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miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1L

Experimental cell research, 2019-12, Vol.385 (1), p.111597-111597, Article 111597

2019

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DOT1L/H3K79me2 represses HIV-1 reactivation via recruiting DCAF1

Cell reports (Cambridge), 2024-07, Vol.43 (7), p.114368, Article 114368

2024

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The epigenetic enzyme DOT1L orchestrates vascular smooth muscle cell-monocyte crosstalk and protects against atherosclerosis via the NF-κB pathway

European heart journal, 2022-11, Vol.43 (43), p.4562-4576

2022

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Effect of the key histone modifications on the expression of genes related to breast cancer

Genomics (San Diego, Calif.), 2020-01, Vol.112 (1), p.853-858

2020

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The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8⁺ T cells

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (34), p.20706-20716

2020

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DNA damage repair is suppressed in porcine aged oocytes

Journal of animal science and technology, 2021-09, Vol.63 (5), p.984-997

2021

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Integrative analysis reveals functional and regulatory roles of H3K79me2 in mediating alternative splicing

Genome medicine, 2018-04, Vol.10 (1), p.30-30, Article 30

2018

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MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

Cell reports (Cambridge), 2017-01, Vol.18 (2), p.482-495

2017

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Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-β production by mediating H3K79me2/3 methylation in macrophages

Cellular & molecular immunology, 2020-01, Vol.17 (1), p.76-84

2020

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DOT1L affects colorectal carcinogenesis via altering T cell subsets and oncogenic pathway

Oncoimmunology, 2022-12, Vol.11 (1), p.2052640-2052640

2022

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Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer

Molecular oncology, 2019-04, Vol.13 (4), p.873-893

2019

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Recognition of driver genes with potential prognostic implications in lung adenocarcinoma based on H3K79me2

Computational and structural biotechnology journal, 2022, Vol.20, p.5535-5546

2022

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Single-cell transcriptomics defines Dot1L interacting partners and downstream target genes in the mouse molar dental pulp

The International journal of developmental biology, 2022, Vol.66 (7-8-9), p.391

2022

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Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia

eLife, 2021-07, Vol.10

2021

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The risk model construction of the genes regulated by H3K36me3 and H3K79me2 in breast cancer

Biophysics reports, 2023-02, Vol.9 (1), p.45-52

2023

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Mitotic accumulation of dimethylated lysine 79 of histone H3 is important for maintaining genome integrity during mitosis in human cells

Genetics (Austin), 2015-02, Vol.199 (2), p.423-433

2015

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Histone modification mapping in human brain reveals aberrant expression of histone H3 lysine 79 dimethylation in neural tube defects

Neurobiology of disease, 2013-06, Vol.54, p.404-413

2013

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Genomic Marks Associated with Chromatin Compartments in the CTCF, RNAPII Loop and Genomic Windows

International journal of molecular sciences, 2021-10, Vol.22 (21), p.11591

2021

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A lesson learned from the H3.3K27M mutation found in pediatric glioma: A new approach to the study of the function of histone modifications in vivo?

Cell cycle (Georgetown, Tex.), 2013-08, Vol.12 (16), p.2546-2552

2013

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Identification of Key Histone Modifications and Their Regulatory Regions on Gene Expression Level Changes in Chronic Myelogenous Leukemia

Frontiers in cell and developmental biology, 2021-01, Vol.8, p.621578-621578

2021

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Bioinformatic Analyses of Broad H3K79me2 Domains in Different Leukemia Cell Line Data Sets

Cells (Basel, Switzerland), 2022-09, Vol.11 (18), p.2830

2022

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DNA damage repair is suppressed in porcine aged oocytes

한국축산학회지, 2021, 63(5), , pp.984-997

2021

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Histone methyltransferase DOT1L mediates the TGF-β1/Smad3 signaling pathway through epigenetic modification of SYK in myocardial infarction

Human cell : official journal of Human Cell Research Society, 2022, Vol.35 (1), p.98-110

2022

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Antiproliferative and Antimigration Activities of Fluoro-Neplanocin A via Inhibition of Histone H3 Methylation in Triple-Negative Breast Cancer

Biomolecules (Basel, Switzerland), 2020-03, Vol.10 (4), p.530

2020

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Changes in Epigenetic Patterns Related to DNA Replication in Vicia faba Root Meristem Cells under Cadmium-Induced Stress Conditions

Cells (Basel, Switzerland), 2021-12, Vol.10 (12), p.3409

2021

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miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1L

DOT1L/H3K79me2 represses HIV-1 reactivation via recruiting DCAF1

The epigenetic enzyme DOT1L orchestrates vascular smooth muscle cell-monocyte crosstalk and protects against atherosclerosis via the NF-κB pathway

Effect of the key histone modifications on the expression of genes related to breast cancer

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8⁺ T cells

DNA damage repair is suppressed in porcine aged oocytes

Integrative analysis reveals functional and regulatory roles of H3K79me2 in mediating alternative splicing

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-β production by mediating H3K79me2/3 methylation in macrophages

DOT1L affects colorectal carcinogenesis via altering T cell subsets and oncogenic pathway

Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer

Recognition of driver genes with potential prognostic implications in lung adenocarcinoma based on H3K79me2

Single-cell transcriptomics defines Dot1L interacting partners and downstream target genes in the mouse molar dental pulp

Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia

The risk model construction of the genes regulated by H3K36me3 and H3K79me2 in breast cancer

Mitotic accumulation of dimethylated lysine 79 of histone H3 is important for maintaining genome integrity during mitosis in human cells

Histone modification mapping in human brain reveals aberrant expression of histone H3 lysine 79 dimethylation in neural tube defects

Genomic Marks Associated with Chromatin Compartments in the CTCF, RNAPII Loop and Genomic Windows

A lesson learned from the H3.3K27M mutation found in pediatric glioma: A new approach to the study of the function of histone modifications in vivo?

Identification of Key Histone Modifications and Their Regulatory Regions on Gene Expression Level Changes in Chronic Myelogenous Leukemia

Bioinformatic Analyses of Broad H3K79me2 Domains in Different Leukemia Cell Line Data Sets

DNA damage repair is suppressed in porcine aged oocytes

Histone methyltransferase DOT1L mediates the TGF-β1/Smad3 signaling pathway through epigenetic modification of SYK in myocardial infarction

Antiproliferative and Antimigration Activities of Fluoro-Neplanocin A via Inhibition of Histone H3 Methylation in Triple-Negative Breast Cancer

Changes in Epigenetic Patterns Related to DNA Replication in Vicia faba Root Meristem Cells under Cadmium-Induced Stress Conditions

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