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A versatile stereocontrolled synthesis of 2-deoxyiminosugar C-glycosides and their evaluation as glycosidase inhibitors

Organic & biomolecular chemistry, 2021-02, Vol.19 (5), p.1083-1099

2021

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Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo-C-allyl iminosugar

Organic & biomolecular chemistry, 2019, Vol.17 (30), p.7204-7214

2019

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Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review

European journal of medicinal chemistry, 2019-07, Vol.173, p.117-153

2019

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Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion

European journal of medicinal chemistry, 2019-09, Vol.177, p.362-373

2019

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Design, synthesis, characterization, enzymatic inhibition evaluations, and docking study of novel quinazolinone derivatives

International journal of biological macromolecules, 2021-02, Vol.170, p.1-12

2021

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Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potential α-glucosidase inhibitors

European journal of medicinal chemistry, 2017-01, Vol.125, p.423-429

2017

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Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α-glucosidase inhibitory activity, and molecular modeling studies

European journal of medicinal chemistry, 2016-10, Vol.122, p.196-204

2016

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Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors

Bioorganic chemistry, 2019-04, Vol.85, p.191-197

2019

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Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies

European journal of medicinal chemistry, 2015-03, Vol.92, p.387-400

2015

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Structural Modification of Natural Product Ganomycin I Leading to Discovery of a α‑Glucosidase and HMG-CoA Reductase Dual Inhibitor Improving Obesity and Metabolic Dysfunction in Vivo

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3609-3625

2018

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N‑Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α‑Glucosidases I and II with Antiviral Activity

Journal of medicinal chemistry, 2021-12, Vol.64 (24), p.18010-18024

2021

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Recent Advances in Synthetic α‐Glucosidase Inhibitors

ChemMedChem, 2017-06, Vol.12 (11), p.819-829

2017

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Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors

Bioorganic chemistry, 2019-02, Vol.82, p.86-99

2019

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Synthesis of novel flavone hydrazones: In-vitro evaluation of α-glucosidase inhibition, QSAR analysis and docking studies

European journal of medicinal chemistry, 2015-11, Vol.105, p.156-170

2015

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Conformational and Electronic Variations in 1,2‐ and 1,5a‐Cyclophellitols and their Impact on Retaining α‐Glucosidase Inhibition

Chemistry : a European journal, 2024-06, Vol.30 (31), p.e202400723-n/a

2024

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Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α-glucosidase inhibitory activity, and in silico studies

European journal of medicinal chemistry, 2017-09, Vol.138, p.255-272

2017

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Synthesis and molecular docking studies of potent α-glucosidase inhibitors based on biscoumarin skeleton

European journal of medicinal chemistry, 2014-06, Vol.81, p.245-252

2014

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Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

Bioorganic chemistry, 2020-07, Vol.100, p.103897-103897, Article 103897

2020

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A facile approach synthesis of benzoylaryl benzimidazole as potential α-amylase and α-glucosidase inhibitor with antioxidant activity

Bioorganic chemistry, 2021-09, Vol.114, p.105073-105073, Article 105073

2021

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Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives

Bioorganic chemistry, 2018-04, Vol.77, p.586-592

2018

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Synthesis, biological evaluation and molecular docking studies of chromone hydrazone derivatives as α-glucosidase inhibitors

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (13), p.2957-2961

2017

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Synthesis and biological evaluation of some novel 1,2,3-triazole hybrids of myrrhanone B isolated from Commiphora mukul gum resin: Identification of potent antiproliferative leads active against prostate cancer cells (PC-3)

European journal of medicinal chemistry, 2020-02, Vol.188, p.111974-111974, Article 111974

2020

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2-Aryl benzimidazoles: Synthesis, In vitro α-amylase inhibitory activity, and molecular docking study

European journal of medicinal chemistry, 2018-04, Vol.150, p.248-260

2018

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Synthesis, docking and ADMET studies of novel chalcone triazoles for anti-cancer and anti-diabetic activity

European journal of medicinal chemistry, 2015-03, Vol.93, p.564-573

2015

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Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone

Bioorganic chemistry, 2021-09, Vol.114, p.105069-105069, Article 105069

2021

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A versatile stereocontrolled synthesis of 2-deoxyiminosugar C-glycosides and their evaluation as glycosidase inhibitors

Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo-C-allyl iminosugar

Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review

Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion

Design, synthesis, characterization, enzymatic inhibition evaluations, and docking study of novel quinazolinone derivatives

Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potential α-glucosidase inhibitors

Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α-glucosidase inhibitory activity, and molecular modeling studies

Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors

Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies

Structural Modification of Natural Product Ganomycin I Leading to Discovery of a α‑Glucosidase and HMG-CoA Reductase Dual Inhibitor Improving Obesity and Metabolic Dysfunction in Vivo

N‑Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α‑Glucosidases I and II with Antiviral Activity

Recent Advances in Synthetic α‐Glucosidase Inhibitors

Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors

Synthesis of novel flavone hydrazones: In-vitro evaluation of α-glucosidase inhibition, QSAR analysis and docking studies

Conformational and Electronic Variations in 1,2‐ and 1,5a‐Cyclophellitols and their Impact on Retaining α‐Glucosidase Inhibition

Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α-glucosidase inhibitory activity, and in silico studies

Synthesis and molecular docking studies of potent α-glucosidase inhibitors based on biscoumarin skeleton

Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

A facile approach synthesis of benzoylaryl benzimidazole as potential α-amylase and α-glucosidase inhibitor with antioxidant activity

Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives

Synthesis, biological evaluation and molecular docking studies of chromone hydrazone derivatives as α-glucosidase inhibitors

Synthesis and biological evaluation of some novel 1,2,3-triazole hybrids of myrrhanone B isolated from Commiphora mukul gum resin: Identification of potent antiproliferative leads active against prostate cancer cells (PC-3)

2-Aryl benzimidazoles: Synthesis, In vitro α-amylase inhibitory activity, and molecular docking study

Synthesis, docking and ADMET studies of novel chalcone triazoles for anti-cancer and anti-diabetic activity

Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone

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