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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

Scientific reports, 2018-05, Vol.8 (1), p.7228-20, Article 7228

2018

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lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

Molecular therapy, 2022-02, Vol.30 (2), p.688-702

2022

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Polarized focal adhesion kinase activity within a focal adhesion during cell migration

Nature chemical biology, 2023-12, Vol.19 (12), p.1458-1468

2023

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FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis

The FASEB journal, 2018-02, Vol.32 (2), p.1099-1107

2018

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Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules

Nutrients, 2017-09, Vol.9 (10), p.1073

2017

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Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer

Journal of experimental & clinical cancer research, 2018-07, Vol.37 (1), p.175-175, Article 175

2018

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Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

The Journal of cell biology, 2007-02, Vol.176 (5), p.667-680

2007

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FAK dimerization controls its kinase-dependent functions at focal adhesions

The EMBO journal, 2014-02, Vol.33 (4), p.356-370

2014

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Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition

The Journal of cell biology, 2016-02, Vol.212 (3), p.349-364

2016

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YAP regulates cell mechanics by controlling focal adhesion assembly

Nature communications, 2017-05, Vol.8 (1), p.15321-15321, Article 15321

2017

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Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells

The Journal of cell biology, 2018-01, Vol.217 (1), p.375-395

2018

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ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis through PI3K/Akt Signaling and MAPK-Dependent Focal Adhesion Disassembly

Cancer research (Chicago, Ill.), 2021-02, Vol.81 (4), p.986-1000

2021

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Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2508-2520

2019

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A post-invasion role for Chlamydia type III effector TarP in modulating the dynamics and organization of host cell focal adhesions

The Journal of biological chemistry, 2020-10, Vol.295 (43), p.14763-14779

2020

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Distinct focal adhesion protein modules control different aspects of mechanotransduction

Journal of cell science, 2017-05, Vol.130 (9), p.1612-1624

2017

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Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes

PloS one, 2014-03, Vol.9 (3), p.e92059

2014

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CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling

Nature cell biology, 2021-07, Vol.23 (7), p.758

2021

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ECT2 promotes lung adenocarcinoma progression through extracellular matrix dynamics and focal adhesion signaling

Cancer science, 2021-02, Vol.112 (2), p.703-714

2021

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Cardiac Differentiation Promotes Focal Adhesions Assembly through Vinculin Recruitment

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2444

2023

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Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

Nature communications, 2021-04, Vol.12 (1), p.2359-2359, Article 2359

2021

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Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling

Molecular pharmacology, 2016-05, Vol.89 (5), p.521-540

2016

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Focal adhesions: a personal perspective on a half century of progress

The FEBS journal, 2017-10, Vol.284 (20), p.3355-3361

Burridge, Keith

2017

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The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions

Cancer discovery, 2012-08, Vol.2 (8), p.706-721

2012

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Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

Journal of cell science, 2011-04, Vol.124 (Pt 8), p.1195-1205

2011

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Control of cellular responses to mechanical cues through YAP/TAZ regulation

The Journal of biological chemistry, 2019-11, Vol.294 (46), p.17693-17706

2019

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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

Polarized focal adhesion kinase activity within a focal adhesion during cell migration

FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis

Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules

Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

FAK dimerization controls its kinase-dependent functions at focal adhesions

Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition

YAP regulates cell mechanics by controlling focal adhesion assembly

Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells

ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis through PI3K/Akt Signaling and MAPK-Dependent Focal Adhesion Disassembly

Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions

A post-invasion role for Chlamydia type III effector TarP in modulating the dynamics and organization of host cell focal adhesions

Distinct focal adhesion protein modules control different aspects of mechanotransduction

Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes

CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling

ECT2 promotes lung adenocarcinoma progression through extracellular matrix dynamics and focal adhesion signaling

Cardiac Differentiation Promotes Focal Adhesions Assembly through Vinculin Recruitment

Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling

Focal adhesions: a personal perspective on a half century of progress

The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

Control of cellular responses to mechanical cues through YAP/TAZ regulation

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