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Echinocandin Resistance in Candida

Clinical infectious diseases, 2015-12, Vol.61 (suppl_6), p.S612-S617

Perlin, David S.

2015

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Safety and Pharmacokinetics of CD101 IV, a Novel Echinocandin, in Healthy Adults

Antimicrobial agents and chemotherapy, 2017-02, Vol.61 (2)

2017

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Echinocandins: production and applications

Applied microbiology and biotechnology, 2013-04, Vol.97 (8), p.3267-3284

2013

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Echinocandin Antifungal Drugs in Fungal Infections: A Comparison

Drugs (New York, N.Y.), 2011, Vol.71 (1), p.11-41

2011

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Disseminated Candidiasis Caused by Candida albicans with Amino Acid Substitutions in Fks1 at Position Ser645 Cannot Be Successfully Treated with Micafungin

Antimicrobial Agents and Chemotherapy, 2011-07, Vol.55 (7), p.3075-3083

2011

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Unnatural tetradeoxy echinocandins produced by gene cluster design and heterologous expression

Organic & biomolecular chemistry, 2023-05, Vol.21 (17), p.3552-3556

2023

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Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin

Antimicrobial agents and chemotherapy, 2016-11, Vol.60 (11), p.6872-6879

2016

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Structure-Activity Relationships of a Series of Echinocandins and the Discovery of CD101, a Highly Stable and Soluble Echinocandin with Distinctive Pharmacokinetic Properties

Antimicrobial agents and chemotherapy, 2017-02, Vol.61 (2)

2017

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Echinocandins: The Expanding Antifungal Armamentarium

Clinical infectious diseases, 2015-12, Vol.61 (suppl_6), p.S604-S611

2015

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Pharmacodynamic Optimization for Treatment of Invasive Candida auris Infection

Antimicrobial agents and chemotherapy, 2017-08, Vol.61 (8)

2017

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Reshaping Echinocandin Antifungal Drugs To Circumvent Glucan Synthase Point‐Mutation‐Mediated Resistance

Angewandte Chemie International Edition, 2024-02, Vol.63 (9), p.e202314728-n/a

International ed. in English, 2024

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Unraveling Drug Penetration of Echinocandin Antifungals at the Site of Infection in an Intra-abdominal Abscess Model

Antimicrobial agents and chemotherapy, 2017-10, Vol.61 (10)

2017

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Whole genome analysis of echinocandin non-susceptible Candida Glabrata clinical isolates: a multi-center study in China

BMC microbiology, 2023-11, Vol.23 (1), p.341-10, Article 341

2023

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Management of invasive candidiasis: A focus on rezafungin, ibrexafungerp, and fosmanogepix

Pharmacotherapy, 2024-06, Vol.44 (6), p.467-479

2024

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Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters

Antimicrobial agents and chemotherapy, 2017-11, Vol.61 (11)

2017

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Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008

PloS one, 2014-07, Vol.9 (7), p.e101510-e101510

2014

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Biosynthesis of pneumocandin lipopeptides and perspectives for its production and related echinocandins

Applied microbiology and biotechnology, 2018-12, Vol.102 (23), p.9881-9891

2018

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An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment

mBio, 2022-04, Vol.13 (2), p.e0293321-e0293321

2022

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High-Dose Micafungin for Preterm Neonates and Infants with Invasive and Central Nervous System Candidiasis

Antimicrobial agents and chemotherapy, 2016-12, Vol.60 (12), p.7333-7339

2016

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Echinocandin B biosynthesis: a biosynthetic cluster from Aspergillus nidulans NRRL 8112 and reassembly of the subclusters Ecd and Hty from Aspergillus pachycristatus NRRL 11440 reveals a single coherent gene cluster

BMC genomics, 2016-08, Vol.17 (1), p.570-570, Article 570

2016

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Echinocandins - structure, mechanism of action and use in antifungal therapy

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.876-894

2022

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Echinocandin resistance: an emerging clinical problem?

Current opinion in infectious diseases, 2014-12, Vol.27 (6), p.484-492

2014

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Low Caspofungin Exposure in Patients in Intensive Care Units

Antimicrobial agents and chemotherapy, 2017-02, Vol.61 (2)

2017

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Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations

Clinical infectious diseases, 2013-06, Vol.56 (12), p.1724-1732

2013

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Pharmacokinetics of caspofungin in ICU patients

Journal of antimicrobial chemotherapy, 2014-12, Vol.69 (12), p.3294-3299

2014

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Echinocandin Resistance in Candida

Safety and Pharmacokinetics of CD101 IV, a Novel Echinocandin, in Healthy Adults

Echinocandins: production and applications

Echinocandin Antifungal Drugs in Fungal Infections: A Comparison

Disseminated Candidiasis Caused by Candida albicans with Amino Acid Substitutions in Fks1 at Position Ser645 Cannot Be Successfully Treated with Micafungin

Unnatural tetradeoxy echinocandins produced by gene cluster design and heterologous expression

Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin

Structure-Activity Relationships of a Series of Echinocandins and the Discovery of CD101, a Highly Stable and Soluble Echinocandin with Distinctive Pharmacokinetic Properties

Echinocandins: The Expanding Antifungal Armamentarium

Pharmacodynamic Optimization for Treatment of Invasive Candida auris Infection

Reshaping Echinocandin Antifungal Drugs To Circumvent Glucan Synthase Point‐Mutation‐Mediated Resistance

Unraveling Drug Penetration of Echinocandin Antifungals at the Site of Infection in an Intra-abdominal Abscess Model

Whole genome analysis of echinocandin non-susceptible Candida Glabrata clinical isolates: a multi-center study in China

Management of invasive candidiasis: A focus on rezafungin, ibrexafungerp, and fosmanogepix

Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters

Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008

Biosynthesis of pneumocandin lipopeptides and perspectives for its production and related echinocandins

An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment

High-Dose Micafungin for Preterm Neonates and Infants with Invasive and Central Nervous System Candidiasis

Echinocandin B biosynthesis: a biosynthetic cluster from Aspergillus nidulans NRRL 8112 and reassembly of the subclusters Ecd and Hty from Aspergillus pachycristatus NRRL 11440 reveals a single coherent gene cluster

Echinocandins - structure, mechanism of action and use in antifungal therapy

Echinocandin resistance: an emerging clinical problem?

Low Caspofungin Exposure in Patients in Intensive Care Units

Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations

Pharmacokinetics of caspofungin in ICU patients

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