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Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

Journal of lipid research, 2017-02, Vol.58 (2), p.412-419

2017

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Rapid Postnatal Upregulation of Intestinal Farnesoid X Receptor‐Fibroblast Growth Factor 19 Signaling in Premature Pigs

Journal of pediatric gastroenterology and nutrition, 2020-05, Vol.70 (5), p.e94-e99

2020

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Geniposidic acid protected against ANIT-induced hepatotoxity and acute intrahepatic cholestasis, due to Fxr-mediated regulation of Bsep and Mrp2

Journal of ethnopharmacology, 2016-02, Vol.179, p.197-207

2016

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Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis

Journal of lipid research, 2017-03, Vol.58 (3), p.519-528

2017

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Bile Acids and the Gut Microbiome as Potential Targets for NAFLD Treatment

Journal of pediatric gastroenterology and nutrition, 2018-07, Vol.67 (1), p.3-5

2018

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Agonist of farnesoid X receptor protects against bile acid induced damage and oxidative stress in mouse placenta – A study on maternal cholestasis model

Placenta (Eastbourne), 2015-05, Vol.36 (5), p.545-551

2015

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Mechanistic evaluation of AMPK/SIRT1/FXR signaling axis, inflammation, and redox status in thioacetamide‐induced liver cirrhosis: The role of Cichorium intybus linn (chicory)‐supplemented diet

Journal of food biochemistry, 2019-08, Vol.43 (8), p.e12938-n/a

2019

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Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists

Bioorganic & medicinal chemistry, 2012-06, Vol.20 (11), p.3429-3445

2012

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Ursodeoxycholic acid suppresses eosinophilic airway inflammation by inhibiting the function of dendritic cells through the nuclear farnesoid X receptor

Allergy (Copenhagen), 2012-12, Vol.67 (12), p.1501-1510

2012

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Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis[S]

Journal of lipid research, 2011-08, Vol.52 (8), p.1561-1568

2011

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A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis

Journal of hepatology, 2020-07, Vol.73 (1), p.94-101

2020

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Enterobacteria-mediated deconjugation of taurocholic acid enhances ileal farnesoid X receptor signaling

European journal of pharmacology, 2012-12, Vol.697 (1-3), p.132-138

2012

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On the relationship of anthranilic derivatives structure and the FXR (Farnesoid X receptor) agonist activity

Journal of biomolecular structure & dynamics, 2018-12, Vol.36 (16), p.4378-4391

2018

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Bile acids and cardiovascular function in cirrhosis

Liver international, 2017-10, Vol.37 (10), p.1420-1430

2017

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Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discovery

Bioorganic & medicinal chemistry, 2013-07, Vol.21 (14), p.4266-4278

2013

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Inhibition of farnesoid X receptor controls esophageal cancer cell growth in vitro and in nude mouse xenografts

Cancer, 2013-04, Vol.119 (7), p.1321-1329

2013

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Bile Acids Activated Receptors Regulate Innate Immunity

Frontiers in immunology, 2018-08, Vol.9, p.1853-1853

2018

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The gut-liver axis in liver disease: Pathophysiological basis for therapy

Journal of hepatology, 2020-03, Vol.72 (3), p.558-577

2020

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Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis

Cell metabolism, 2023-10, Vol.35 (10), p.1752-1766.e8

2023

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Long-Term Obeticholic Acid Therapy Improves Histological Endpoints in Patients With Primary Biliary Cholangitis

Clinical gastroenterology and hepatology, 2020-05, Vol.18 (5), p.1170-1178.e6

2020

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Current and emerging pharmacological options for the treatment of nonalcoholic steatohepatitis

Metabolism, clinical and experimental, 2020-10, Vol.111, p.154203-154203, Article 154203

2020

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Experimental and computational analysis of 1-(4-chloro-3-nitrophenyl)-3-(3,4-dichlorophenyl)thiourea

Journal of molecular structure, 2020-04, Vol.1205, p.127587, Article 127587

2020

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FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption

Cell metabolism, 2021-08, Vol.33 (8), p.1671-1684.e4

2021

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Nuclear Receptor Interdomain Communication is Mediated by the Hinge with Ligand Specificity

Journal of molecular biology, 2024-09, Vol.436 (22), p.168805, Article 168805

2024

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Saffron offers hepatoprotection via up-regulation of hepatic farnesoid-X-activated receptors in a rat model of acetaminophen-induced hepatotoxicity

Avicenna journal of phytomedicine, 2021-11, Vol.11 (6), p.622-632

2021

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Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

Rapid Postnatal Upregulation of Intestinal Farnesoid X Receptor‐Fibroblast Growth Factor 19 Signaling in Premature Pigs

Geniposidic acid protected against ANIT-induced hepatotoxity and acute intrahepatic cholestasis, due to Fxr-mediated regulation of Bsep and Mrp2

Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis

Bile Acids and the Gut Microbiome as Potential Targets for NAFLD Treatment

Agonist of farnesoid X receptor protects against bile acid induced damage and oxidative stress in mouse placenta – A study on maternal cholestasis model

Mechanistic evaluation of AMPK/SIRT1/FXR signaling axis, inflammation, and redox status in thioacetamide‐induced liver cirrhosis: The role of Cichorium intybus linn (chicory)‐supplemented diet

Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists

Ursodeoxycholic acid suppresses eosinophilic airway inflammation by inhibiting the function of dendritic cells through the nuclear farnesoid X receptor

Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis[S]

A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis

Enterobacteria-mediated deconjugation of taurocholic acid enhances ileal farnesoid X receptor signaling

On the relationship of anthranilic derivatives structure and the FXR (Farnesoid X receptor) agonist activity

Bile acids and cardiovascular function in cirrhosis

Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discovery

Inhibition of farnesoid X receptor controls esophageal cancer cell growth in vitro and in nude mouse xenografts

Bile Acids Activated Receptors Regulate Innate Immunity

The gut-liver axis in liver disease: Pathophysiological basis for therapy

Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis

Long-Term Obeticholic Acid Therapy Improves Histological Endpoints in Patients With Primary Biliary Cholangitis

Current and emerging pharmacological options for the treatment of nonalcoholic steatohepatitis

Experimental and computational analysis of 1-(4-chloro-3-nitrophenyl)-3-(3,4-dichlorophenyl)thiourea

FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption

Nuclear Receptor Interdomain Communication is Mediated by the Hinge with Ligand Specificity

Saffron offers hepatoprotection via up-regulation of hepatic farnesoid-X-activated receptors in a rat model of acetaminophen-induced hepatotoxicity

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