neonatal rats under hypoxia

The international journal of biochemistry & cell biology, 2022-08, Vol.149, p.106259-106259, Article 106259

2022

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Predictive value of serum HIF-1α and VEGF for arrhythmia in acute coronary syndrome patients

Experimental biology and medicine (Maywood, N.J.), 2023-04, Vol.248 (8), p.685-690

2023

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HIF-1α stabilization inhibits Japanese encephalitis virus propagation and neurotoxicity via autophagy pathways

Biochemical and biophysical research communications, 2024-12, Vol.736, p.150853, Article 150853

2024

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TME-responsive nanoplatform for multimodal imaging-guided synergistic precision therapy of esophageal cancer via inhibiting HIF-1α signal pathway

Journal of controlled release, 2024-12, Vol.376, p.518-529

2024

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Unveiling the proteome of the fasting heart: Insights into HIF-1 pathway regulation

Frontiers in physiology, 2024-10, Vol.15, p.1462014

2024

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Influenza A virus-induced glycolysis facilitates virus replication by activating ROS/HIF-1α pathway

Free radical biology & medicine, 2024-11

2024

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HIF-1α protects nucleus pulposus cells from oxidative stress-induced mitochondrial impairment through PDK-1

Free radical biology & medicine, 2024-11, Vol.224, p.39-49

2024

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Pro-survival Phenotype of HIF-1α: Neuroprotection Through Inflammatory Mechanisms

HIF-1α pathway: role, regulation and intervention for cancer therapy

Advances in inhibition of protein-protein interactions targeting hypoxia-inducible factor-1 for cancer therapy

Metabolic dysfunction mediated by HIF-1α contributes to epithelial differentiation defects in eosinophilic esophagitis

Myeloid PHD2 deficiency accelerates neointima formation via Hif-1α

Role of hypoxia-inducible-factor-1α (HIF-1α) in ferroptosis of adipose tissue during ketosis

Hypoxic mesenchymal stem cell-derived exosomes alleviate ulcerative colitis injury by limiting intestinal epithelial cells reactive oxygen species accumulation and DNA damage through HIF-1α

Hyperuricemia induces liver injury by upregulating HIF-1α and inhibiting arginine biosynthesis pathway in mouse liver and human L02 hepatocytes

Patients with obstructive sleep apnea present with chronic upregulation of serum HIF-1α protein

Effects of NRF-1 and PGC-1α cooperation on HIF-1α and rat cardiomyocyte apoptosis under hypoxia

Chronic and Cycling Hypoxia: Drivers of Cancer Chronic Inflammation through HIF-1 and NF-κB Activation: A Review of the Molecular Mechanisms

Design, synthesis, molecular dynamics and gene silencing studies of novel therapeutic HIF-1α siRNAs in hypoxic cancer cells

L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro

High expression of HIF-1α alleviates benzene-induced hematopoietic toxicity and immunosuppression in mice

HIF-1α is required to differentiate the neonatal Macrophage protein secretome from adults

A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease

The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy

Glioma angiogenesis is boosted by ELK3 activating the HIF-1$$\alpha$$/VEGF-A signaling axis

HIF-1α enhances autophagy to alleviate apoptosis in marginal cells in the stria vascular in neonatal rats under hypoxia

Predictive value of serum HIF-1α and VEGF for arrhythmia in acute coronary syndrome patients

HIF-1α stabilization inhibits Japanese encephalitis virus propagation and neurotoxicity via autophagy pathways

TME-responsive nanoplatform for multimodal imaging-guided synergistic precision therapy of esophageal cancer via inhibiting HIF-1α signal pathway

Unveiling the proteome of the fasting heart: Insights into HIF-1 pathway regulation

Influenza A virus-induced glycolysis facilitates virus replication by activating ROS/HIF-1α pathway

HIF-1α protects nucleus pulposus cells from oxidative stress-induced mitochondrial impairment through PDK-1

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