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Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (44), p.27381-27387

2020

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Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial

The Lancet (British edition), 2018-03, Vol.391 (10123), p.850-859

2018

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Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome

Nature communications, 2019-04, Vol.10 (1), p.1916-1916, Article 1916

2019

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Bone regeneration in critical bone defects using three-dimensionally printed β-tricalcium phosphate/hydroxyapatite scaffolds is enhanced by coating scaffolds with either dipyridamole or BMP-2

Journal of biomedical materials research. Part B, Applied biomaterials, 2017-02, Vol.105 (2), p.366-375

2017

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Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways

Cell, 2019-11, Vol.179 (5), p.1160-1176.e24

2019

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Anti‐platelet therapy: phosphodiesterase inhibitors

British journal of clinical pharmacology, 2011-10, Vol.72 (4), p.634-646

2011

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Recent advances in drug repurposing using machine learning

Current opinion in chemical biology, 2021-12, Vol.65, p.74-84

2021

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Electrospun biodegradable elastic polyurethane scaffolds with dipyridamole release for small diameter vascular grafts

Acta biomaterialia, 2014-11, Vol.10 (11), p.4618-4628

2014

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Construction and study of blood purification membrane modified with PDE inhibitor: Investigation of antiplatelet activity and hemocompatibility

Colloids and surfaces, B, Biointerfaces, 2024-02, Vol.234, p.113725-113725, Article 113725

2024

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Targeting the adenosinergic system in restless legs syndrome: A pilot, "proof-of-concept" placebo-controlled TMS-based protocol

PloS one, 2024-05, Vol.19 (5), p.e0302829-e0302829

2024

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Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19

Antiviral research, 2022-10, Vol.206, p.105403-105403, Article 105403

2022

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Dipyridamole Enhances the Cytotoxicities of Trametinib against Colon Cancer Cells through Combined Targeting of HMGCS1 and MEK Pathway

Molecular cancer therapeutics, 2020-01, Vol.19 (1), p.135-146

2020

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Why Not Dipyridamole: a Review of Current Guidelines and Re-evaluation of Utility in the Modern Era

Cardiovascular drugs and therapy, 2022-06, Vol.36 (3), p.525-532

2022

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Engineering 3D Printed Bioceramic Scaffolds to Reconstruct Critical-Sized Calvaria Defects in a Skeletally Immature Pig Model

Plastic and reconstructive surgery (1963), 2023-08, Vol.152 (2), p.270e

2023

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Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines

Biochemical pharmacology, 2023-01, Vol.207, p.115376-115376, Article 115376

2023

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The Impact of Dipyridamole on Disease-Associated Microglia Phenotypic Transformation in White Matter Lesions Induced by Chronic Cerebral Hypoperfusion

Neurochemical research, 2024-03, Vol.49 (3), p.744-757

2024

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Repair of Critical‐Sized Long Bone Defects Using Dipyridamole‐Augmented 3D‐Printed Bioactive Ceramic Scaffolds

Journal of orthopaedic research, 2019-12, Vol.37 (12), p.2499-2507

2019

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OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues

Cancer research (Chicago, Ill.), 2017-04, Vol.77 (8), p.2102-2111

2017

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Ticagrelor Inhibits Adenosine Uptake In Vitro and Enhances Adenosine-Mediated Hyperemia Responses in a Canine Model

Journal of cardiovascular pharmacology and therapeutics, 2012-06, Vol.17 (2), p.164-172

2012

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Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study

International journal of molecular sciences, 2022-03, Vol.23 (7), p.3456

2022

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Protective efficacy of phosphodiesterase-1 inhibition against alpha-synuclein toxicity revealed by compound screening in LUHMES cells

Scientific reports, 2017-09, Vol.7 (1), p.11469-15, Article 11469

2017

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Effects of cardiovascular medications on primary patency of hemodialysis arteriovenous fistula

Scientific reports, 2020-07, Vol.10 (1), p.12135, Article 12135

2020

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An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer

Molecular metabolism (Germany), 2019-07, Vol.25, p.119-130

2019

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Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4)

Biochemical pharmacology, 2013-12, Vol.86 (11), p.1531-1540

2013

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Discovery of Dipyridamole Analogues with Enhanced Metabolic Stability for the Treatment of Idiopathic Pulmonary Fibrosis

Molecules (Basel, Switzerland), 2022-05, Vol.27 (11), p.3452

2022

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Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial

Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome

Bone regeneration in critical bone defects using three-dimensionally printed β-tricalcium phosphate/hydroxyapatite scaffolds is enhanced by coating scaffolds with either dipyridamole or BMP-2

Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways

Anti‐platelet therapy: phosphodiesterase inhibitors

Recent advances in drug repurposing using machine learning

Electrospun biodegradable elastic polyurethane scaffolds with dipyridamole release for small diameter vascular grafts

Construction and study of blood purification membrane modified with PDE inhibitor: Investigation of antiplatelet activity and hemocompatibility

Targeting the adenosinergic system in restless legs syndrome: A pilot, "proof-of-concept" placebo-controlled TMS-based protocol

Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19

Dipyridamole Enhances the Cytotoxicities of Trametinib against Colon Cancer Cells through Combined Targeting of HMGCS1 and MEK Pathway

Why Not Dipyridamole: a Review of Current Guidelines and Re-evaluation of Utility in the Modern Era

Engineering 3D Printed Bioceramic Scaffolds to Reconstruct Critical-Sized Calvaria Defects in a Skeletally Immature Pig Model

Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines

The Impact of Dipyridamole on Disease-Associated Microglia Phenotypic Transformation in White Matter Lesions Induced by Chronic Cerebral Hypoperfusion

Repair of Critical‐Sized Long Bone Defects Using Dipyridamole‐Augmented 3D‐Printed Bioactive Ceramic Scaffolds

OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues

Ticagrelor Inhibits Adenosine Uptake In Vitro and Enhances Adenosine-Mediated Hyperemia Responses in a Canine Model

Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study

Protective efficacy of phosphodiesterase-1 inhibition against alpha-synuclein toxicity revealed by compound screening in LUHMES cells

Effects of cardiovascular medications on primary patency of hemodialysis arteriovenous fistula

An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer

Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4)

Discovery of Dipyridamole Analogues with Enhanced Metabolic Stability for the Treatment of Idiopathic Pulmonary Fibrosis

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