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Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging

Biochimica et biophysica acta. General subjects, 2017-10, Vol.1861 (10), p.2494-2506

2017

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Syntheses of Fluorescent Gangliosides for the Studies of Raft Domains

Methods in enzymology, 2017, Vol.597, p.239-263

2017

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Intranasal infusion of GD3 and GM1 gangliosides downregulates alpha-synuclein and controls tyrosine hydroxylase gene in a PD model mouse

Molecular therapy, 2021-10, Vol.29 (10), p.3059-3071

2021

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Revealing the Raft Domain Organization in the Plasma Membrane by Single-Molecule Imaging of Fluorescent Ganglioside Analogs

Methods in enzymology, 2018, Vol.598, p.267-282

2018

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Amylin and pramlintide modulate γ-secretase level and APP processing in lipid rafts

Scientific reports, 2020-02, Vol.10 (1), p.3751-3751, Article 3751

2020

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Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal

International journal of antimicrobial agents, 2020-08, Vol.56 (2), p.106020-106020, Article 106020

2020

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Subnormal GM1 in PBMCs: Promise for Early Diagnosis of Parkinson's Disease?

International journal of molecular sciences, 2021-10, Vol.22 (21), p.11522

2021

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Regulation of signal transduction by gangliosides in lipid rafts: focus on GM3–IR and GM1–TrkA interactions

FEBS letters, 2022-12, Vol.596 (24), p.3124-3132

2022

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The glycolipid GM1 reshapes asymmetric biomembranes and giant vesicles by curvature generation

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (22), p.5756-5761

2018

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HIV-1 incorporation of host-cell–derived glycosphingolipid GM3 allows for capture by mature dendritic cells

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (19), p.7475-7480

2012

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Binding Cooperativity Matters: A GM1-Like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array

PloS one, 2016-04, Vol.11 (4), p.e0153265-e0153265

2016

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Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis

Cell metabolism, 2020-08, Vol.32 (2), p.188-202.e5

2020

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The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis

Nature medicine, 2011-01, Vol.17 (1), p.105-109

2011

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Acceleration of α-Synuclein Aggregation by Exosomes

The Journal of biological chemistry, 2015-01, Vol.290 (5), p.2969-2982

2015

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Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans

Journal of neuroscience research, 2012-10, Vol.90 (10), p.1997-2008

2012

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Mice deficient in GM1 manifest both motor and non-motor symptoms of Parkinson's disease; successful treatment with synthetic GM1 ganglioside

Experimental neurology, 2020-07, Vol.329, p.113284-113284, Article 113284

2020

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GM1 Ganglioside: Past Studies and Future Potential

Molecular neurobiology, 2016-04, Vol.53 (3), p.1824-1842

2016

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Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway

PloS one, 2023-02, Vol.18 (2), p.e0281414-e0281414

2023

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Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage

Human molecular genetics, 2008-06, Vol.17 (11), p.1556-1568

2008

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Turning the spotlight on the oligosaccharide chain of GM1 ganglioside

Glycoconjugate journal, 2021-02, Vol.38 (1), p.101-117

2021

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Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 synthase deficiency variants

Human molecular genetics, 2023-12, Vol.32 (24), p.3323-3341

2023

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Role of the GM1 ganglioside oligosaccharide portion in the TrkA‐dependent neurite sprouting in neuroblastoma cells

Journal of neurochemistry, 2017-12, Vol.143 (6), p.645-659

2017

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GM1-Modified Lipoprotein-like Nanoparticle: Multifunctional Nanoplatform for the Combination Therapy of Alzheimer’s Disease

ACS nano, 2015-11, Vol.9 (11), p.10801-10816

2015

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Enhanced Susceptibility to Kainate-Induced Seizures, Neuronal Apoptosis, and Death in Mice Lacking Gangliotetraose Gangliosides: Protection with LIGA 20, a Membrane-Permeant Analog of GM1

The Journal of neuroscience, 2005-11, Vol.25 (47), p.11014-11022

2005

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Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging

Syntheses of Fluorescent Gangliosides for the Studies of Raft Domains

Intranasal infusion of GD3 and GM1 gangliosides downregulates alpha-synuclein and controls tyrosine hydroxylase gene in a PD model mouse

Revealing the Raft Domain Organization in the Plasma Membrane by Single-Molecule Imaging of Fluorescent Ganglioside Analogs

Amylin and pramlintide modulate γ-secretase level and APP processing in lipid rafts

Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal

Subnormal GM1 in PBMCs: Promise for Early Diagnosis of Parkinson's Disease?

Regulation of signal transduction by gangliosides in lipid rafts: focus on GM3–IR and GM1–TrkA interactions

The glycolipid GM1 reshapes asymmetric biomembranes and giant vesicles by curvature generation

HIV-1 incorporation of host-cell–derived glycosphingolipid GM3 allows for capture by mature dendritic cells

Binding Cooperativity Matters: A GM1-Like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array

Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis

The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis

Acceleration of α-Synuclein Aggregation by Exosomes

Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans

Mice deficient in GM1 manifest both motor and non-motor symptoms of Parkinson's disease; successful treatment with synthetic GM1 ganglioside

GM1 Ganglioside: Past Studies and Future Potential

Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity

Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway

Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage

Turning the spotlight on the oligosaccharide chain of GM1 ganglioside

Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 synthase deficiency variants

Role of the GM1 ganglioside oligosaccharide portion in the TrkA‐dependent neurite sprouting in neuroblastoma cells

GM1-Modified Lipoprotein-like Nanoparticle: Multifunctional Nanoplatform for the Combination Therapy of Alzheimer’s Disease

Enhanced Susceptibility to Kainate-Induced Seizures, Neuronal Apoptosis, and Death in Mice Lacking Gangliotetraose Gangliosides: Protection with LIGA 20, a Membrane-Permeant Analog of GM1

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