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Targeted delivery of α-galactosylceramide to CD8α+ dendritic cells optimizes type I NKT cell-based antitumor responses

The Journal of immunology (1950), 2014-07, Vol.193 (2), p.961-969

2014

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Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (19), p.7142-7143

2012

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Liposomal α‐galactosylceramide is taken up by gut‐associated lymphoid tissue and stimulates local and systemic immune responses

Journal of pharmacy and pharmacology, 2017-12, Vol.69 (12), p.1724-1735

2017

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Glucosylceramide and galactosylceramide, small glycosphingolipids with significant impact on health and disease

Glycobiology (Oxford), 2021-12, Vol.31 (11), p.1416-1434

2021

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α‐galactosylceramide generates lung regulatory T cells through the activated natural killer T cells in mice

Journal of cellular and molecular medicine, 2019-02, Vol.23 (2), p.1072-1085

2019

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Synthesis and Evaluation of Liposomal Anti-GM3 Cancer Vaccine Candidates Covalently and Noncovalently Adjuvanted by αGalCer

Journal of medicinal chemistry, 2021-02, Vol.64 (4), p.1951-1965

2021

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α-Galactosylceramide and peptide-based nano-vaccine synergistically induced a strong tumor suppressive effect in melanoma

Acta biomaterialia, 2018-08, Vol.76, p.193-207

2018

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Natural Killer T Cells Are Involved in Atherosclerotic Plaque Instability in Apolipoprotein-E Knockout Mice

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12451

2021

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α‐Galactosylceramide‐activated murine NK1.1+ invariant‐NKT cells in the myometrium induce miscarriages in mice

European journal of immunology, 2016-08, Vol.46 (8), p.1867-1877

2016

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Innate Vα14⁺ natural killer T cells mature dendritic cells, leading to strong adaptive immunity

Immunological reviews, 2007-12, Vol.220 (1), p.183-198

2007

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A phase I vaccination study with dendritic cells loaded with NY-ESO-1 and α-galactosylceramide: induction of polyfunctional T cells in high-risk melanoma patients

Cancer Immunology, Immunotherapy, 2018-02, Vol.67 (2), p.285-298

2018

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The Adjuvant of α-Galactosylceramide Presented by Gold Nanoparticles Enhances Antitumor Immune Responses of MUC1 Antigen-Based Tumor Vaccines

International journal of nanomedicine, 2021, Vol.16, p.403-420

2021

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THE REGULATORY ROLE OF Vα14 NKT CELLS IN INNATE AND ACQUIRED IMMUNE RESPONSE

Annual review of immunology, 2003-04, Vol.21 (1), p.483-513

2003

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Two bacterial glycosphingolipid synthases responsible for the synthesis of glucuronosylceramide and α-galactosylceramide

The Journal of biological chemistry, 2020-07, Vol.295 (31), p.10709-10725

2020

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Self-Adjuvanting Lipoprotein Conjugate αGalCer-RBD Induces Potent Immunity against SARS-CoV‑2 and its Variants of Concern

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.2558-2570

2022

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Miscarriage induced by adoptive transfer of dendritic cells and invariant natural killer T cells into mice

European journal of immunology, 2018-06, Vol.48 (6), p.937-949

2018

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Fully Synthetic Invariant NKT Cell-Dependent Self-Adjuvanting Antitumor Vaccines Eliciting Potent Immune Response in Mice

Molecular pharmaceutics, 2020-02, Vol.17 (2), p.417-425, Article acs.molpharmaceut.9b00720

2020

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Front Cover: Chemical Biology of αGalCer: A Chemist's Toolbox for the Stimulation of Invariant Natural Killer T (iNKT) Cells (Eur. J. Org. Chem. 26/2022)

European journal of organic chemistry, 2022-07, Vol.2022 (26), p.n/a

2022

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Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection

Clinical immunology (Orlando, Fla.), 2011-08, Vol.140 (2), p.130-141

2011

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GALC Expression in Macrophages Improves Peripheral Krabbe Disease

Trends in Glycoscience and Glycotechnology, 2020/11/25, Vol.32(190), pp.J189-J189

Watanabe, Takashi

2020

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Invariant NKT cell-augmented GM-CSF-secreting tumor vaccine is effective in advanced prostate cancer model

Cancer Immunology, Immunotherapy, 2022-12, Vol.71 (12), p.2943-2955

2022

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Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity

Cell chemical biology, 2018-05, Vol.25 (5), p.571-584.e8

2018

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Non‐glycosidic compounds can stimulate both human and mouse iNKT cells

European journal of immunology, 2016-05, Vol.46 (5), p.1224-1234

2016

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Unaltered influenza disease outcomes in swine prophylactically treated with α-galactosylceramide

Developmental and comparative immunology, 2021-01, Vol.114, p.103843-103843, Article 103843

2021

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Participation of galactosylceramide and sulfatide in glycosynapses between oligodendrocyte or myelin membranes

FEBS letters, 2010-05, Vol.584 (9), p.1771-1778

2010

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Targeted delivery of α-galactosylceramide to CD8α+ dendritic cells optimizes type I NKT cell-based antitumor responses

Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice

Liposomal α‐galactosylceramide is taken up by gut‐associated lymphoid tissue and stimulates local and systemic immune responses

Glucosylceramide and galactosylceramide, small glycosphingolipids with significant impact on health and disease

α‐galactosylceramide generates lung regulatory T cells through the activated natural killer T cells in mice

Synthesis and Evaluation of Liposomal Anti-GM3 Cancer Vaccine Candidates Covalently and Noncovalently Adjuvanted by αGalCer

α-Galactosylceramide and peptide-based nano-vaccine synergistically induced a strong tumor suppressive effect in melanoma

Natural Killer T Cells Are Involved in Atherosclerotic Plaque Instability in Apolipoprotein-E Knockout Mice

α‐Galactosylceramide‐activated murine NK1.1+ invariant‐NKT cells in the myometrium induce miscarriages in mice

Innate Vα14⁺ natural killer T cells mature dendritic cells, leading to strong adaptive immunity

A phase I vaccination study with dendritic cells loaded with NY-ESO-1 and α-galactosylceramide: induction of polyfunctional T cells in high-risk melanoma patients

The Adjuvant of α-Galactosylceramide Presented by Gold Nanoparticles Enhances Antitumor Immune Responses of MUC1 Antigen-Based Tumor Vaccines

THE REGULATORY ROLE OF Vα14 NKT CELLS IN INNATE AND ACQUIRED IMMUNE RESPONSE

Two bacterial glycosphingolipid synthases responsible for the synthesis of glucuronosylceramide and α-galactosylceramide

Self-Adjuvanting Lipoprotein Conjugate αGalCer-RBD Induces Potent Immunity against SARS-CoV‑2 and its Variants of Concern

Miscarriage induced by adoptive transfer of dendritic cells and invariant natural killer T cells into mice

Fully Synthetic Invariant NKT Cell-Dependent Self-Adjuvanting Antitumor Vaccines Eliciting Potent Immune Response in Mice

Front Cover: Chemical Biology of αGalCer: A Chemist's Toolbox for the Stimulation of Invariant Natural Killer T (iNKT) Cells (Eur. J. Org. Chem. 26/2022)

Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection

GALC Expression in Macrophages Improves Peripheral Krabbe Disease

Invariant NKT cell-augmented GM-CSF-secreting tumor vaccine is effective in advanced prostate cancer model

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity

Non‐glycosidic compounds can stimulate both human and mouse iNKT cells

Unaltered influenza disease outcomes in swine prophylactically treated with α-galactosylceramide

Participation of galactosylceramide and sulfatide in glycosynapses between oligodendrocyte or myelin membranes

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