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GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

Scientific reports, 2022-01, Vol.12 (1), p.1429-1429, Article 1429

2022

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Small‐Molecule Inhibition of Glucose Transporters GLUT‐1–4

Chembiochem : a European journal of chemical biology, 2020-01, Vol.21 (1-2), p.45-52

2020

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Molecular basis of ligand recognition and transport by glucose transporters

Nature (London), 2015-10, Vol.526 (7573), p.391-396

2015

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WZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site

The Journal of biological chemistry, 2016-12, Vol.291 (52), p.26762-26772

2016

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Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

The Journal of biological chemistry, 2016-08, Vol.291 (33), p.17271-17282

2016

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Experimental and Theoretical Data on the Mechanism by Which Red Wine Anthocyanins Are Transported through a Human MKN-28 Gastric Cell Model

Journal of agricultural and food chemistry, 2015-09, Vol.63 (35), p.7685-7692

2015

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The facilitative glucose transporter GLUT3: 20 years of distinction

American journal of physiology: endocrinology and metabolism, 2008-08, Vol.295 (2), p.E242-E253

2008

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Sequence determinants of GLUT1 oligomerization: analysis by homology-scanning mutagenesis

The Journal of biological chemistry, 2013-07, Vol.288 (28), p.20734-20744

2013

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Crystallization and Structural Determination of the Human Glucose Transporters GLUT1 and GLUT3

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1713, p.15

2018

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The border between the ultrabithorax and abdominal-A regulatory domains in the Drosophila bithorax complex

Genetics (Austin), 2013-04, Vol.193 (4), p.1135-1147

2013

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The intrinsic structure of glucose transporter isoforms Glut1 and Glut3 regulates their differential distribution to detergent‐resistant membrane domains in nonpolarized mammalian cells

The FEBS journal, 2007-06, Vol.274 (11), p.2843-2853

2007

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The protein family of glucose transport facilitators: It's not only about glucose after all

IUBMB life, 2010-05, Vol.62 (5), p.315-333

Augustin, Robert

2010

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A Novel Fluorescence Resonance Energy Transfer-Based Screen in High-Throughput Format To Identify Inhibitors of Malarial and Human Glucose Transporters

Antimicrobial agents and chemotherapy, 2016-12, Vol.60 (12), p.7407-7414

2016

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Comparison of the expression and spatial localization of glucose transporters in the rat, bovine and human lens

Experimental eye research, 2017-08, Vol.161, p.193-204

2017

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Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3

Angewandte Chemie (International ed.), 2019-11, Vol.58 (47), p.17016-17025

International ed. in English, 2019

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The role of glucose transporters in the distribution of p-aminophenyl-α-d-mannopyranoside modified liposomes within mice brain

Journal of controlled release, 2014-05, Vol.182, p.99-110

2014

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Activation of brain glucose metabolism ameliorating cognitive impairment in APP/PS1 transgenic mice by electroacupuncture

Free radical biology & medicine, 2017-11, Vol.112, p.174-190

2017

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Transcript levels of class I GLUTs within individual tissues and the direct relationship between GLUT1 expression and glucose metabolism in Atlantic cod (Gadus morhua)

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2014-05, Vol.184 (4), p.483-496

2014

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A high fat diet potentiates neonatal iron overload-induced memory impairments in rats

European journal of nutrition, 2024-06, Vol.63 (4), p.1163-1175

2024

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Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile

The international journal of biochemistry & cell biology, 2012-11, Vol.44 (11), p.2077-2084

2012

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Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models

Food & function, 2018-11, Vol.9 (11), p.5682-5696

2018

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RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53

Cellular and molecular life sciences : CMLS, 2022-05, Vol.79 (5), p.270-270, Article 270

2022

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Synaptic activity‐induced glycolysis facilitates membrane lipid provision and neurite outgrowth

The EMBO journal, 2018-05, Vol.37 (9), p.n/a

2018

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Anti-Diabetic Effect of a Shihunine-Rich Extract of Dendrobium loddigesii on 3T3-L1 Cells and db/db Mice by Up-Regulating AMPK-GLUT4-PPARα

Molecules (Basel, Switzerland), 2019-07, Vol.24 (14), p.2673

2019

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Molecular Interaction of Anti‐Diabetic Drugs With Acetylcholinesterase and Sodium Glucose Co‐Transporter 2

Journal of cellular biochemistry, 2017-11, Vol.118 (11), p.3855-3865

Shakil, Shazi

2017

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GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

Small‐Molecule Inhibition of Glucose Transporters GLUT‐1–4

Molecular basis of ligand recognition and transport by glucose transporters

WZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site

Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

Experimental and Theoretical Data on the Mechanism by Which Red Wine Anthocyanins Are Transported through a Human MKN-28 Gastric Cell Model

The facilitative glucose transporter GLUT3: 20 years of distinction

Sequence determinants of GLUT1 oligomerization: analysis by homology-scanning mutagenesis

Crystallization and Structural Determination of the Human Glucose Transporters GLUT1 and GLUT3

The border between the ultrabithorax and abdominal-A regulatory domains in the Drosophila bithorax complex

The intrinsic structure of glucose transporter isoforms Glut1 and Glut3 regulates their differential distribution to detergent‐resistant membrane domains in nonpolarized mammalian cells

The protein family of glucose transport facilitators: It's not only about glucose after all

A Novel Fluorescence Resonance Energy Transfer-Based Screen in High-Throughput Format To Identify Inhibitors of Malarial and Human Glucose Transporters

Comparison of the expression and spatial localization of glucose transporters in the rat, bovine and human lens

Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3

The role of glucose transporters in the distribution of p-aminophenyl-α-d-mannopyranoside modified liposomes within mice brain

Activation of brain glucose metabolism ameliorating cognitive impairment in APP/PS1 transgenic mice by electroacupuncture

Transcript levels of class I GLUTs within individual tissues and the direct relationship between GLUT1 expression and glucose metabolism in Atlantic cod (Gadus morhua)

A high fat diet potentiates neonatal iron overload-induced memory impairments in rats

Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile

Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models

RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53

Synaptic activity‐induced glycolysis facilitates membrane lipid provision and neurite outgrowth

Anti-Diabetic Effect of a Shihunine-Rich Extract of Dendrobium loddigesii on 3T3-L1 Cells and db/db Mice by Up-Regulating AMPK-GLUT4-PPARα

Molecular Interaction of Anti‐Diabetic Drugs With Acetylcholinesterase and Sodium Glucose Co‐Transporter 2

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