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Dual-specificity phosphatases: critical regulators with diverse cellular targets

Biochemical journal, 2009-03, Vol.418 (3), p.475-489

2009

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Comparative analysis of dual specificity protein phosphatase genes 1, 2 and 5 in response to immune challenges in Japanese flounder Paralichthys olivaceus

Fish & shellfish immunology, 2017-09, Vol.68, p.368-376

2017

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DUSP26 induces aortic valve calcification by antagonizing MDM2-mediated ubiquitination of DPP4 in human valvular interstitial cells

European heart journal, 2021-08, Vol.42 (30), p.2935-2951

2021

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Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling

The FEBS journal, 2013-01, Vol.280 (2), p.489-504

2013

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Dual-specificity phosphatases: therapeutic targets in cancer therapy resistance

Journal of cancer research and clinical oncology, 2022, Vol.148 (1), p.57-70

2022

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Gene expression profile of mitogen-activated kinases and microRNAs controlling their expression in HaCaT cell culture treated with lipopolysaccharide A and cyclosporine A

Cell cycle (Georgetown, Tex.), 2024-02, Vol.23 (3), p.279-293

2024

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DUSP5 and DUSP6, two ERK specific phosphatases, are markers of a higher MAPK signaling activation in BRAF mutated thyroid cancers

PloS one, 2017-09, Vol.12 (9), p.e0184861

2017

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Mice lacking DUSP6/8 have enhanced ERK1/2 activity and resistance to diet-induced obesity

Biochemical and biophysical research communications, 2020-11, Vol.533 (1), p.17-22

2020

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Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer

Cancer research (Chicago, Ill.), 2013-10, Vol.73 (20), p.6346-6358

2013

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DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells

Molecular cell, 2012-01, Vol.45 (1), p.123-131

2012

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Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases

Chemical reviews, 2018-02, Vol.118 (3), p.1069-1091

2018

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The family-wide structure and function of human dual-specificity protein phosphatases

Acta crystallographica. Section D, Biological crystallography., 2014-02, Vol.70 (2), p.421-435

2014

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Overexpression of dual-specificity phosphatases 4 and 13 attenuates transforming growth factor β1-induced migration and drug resistance in A549 cells in vitro

Biochemical and biophysical research communications, 2022-05, Vol.606, p.35-41

2022

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Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance

Nature medicine, 2012-07, Vol.18 (7), p.1052-1059

2012

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Dual-specificity phosphatases 13 and 27 as key switches in muscle stem cell transition from proliferation to differentiation

Stem cells (Dayton, Ohio), 2024-09, Vol.42 (9), p.830-847

2024

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Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (3), p.E317-E326

2017

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Inhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer

Nature communications, 2024-07, Vol.15 (1), p.5851-19, Article 5851

2024

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Exosomal miR-1228-5p down-regulates DUSP22 to promotes cell proliferation and migration in small cell lung cancer

Life sciences (1973), 2024-08, Vol.351, p.122787, Article 122787

2024

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The phosphatase PAC1 acts as a T cell suppressor and attenuates host antitumor immunity

Nature immunology, 2020-03, Vol.21 (3), p.287-297

2020

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Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1

The Journal of immunology (1950), 2012-03, Vol.188 (5), p.2127-2135

2012

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Upregulation of DUSP6 impairs infectious bronchitis virus replication by negatively regulating ERK pathway and promoting apoptosis

Veterinary research (Paris), 2021-01, Vol.52 (1), p.7-7, Article 7

2021

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Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis

American journal of physiology. Lung cellular and molecular physiology, 2019-11, Vol.317 (5), p.L678-L689

2019

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Cdc14 Phosphatases Preferentially Dephosphorylate a Subset of Cyclin-dependent kinase (Cdk) Sites Containing Phosphoserine

The Journal of biological chemistry, 2012-01, Vol.287 (3), p.1662-1669

2012

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MiR‐21‐5p/dual‐specificity phosphatase 8 signalling mediates the anti‐inflammatory effect of haem oxygenase‐1 in aged intracerebral haemorrhage rats

Aging cell, 2019-12, Vol.18 (6), p.e13022-n/a

2019

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Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (10), p.4583-4591

2019

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Dual-specificity phosphatases: critical regulators with diverse cellular targets

Comparative analysis of dual specificity protein phosphatase genes 1, 2 and 5 in response to immune challenges in Japanese flounder Paralichthys olivaceus

DUSP26 induces aortic valve calcification by antagonizing MDM2-mediated ubiquitination of DPP4 in human valvular interstitial cells

Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling

Dual-specificity phosphatases: therapeutic targets in cancer therapy resistance

Gene expression profile of mitogen-activated kinases and microRNAs controlling their expression in HaCaT cell culture treated with lipopolysaccharide A and cyclosporine A

DUSP5 and DUSP6, two ERK specific phosphatases, are markers of a higher MAPK signaling activation in BRAF mutated thyroid cancers

Mice lacking DUSP6/8 have enhanced ERK1/2 activity and resistance to diet-induced obesity

Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer

DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells

Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases

The family-wide structure and function of human dual-specificity protein phosphatases

Overexpression of dual-specificity phosphatases 4 and 13 attenuates transforming growth factor β1-induced migration and drug resistance in A549 cells in vitro

Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance

Dual-specificity phosphatases 13 and 27 as key switches in muscle stem cell transition from proliferation to differentiation

Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling

Inhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer

Exosomal miR-1228-5p down-regulates DUSP22 to promotes cell proliferation and migration in small cell lung cancer

The phosphatase PAC1 acts as a T cell suppressor and attenuates host antitumor immunity

Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1

Upregulation of DUSP6 impairs infectious bronchitis virus replication by negatively regulating ERK pathway and promoting apoptosis

Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis

Cdc14 Phosphatases Preferentially Dephosphorylate a Subset of Cyclin-dependent kinase (Cdk) Sites Containing Phosphoserine

MiR‐21‐5p/dual‐specificity phosphatase 8 signalling mediates the anti‐inflammatory effect of haem oxygenase‐1 in aged intracerebral haemorrhage rats

Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway

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