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Polarized focal adhesion kinase activity within a focal adhesion during cell migration

Nature chemical biology, 2023-12, Vol.19 (12), p.1458

2023

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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

Scientific reports, 2018-05, Vol.8 (1), p.7228-20, Article 7228

2018

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FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis

The FASEB journal, 2018-02, Vol.32 (2), p.1099-1107

2018

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Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition

The Journal of cell biology, 2016-02, Vol.212 (3), p.349-364

2016

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Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2508-2520

2019

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Distinct focal adhesion protein modules control different aspects of mechanotransduction

Journal of cell science, 2017-05, Vol.130 (9), p.1612-1624

2017

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Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes

PloS one, 2014-03, Vol.9 (3), p.e92059

2014

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Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

Nature communications, 2021-04, Vol.12 (1), p.2359-2359, Article 2359

2021

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Phosphorylated paxillin and phosphorylated FAK constitute subregions within focal adhesions

Journal of cell science, 2022-04, Vol.135 (7)

2022

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Synergistic phase separation of two pathways promotes integrin clustering and nascent adhesion formation

eLife, 2022-01, Vol.11

2022

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Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling

Molecular pharmacology, 2016-05, Vol.89 (5), p.521-540

2016

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Effect of Focal Adhesion Kinase and Vinculin Expression on Migration Parameters of Normal and Tumor Epitheliocytes

Biochemistry (Moscow), 2024-03, Vol.89 (3), p.474-486

2024

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Understanding the Roles of FAK in Cancer: Inhibitors, Genetic Models, and New Insights

Journal of Histochemistry & Cytochemistry, 2015-02, Vol.63 (2), p.114-128

2015

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PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

The Journal of cell biology, 2008-01, Vol.180 (1), p.187-203

2008

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Immobilization after injury alters extracellular matrix and stem cell fate

The Journal of clinical investigation, 2020-10, Vol.130 (10), p.5444-5460

2020

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Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity

Cell, 2015-09, Vol.163 (1), p.160-173

2015

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Targeting FAK in human cancer: from finding to first clinical trials

Frontiers in bioscience (Landmark. Print), 2014-01, Vol.19 (4), p.687-706

Golubovskaya, Vita M

2014

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FAK signaling in cancer-associated fibroblasts promotes breast cancer cell migration and metastasis by exosomal miRNAs-mediated intercellular communication

Oncogene, 2020-03, Vol.39 (12), p.2539-2549

2020

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Identification of a novel type of focal adhesion remodelling via FAK/FRNK replacement, and its contribution to cancer progression

Cell death & disease, 2023-04, Vol.14 (4), p.256-256, Article 256

2023

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lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

Molecular therapy, 2022-02, Vol.30 (2), p.688-702

2022

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Molecular and functional insight into focal adhesion kinases: Therapeutic implications for oral malignancies

Drug discovery today, 2024-01, Vol.29 (1), p.103852-103852, Article 103852

2024

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Focal adhesion regulation of cell behavior

BBA - Molecular Cell Research, 2004-07, Vol.1692 (2), p.103-119

2004

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Focal adhesion dynamics in cellular function and disease

Cellular signalling, 2021-09, Vol.85, p.110046-110046, Article 110046

2021

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Dynamic regulation of KIF15 phosphorylation and acetylation promotes focal adhesions disassembly in pancreatic cancer

Cell death & disease, 2022-10, Vol.13 (10), p.896-896, Article 896

2022

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A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction

Nature communications, 2020-07, Vol.11 (1), p.3282-3282, Article 3282

2020

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