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A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus

The Journal of immunology (1950), 2010-12, Vol.185 (12), p.7413-7425

2010

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Immunogenicity of Immunotoxins Containing Pseudomonas Exotoxin A: Causes, Consequences, and Mitigation

Frontiers in immunology, 2020-06, Vol.11, p.1261

2020

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Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study

Clinical and vaccine immunology, 2016-12, Vol.23 (12), p.908-917

2016

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Staphylococcal and Streptococcal Superantigen Exotoxins

Clinical Microbiology Reviews, 2013-07, Vol.26 (3), p.422-447

2013

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A guide to taming a toxin – recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer

The FEBS journal, 2011-12, Vol.278 (23), p.4683-4700

2011

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Immunogenicity of therapeutic recombinant immunotoxins

Immunological reviews, 2016-03, Vol.270 (1), p.152-164

2016

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Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis

Nature communications, 2015-03, Vol.6 (1), p.6536-6536, Article 6536

2015

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Depletion of regulatory T cells in tumors with an anti-CD25 immunotoxin induces CD8 T cell-mediated systemic antitumor immunity

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (10), p.4575-4582

2019

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Removing T-cell epitopes with computational protein design

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (23), p.8577-8582

2014

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Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia

Blood, 2017-10, Vol.130 (14), p.1620-1627

2017

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Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (23), p.8571-8576

2014

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Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (8)

2022

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C. elegans Detects Pathogen-Induced Translational Inhibition to Activate Immune Signaling

Cell host & microbe, 2012-04, Vol.11 (4), p.375-386

2012

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Host Translational Inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an Immune Response in Caenorhabditis elegans

Cell host & microbe, 2012-04, Vol.11 (4), p.364-374

2012

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Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotox

Clinical cancer research, 2011-10, Vol.17 (20), p.6398-6405

2011

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Assessment of the impact of manufacturing changes on the physicochemical properties of the recombinant vaccine carrier ExoProtein A

Vaccine, 2019-09, Vol.37 (38), p.5762-5769

2019

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Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome

Journal of leukocyte biology, 2012-11, Vol.92 (5), p.1069-1081

2012

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Human single-chain antibodies that neutralize Pseudomonas aeruginosa-exotoxin A-mediated cellular apoptosis

Scientific reports, 2019-10, Vol.9 (1), p.14928-15, Article 14928

2019

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Deimmunizing substitutions in Pseudomonas exotoxin domain III perturb antigen processing without eliminating T-cell epitopes

The Journal of biological chemistry, 2019-03, Vol.294 (12), p.4667-4681

2019

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Streptococcal superantigen‐induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death and reduced immunoglobulin release

Clinical and experimental immunology, 2019-07, Vol.197 (1), p.83-94

2019

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Cysteine proteinase SpeB from Streptococcus pyogenes - a potent modifier of immunologically important host and bacterial proteins

Biological chemistry, 2011-12, Vol.392 (12), p.1077--

2011

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immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (32), p.11311-11316

2008

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New Life for Immunotoxin Cancer Therapy

Clinical cancer research, 2016-03, Vol.22 (5), p.1055-1058

2016

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Anti-tumor activity of an immunotoxin (TGFα-PE38) delivered by attenuated Salmonella typhimurium

Oncotarget, 2017-06, Vol.8 (23), p.37550-37560

2017

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Streptococcal pyrogenic exotoxin B is a superantigen that induces murine splenocyte proliferation and secretion of IL-2 and IFN-γ ex vivo

FEMS microbiology letters, 2024-01, Vol.371

2024

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A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus

Immunogenicity of Immunotoxins Containing Pseudomonas Exotoxin A: Causes, Consequences, and Mitigation

Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study

Staphylococcal and Streptococcal Superantigen Exotoxins

A guide to taming a toxin – recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer

Immunogenicity of therapeutic recombinant immunotoxins

Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis

Depletion of regulatory T cells in tumors with an anti-CD25 immunotoxin induces CD8 T cell-mediated systemic antitumor immunity

Removing T-cell epitopes with computational protein design

Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia

Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes

Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production

C. elegans Detects Pathogen-Induced Translational Inhibition to Activate Immune Signaling

Host Translational Inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an Immune Response in Caenorhabditis elegans

Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotox

Assessment of the impact of manufacturing changes on the physicochemical properties of the recombinant vaccine carrier ExoProtein A

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome

Human single-chain antibodies that neutralize Pseudomonas aeruginosa-exotoxin A-mediated cellular apoptosis

Deimmunizing substitutions in Pseudomonas exotoxin domain III perturb antigen processing without eliminating T-cell epitopes

Streptococcal superantigen‐induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death and reduced immunoglobulin release

Cysteine proteinase SpeB from Streptococcus pyogenes - a potent modifier of immunologically important host and bacterial proteins

immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes

New Life for Immunotoxin Cancer Therapy

Anti-tumor activity of an immunotoxin (TGFα-PE38) delivered by attenuated Salmonella typhimurium

Streptococcal pyrogenic exotoxin B is a superantigen that induces murine splenocyte proliferation and secretion of IL-2 and IFN-γ ex vivo

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