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Targeting EZH2 as cancer therapy

Journal of biochemistry (Tokyo), 2021-07, Vol.170 (1), p.1-4

2021

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LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII

Oncotarget, 2017-07, Vol.8 (29), p.47565-47573

2017

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Treating human cancer by targeting EZH2

Genes & diseases, 2024-04, p.101313, Article 101313

2024

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EZH2 inhibitors sensitize myeloma cell lines to panobinostat resulting in unique combinatorial transcriptomic changes

Oncotarget, 2018-04, Vol.9 (31), p.21930-21942

2018

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EZH2-mediated development of therapeutic resistance in cancer

Cancer letters, 2024-04, Vol.586, p.216706-216706, Article 216706

2024

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USP7 inhibits TIMP2 by up-regulating the expression of EZH2 to activate the NF-κB/PD-L1 axis to promote the development of cervical cancer

Cellular signalling, 2022-08, Vol.96, p.110351-110351, Article 110351

2022

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Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage

Cell death and differentiation, 2011-11, Vol.18 (11), p.1771-1779

2011

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AML-137: Expression of Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Gene (EZH2) In Acute Myeloid Leukemia

Clinical lymphoma, myeloma and leukemia, 2021-09, Vol.21, p.S282-S283

2021

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AML-192: Enhancer of Zeste Homolog 2 (EZH2) in COVID-19-Positive Acute Myeloid Leukemia

Clinical lymphoma, myeloma and leukemia, 2021-09, Vol.21, p.S289-S290

2021

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EZH2 Promotes Glioma Cell Proliferation, Invasion, and Migration via Mir-142-3p/KCNQ1OT1/HMGB3 Axis : Running Title: EZH2 Promotes Glioma cell Malignant Behaviors

Molecular neurobiology, 2024-04

2024

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EZH2: a novel target for cancer treatment

Journal of hematology and oncology, 2020-07, Vol.13 (1), p.104-12, Article 104

2020

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The EZH2 inhibitor GSK343 suppresses cancer stem-like phenotypes and reverses mesenchymal transition in glioma cells

Oncotarget, 2017-11, Vol.8 (58), p.98348-98359

2017

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Cross-species analyses unravel the complexity of H3K27me3 and H4K20me3 in the context of neural stem progenitor cells

Neuroepigenetics, 2016-06, Vol.6, p.10-25

2016

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Novel insights of EZH2-mediated epigenetic modifications in degenerative musculoskeletal diseases

Ageing research reviews, 2023-09, Vol.90, p.102034-102034, Article 102034

2023

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Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis

Oncotarget, 2015-11, Vol.6 (35), p.37335-37348

2015

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The novel EZH2 inhibitor, GSK126, suppresses cell migration and angiogenesis via down-regulating VEGF-A

Cancer chemotherapy and pharmacology, 2016-04, Vol.77 (4), p.757-765

2016

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The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

Oncotarget, 2018-03, Vol.9 (21), p.15512-15525

2018

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Commentary: Serum EZH2 is a novel biomarker for bladder cancer diagnosis and prognosis

Frontiers in oncology, 2024-09, Vol.14

2024

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Resectable Non-Small Cell Lung Cancer Heterogeneity and Recurrence Assessed by Tissue Next-Generation Sequencing Genotyping and Circulating Tumor Cell EZH2 Characterization

Archivos de bronconeumología, 2024-10

2024

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Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression

Cell death and differentiation, 2009-11, Vol.17 (5), p.801-810

2009

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lncRNA HOTAIR Promotes DNA Repair and Radioresistance of Breast Cancer via EZH2

DNA and cell biology, 2020-12, Vol.39 (12), p.2166-2173

2020

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The role of deubiquitinase USP2 in driving bladder cancer progression by stabilizing EZH2 to epigenetically silence SOX1 expression

Translational oncology, 2024-11, Vol.49, p.102104, Article 102104

2024

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Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors

Cell, 2018-09, Vol.175 (1), p.186-199.e19

2018

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SAL protects endothelial cells from H2O2-induced endothelial dysfunction: Regulation of inflammation and autophagy by EZH2

International immunopharmacology, 2024-12, Vol.142 (Pt B), p.113060, Article 113060

2024

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Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition

Phytomedicine (Stuttgart), 2024-09, p.156103, Article 156103

2024

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Targeting EZH2 as cancer therapy

LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII

Treating human cancer by targeting EZH2

EZH2 inhibitors sensitize myeloma cell lines to panobinostat resulting in unique combinatorial transcriptomic changes

EZH2-mediated development of therapeutic resistance in cancer

USP7 inhibits TIMP2 by up-regulating the expression of EZH2 to activate the NF-κB/PD-L1 axis to promote the development of cervical cancer

Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage

AML-137: Expression of Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Gene (EZH2) In Acute Myeloid Leukemia

AML-192: Enhancer of Zeste Homolog 2 (EZH2) in COVID-19-Positive Acute Myeloid Leukemia

EZH2 Promotes Glioma Cell Proliferation, Invasion, and Migration via Mir-142-3p/KCNQ1OT1/HMGB3 Axis : Running Title: EZH2 Promotes Glioma cell Malignant Behaviors

EZH2: a novel target for cancer treatment

The EZH2 inhibitor GSK343 suppresses cancer stem-like phenotypes and reverses mesenchymal transition in glioma cells

Cross-species analyses unravel the complexity of H3K27me3 and H4K20me3 in the context of neural stem progenitor cells

Novel insights of EZH2-mediated epigenetic modifications in degenerative musculoskeletal diseases

Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis

The novel EZH2 inhibitor, GSK126, suppresses cell migration and angiogenesis via down-regulating VEGF-A

The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

Commentary: Serum EZH2 is a novel biomarker for bladder cancer diagnosis and prognosis

Resectable Non-Small Cell Lung Cancer Heterogeneity and Recurrence Assessed by Tissue Next-Generation Sequencing Genotyping and Circulating Tumor Cell EZH2 Characterization

Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression

lncRNA HOTAIR Promotes DNA Repair and Radioresistance of Breast Cancer via EZH2

The role of deubiquitinase USP2 in driving bladder cancer progression by stabilizing EZH2 to epigenetically silence SOX1 expression

Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors

SAL protects endothelial cells from H2O2-induced endothelial dysfunction: Regulation of inflammation and autophagy by EZH2

Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition

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