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Structure of dynein-dynactin on microtubules shows tandem adaptor binding

Nature (London), 2022-10, Vol.610 (7930), p.212-216

2022

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Cryo-EM shows how dynactin recruits two dyneins for faster movement

Nature (London), 2018-02, Vol.554 (7691), p.202-206

2018

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Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated

Cell, 2017-06, Vol.169 (7), p.1303-1314.e18

2017

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Cargo adaptors regulate stepping and force generation of mammalian dynein-dynactin

Nature chemical biology, 2019-11, Vol.15 (11), p.1093-1101

2019

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Molecular mechanism of dynein-dynactin complex assembly by LIS1

Science (American Association for the Advancement of Science), 2024-03, Vol.383 (6690), p.eadk8544-eadk8544

2024

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CryoEM shows the active dynein complex on microtubules

Trends in biochemical sciences (Amsterdam. Regular ed.), 2023-04, Vol.48 (4), p.315-316

2023

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Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

Nature structural & molecular biology, 2018-03, Vol.25 (3), p.203-207

2018

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Dynactin p150 promotes processive motility of DDB complexes by minimizing diffusional behavior of dynein

Molecular biology of the cell, 2020-04, Vol.31 (8), p.782-792

2020

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Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170

Proceedings of the National Academy of Sciences - PNAS, 2021-10, Vol.118 (43)

2021

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How dynein and dynactin transport cargos: a structural perspective

Current opinion in structural biology, 2016-04, Vol.37, p.62-70

2016

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Ndel1 disfavors dynein–dynactin–adaptor complex formation in two distinct ways

The Journal of biological chemistry, 2023-06, Vol.299 (6), p.104735-104735, Article 104735

2023

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The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein

The Journal of cell biology, 2023-05, Vol.222 (5), p.1

2023

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NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation

Nature communications, 2021-12, Vol.12 (1), p.7157-7157, Article 7157

2021

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Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

The Journal of biological chemistry, 2016-08, Vol.291 (35), p.18239-18251

2016

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Cryo‐EM reveals the complex architecture of dynactin's shoulder region and pointed end

The EMBO journal, 2021-04, Vol.40 (8), p.e106164-n/a

2021

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p25 of the dynactin complex plays a dual role in cargo binding and dynactin regulation

The Journal of biological chemistry, 2018-10, Vol.293 (40), p.15606-15619

2018

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On and off controls within dynein-dynactin on native cargoes

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (23)

2021

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Swedish Alzheimer’s disease variant perturbs activity of retrograde molecular motors and causes widespread derangement of axonal transport pathways

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107137-107137, Article 107137

2024

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Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (36), p.E5318-E5327

2016

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Role of BicDR in bristle shaft construction and support of BicD functions

Journal of cell science, 2024-01, Vol.137 (2)

2024

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Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (43), p.E9153-E9162

2017

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Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains

Neurobiology of aging, 2021-11, Vol.107, p.21-29

2021

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Detection of known and novel ALK fusion transcripts in lung cancer patients using next-generation sequencing approaches

Scientific reports, 2017-10, Vol.7 (1), p.12510-11, Article 12510

2017

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DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation

International journal of molecular sciences, 2021-04, Vol.22 (8), p.3985

2021

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Local synthesis of dynein cofactors matches retrograde transport to acutely changing demands

Nature communications, 2016-12, Vol.7 (1), p.13865-13865, Article 13865

2016

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Structure of dynein-dynactin on microtubules shows tandem adaptor binding

Cryo-EM shows how dynactin recruits two dyneins for faster movement

Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated

Cargo adaptors regulate stepping and force generation of mammalian dynein-dynactin

Molecular mechanism of dynein-dynactin complex assembly by LIS1

CryoEM shows the active dynein complex on microtubules

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

Dynactin p150 promotes processive motility of DDB complexes by minimizing diffusional behavior of dynein

Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170

How dynein and dynactin transport cargos: a structural perspective

Ndel1 disfavors dynein–dynactin–adaptor complex formation in two distinct ways

The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein

NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation

Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

Cryo‐EM reveals the complex architecture of dynactin's shoulder region and pointed end

p25 of the dynactin complex plays a dual role in cargo binding and dynactin regulation

On and off controls within dynein-dynactin on native cargoes

Swedish Alzheimer’s disease variant perturbs activity of retrograde molecular motors and causes widespread derangement of axonal transport pathways

Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon

Role of BicDR in bristle shaft construction and support of BicD functions

Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo

Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains

Detection of known and novel ALK fusion transcripts in lung cancer patients using next-generation sequencing approaches

DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation

Local synthesis of dynein cofactors matches retrograde transport to acutely changing demands

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