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Ketamine alleviates PTSD-like effect and improves hippocampal synaptic plasticity via regulation of GSK-3β/GR signaling of rats

Journal of psychiatric research, 2024-10, Vol.178, p.259-269

2024

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GSK-3β in DNA repair, apoptosis, and resistance of chemotherapy, radiotherapy of cancer

Biochimica et biophysica acta. Molecular cell research, 2020-05, Vol.1867 (5), p.118659-118659, Article 118659

2020

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Intracellular effects of lithium in aging neurons

Ageing research reviews, 2024-08, Vol.99, p.102396, Article 102396

2024

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Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis

Biochemical pharmacology, 2021-10, Vol.192, p.114676-114676, Article 114676

2021

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Curcumin induces mitochondrial apoptosis in human hepatoma cells through BCLAF1-mediated modulation of PI3K/AKT/GSK-3β signaling

Life sciences (1973), 2022-10, Vol.306, p.120804-120804, Article 120804

2022

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Glycogen synthase kinase-3 beta inhibitors as novel cancer treatments and modulators of antitumor immune responses

Cancer biology & therapy, 2019-08, Vol.20 (8), p.1047-1056

2019

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Neuroprotective effect of Apelin 13 on ischemic stroke by activating AMPK/GSK-3β/Nrf2 signaling

Journal of neuroinflammation, 2019-02, Vol.16 (1), p.24-24, Article 24

2019

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BACE1 inhibitors: Current status and future directions in treating Alzheimer's disease

Medicinal research reviews, 2020-01, Vol.40 (1), p.339-384

2020

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Dexmedetomidine attenuates lipopolysaccharide-induced liver oxidative stress and cell apoptosis in rats by increasing GSK-3β/MKP-1/Nrf2 pathway activity via the α2 adrenergic receptor

Toxicology and applied pharmacology, 2019-02, Vol.364, p.144-152

2019

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Early synaptic deficits in GSK-3β overexpressing mice

Neuroscience letters, 2022-07, Vol.784, p.136744-136744, Article 136744

2022

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Selenium alleviates heart remodeling through Sirt1/AKT/GSK-3β pathway

International immunopharmacology, 2022-10, Vol.111, p.109158-109158, Article 109158

2022

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Gastrodin ameliorates synaptic impairment, mitochondrial dysfunction and oxidative stress in N2a/APP cells

Biochemical and biophysical research communications, 2024-07, Vol.719, p.150127-150127, Article 150127

2024

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TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways

Cell, 2022-10, Vol.185 (22), p.4153-4169.e19

2022

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Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2022-11, Vol.242, p.114689-114689, Article 114689

2022

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Sevoflurane suppresses NLRP3 inflammasome-mediated pyroptotic cell death to attenuate lipopolysaccharide-induced acute lung injury through inducing GSK-3β phosphorylation and activation

International immunopharmacology, 2022-08, Vol.109, p.108800-108800, Article 108800

2022

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Icariin, a natural flavonoid glucoside, inhibits neuroinflammation in mice with triple-transgenic Alzheimer’s disease by regulating the Akt/GSK-3β signaling pathway

Journal of functional foods, 2024-07, Vol.118, p.106263, Article 106263

2024

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Novel insights into gut health: Cilostazol strengthens gut integrity by adjusting TLR-2/NF-κB/IL-23 and CD44/AKT/GSK-3β/cyclin-D1 trajectories in methotrexate-induced mucositis model

European journal of pharmacology, 2024-07, Vol.975, p.176669-176669, Article 176669

2024

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Chondrocytes-derived exosomal miR-8485 regulated the Wnt/β-catenin pathways to promote chondrogenic differentiation of BMSCs

Biochemical and biophysical research communications, 2020-03, Vol.523 (2), p.506-513

2020

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Natural compound screening predicts novel GSK-3 isoform-specific inhibitors

Biochimie, 2024-10, Vol.225, p.68-80

2024

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Ginsenoside Rh4 Alleviates Amyloid β Plaque and Tau Hyperphosphorylation by Regulating Neuroinflammation and the Glycogen Synthase Kinase 3β Signaling Pathway

Journal of agricultural and food chemistry, 2023-09, Vol.71 (37), p.13783-13794

2023

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Multi-strain probiotics ameliorate Alzheimer’s-like cognitive impairment and pathological changes through the AKT/GSK-3β pathway in senescence-accelerated mouse prone 8 mice

Brain, behavior, and immunity, 2024-07, Vol.119, p.14-27

2024

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Structure-activity relationship (SAR) studies of synthetic glycogen synthase kinase-3β inhibitors: A critical review

European journal of medicinal chemistry, 2019-02, Vol.164, p.448-470

2019

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Deletion of Glycogen Synthase Kinase-3β in D2 Receptor–Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor–Dependent Synaptic Plasticity

Biological psychiatry (1969), 2020-04, Vol.87 (8), p.745-755

2020

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Fisetin alleviates thioacetamide-induced hepatic fibrosis in rats by inhibiting Wnt/β-catenin signaling pathway

Immunopharmacology and immunotoxicology, 2022-06, Vol.44 (3), p.355-366

2022

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Overexpression of lemur tyrosine kinase-2 protects neurons from oxygen-glucose deprivation/reoxygenation-induced injury through reinforcement of Nrf2 signaling by modulating GSK-3β phosphorylation

Biochemical and biophysical research communications, 2020-01, Vol.521 (4), p.964-970

2020

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Ketamine alleviates PTSD-like effect and improves hippocampal synaptic plasticity via regulation of GSK-3β/GR signaling of rats

GSK-3β in DNA repair, apoptosis, and resistance of chemotherapy, radiotherapy of cancer

Intracellular effects of lithium in aging neurons

Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis

Curcumin induces mitochondrial apoptosis in human hepatoma cells through BCLAF1-mediated modulation of PI3K/AKT/GSK-3β signaling

Glycogen synthase kinase-3 beta inhibitors as novel cancer treatments and modulators of antitumor immune responses

Neuroprotective effect of Apelin 13 on ischemic stroke by activating AMPK/GSK-3β/Nrf2 signaling

BACE1 inhibitors: Current status and future directions in treating Alzheimer's disease

Dexmedetomidine attenuates lipopolysaccharide-induced liver oxidative stress and cell apoptosis in rats by increasing GSK-3β/MKP-1/Nrf2 pathway activity via the α2 adrenergic receptor

Early synaptic deficits in GSK-3β overexpressing mice

Selenium alleviates heart remodeling through Sirt1/AKT/GSK-3β pathway

Gastrodin ameliorates synaptic impairment, mitochondrial dysfunction and oxidative stress in N2a/APP cells

TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease

Sevoflurane suppresses NLRP3 inflammasome-mediated pyroptotic cell death to attenuate lipopolysaccharide-induced acute lung injury through inducing GSK-3β phosphorylation and activation

Icariin, a natural flavonoid glucoside, inhibits neuroinflammation in mice with triple-transgenic Alzheimer’s disease by regulating the Akt/GSK-3β signaling pathway

Novel insights into gut health: Cilostazol strengthens gut integrity by adjusting TLR-2/NF-κB/IL-23 and CD44/AKT/GSK-3β/cyclin-D1 trajectories in methotrexate-induced mucositis model

Chondrocytes-derived exosomal miR-8485 regulated the Wnt/β-catenin pathways to promote chondrogenic differentiation of BMSCs

Natural compound screening predicts novel GSK-3 isoform-specific inhibitors

Ginsenoside Rh4 Alleviates Amyloid β Plaque and Tau Hyperphosphorylation by Regulating Neuroinflammation and the Glycogen Synthase Kinase 3β Signaling Pathway

Multi-strain probiotics ameliorate Alzheimer’s-like cognitive impairment and pathological changes through the AKT/GSK-3β pathway in senescence-accelerated mouse prone 8 mice

Structure-activity relationship (SAR) studies of synthetic glycogen synthase kinase-3β inhibitors: A critical review

Deletion of Glycogen Synthase Kinase-3β in D2 Receptor–Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor–Dependent Synaptic Plasticity

Fisetin alleviates thioacetamide-induced hepatic fibrosis in rats by inhibiting Wnt/β-catenin signaling pathway

Overexpression of lemur tyrosine kinase-2 protects neurons from oxygen-glucose deprivation/reoxygenation-induced injury through reinforcement of Nrf2 signaling by modulating GSK-3β phosphorylation

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