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Mechanics and Single-Molecule Interrogation of DNA Recombination

Annual review of biochemistry, 2016-06, Vol.85 (1), p.193-226

2016

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A flexible RecC surface loop required for Chi hotspot control of RecBCD enzyme

Genetics (Austin), 2023-03, Vol.223 (3)

2023

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DNA Polymerase Sequences of New World Monkey Cytomegaloviruses: Another Molecular Marker with Which To Infer Platyrrhini Systematics

Journal of virology, 2018-09, Vol.92 (18), p.e00980-18

2018

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Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

eLife, 2022-12, Vol.11

2022

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Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex

The EMBO journal, 2012-03, Vol.31 (6), p.1568-1578

2012

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G-quadruplexes and helicases

Nucleic acids research, 2016-03, Vol.44 (5), p.1989-2006

2016

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Replication fork reversal after replication-transcription collision

PLoS genetics, 2012-04, Vol.8 (4), p.e1002622-e1002622

2012

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ER-directed TREX1 limits cGAS activation at micronuclei

Molecular cell, 2021-02, Vol.81 (4), p.724-738.e9

2021

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Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation

Cell stem cell, 2017-09, Vol.21 (3), p.319-331.e8

2017

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Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

Molecular cell, 2017-09, Vol.67 (5), p.867-881.e7

2017

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Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (42), p.E5699-E5705

2015

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cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing

Molecular cell, 2021-02, Vol.81 (4), p.739-755.e7

2021

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Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome

The Journal of immunology (1950), 2015-09, Vol.195 (5), p.1939-1943

2015

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DNA2 drives processing and restart of reversed replication forks in human cells

The Journal of cell biology, 2015-03, Vol.208 (5), p.545-562

2015

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DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

Molecular cell, 2014-01, Vol.53 (1), p.7-18

2014

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BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

Genes & development, 2011-02, Vol.25 (4), p.350-362

2011

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Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon

Nucleic acids research, 2007-05, Vol.35 (9), p.3076

2007

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ExoCET: exonuclease in vitro assembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes

Nucleic acids research, 2018-03, Vol.46 (5), p.e28-e28

2018

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Phylogenetic Ubiquity and Shuffling of the Bacterial RecBCD and AddAB Recombination Complexes

Journal of Bacteriology, 2009-08, Vol.191 (16), p.5076-5084

CROMIE, Gareth A

2009

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Mechanisms generating cancer genome complexity from a single cell division error

Science (American Association for the Advancement of Science), 2020-04, Vol.368 (6488)

2020

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Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair

Molecular cell, 2017-09, Vol.67 (5), p.891-898.e4

2017

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Double-Strand Break End Resection and Repair Pathway Choice

Annual review of genetics, 2011-01, Vol.45 (1), p.247-271

2011

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TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner

The Journal of immunology (1950), 2014-06, Vol.192 (12), p.5993-5997

2014

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Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

Nature (London), 2011-11, Vol.479 (7372), p.241-244

2011

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Intrinsic self-DNA triggers inflammatory disease dependent on STING

The Journal of immunology (1950), 2014-11, Vol.193 (9), p.4634-4642

2014

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Mechanics and Single-Molecule Interrogation of DNA Recombination

A flexible RecC surface loop required for Chi hotspot control of RecBCD enzyme

DNA Polymerase Sequences of New World Monkey Cytomegaloviruses: Another Molecular Marker with Which To Infer Platyrrhini Systematics

Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex

G-quadruplexes and helicases

Replication fork reversal after replication-transcription collision

ER-directed TREX1 limits cGAS activation at micronuclei

Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation

Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing

Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome

DNA2 drives processing and restart of reversed replication forks in human cells

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon

ExoCET: exonuclease in vitro assembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes

Phylogenetic Ubiquity and Shuffling of the Bacterial RecBCD and AddAB Recombination Complexes

Mechanisms generating cancer genome complexity from a single cell division error

Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair

Double-Strand Break End Resection and Repair Pathway Choice

TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

Intrinsic self-DNA triggers inflammatory disease dependent on STING

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