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Ultra-large library docking for discovering new chemotypes

Nature (London), 2019-02, Vol.566 (7743), p.224-229

2019

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Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia

Biological psychiatry (1969), 2017-01, Vol.81 (1), p.67-77

2017

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Current drug treatments targeting dopamine D3 receptor

Pharmacology & therapeutics (Oxford), 2016-09, Vol.165, p.164-177

2016

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Surgery as a Viable Alternative First-Line Treatment for Prolactinoma Patients. A Systematic Review and Meta-Analysis

The journal of clinical endocrinology and metabolism, 2020-03, Vol.105 (3), p.e32-e41

2020

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Dopamine Receptor Agonists for the Treatment of Early or Advanced Parkinson’s Disease

CNS drugs, 2010-11, Vol.24 (11), p.941-968

2010

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Recent Progress in Development of Dopamine Receptor Subtype-Selective Agents: Potential Therapeutics for Neurological and Psychiatric Disorders

Chemical reviews, 2007-01, Vol.107 (1), p.274-302

2007

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2-Phenylcyclopropylmethylamine Derivatives as Dopamine D 2 Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation

Journal of medicinal chemistry, 2021-12, Vol.64 (23), p.17239-17258

2021

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Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor

Nature communications, 2018-02, Vol.9 (1), p.674-17, Article 674

2018

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Computational modelling reveals contrasting effects on reinforcement learning and cognitive flexibility in stimulant use disorder and obsessive-compulsive disorder: remediating effects of dopaminergic D2/3 receptor agents

Psychopharmacology, 2019-08, Vol.236 (8), p.2337-2358

2019

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The physiology, signaling, and pharmacology of dopamine receptors

Pharmacological reviews, 2011-03, Vol.63 (1), p.182

2011

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D 4 dopamine receptor high-resolution structures enable the discovery of selective agonists

Science (American Association for the Advancement of Science), 2017-10, Vol.358 (6361), p.381-386

2017

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Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil

Brain (London, England : 1878), 2013-05, Vol.136 (Pt 5), p.1568-1577

2013

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Medication discovery for addiction: Translating the dopamine D3 receptor hypothesis

Biochemical pharmacology, 2012-10, Vol.84 (7), p.882-890

2012

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Dopaminergic Modulation of Risk-Based Decision Making

Neuropsychopharmacology (New York, N.Y.), 2009-02, Vol.34 (3), p.681-697

2009

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Dopamine Receptors Differentially Enhance Rule Coding in Primate Prefrontal Cortex Neurons

Neuron (Cambridge, Mass.), 2014-12, Vol.84 (6), p.1317-1328

2014

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Functionally Selective Dopamine D2/D3 Receptor Agonists Comprising an Enyne Moiety

Journal of medicinal chemistry, 2013-06, Vol.56 (12), p.5130-5141

2013

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Pramipexole, a Dopamine D2/D3 Receptor-Preferring Agonist, Prevents Experimental Autoimmune Encephalomyelitis Development in Mice

Molecular neurobiology, 2017-03, Vol.54 (2), p.1033-1045

2017

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Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5‑a]pyridine Substructure

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2908-2929

2017

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Bivalent dopamine agonists with co-operative binding and functional activities at dopamine D2 receptors, modulate aggregation and toxicity of alpha synuclein protein

Bioorganic & medicinal chemistry, 2023-01, Vol.78, p.117131-117131, Article 117131

2023

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Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D 3 Dopamine Receptor Agonist

Journal of medicinal chemistry, 2020-05, Vol.63 (10), p.5526-5567

2020

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Dopamine D1R Receptor Stimulation as a Mechanistic Pro-cognitive Target for Schizophrenia

Schizophrenia bulletin, 2022-01, Vol.48 (1), p.199-210

2022

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Advances and challenges in the search for D 2 and D 3 dopamine receptor-selective compounds

Cellular signalling, 2018-01, Vol.41, p.75

2018

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Reports of pathological gambling, hypersexuality, and compulsive shopping associated with dopamine receptor agonist drugs

JAMA internal medicine, 2014-12, Vol.174 (12), p.1930

2014

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Rationale and neurobiological effects of treatment with antipsychotics in patients with chronic schizophrenia considering dopamine supersensitivity

Behavioural brain research, 2021-04, Vol.403, p.113126, Article 113126

2021

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