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Poly(trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

Biomaterials science, 2016-01, Vol.4 (1), p.9-24

Fukushima, K

2016

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Anti-inflammatory activity of edible brown alga Eisenia bicyclis and its constituents fucosterol and phlorotannins in LPS-stimulated RAW264.7 macrophages

Food and chemical toxicology, 2013-09, Vol.59, p.199-206

2013

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Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5‑Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA

Journal of medicinal chemistry, 2021-10, Vol.64 (20), p.15214-15249

2021

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Construction and activity evaluation of novel benzodioxane derivatives as dual-target antifungal inhibitors

European journal of medicinal chemistry, 2022-01, Vol.227, p.113950-113950, Article 113950

2022

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Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.13140-13158

2020

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Inflammation-Responsive Antioxidant Nanoparticles Based on a Polymeric Prodrug of Vanillin

Biomacromolecules, 2013-05, Vol.14 (5), p.1618-1626

2013

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H2O2-triggered bubble generating antioxidant polymeric nanoparticles as ischemia/reperfusion targeted nanotheranostics

Biomaterials, 2016-04, Vol.85, p.195-203

2016

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Discovery of a series of 1,3,4-oxadiazole-2(3H)-thione derivatives containing piperazine skeleton as potential FAK inhibitors

Bioorganic & medicinal chemistry, 2017-05, Vol.25 (9), p.2593-2600

2017

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Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions

Molecules (Basel, Switzerland), 2017-11, Vol.22 (11), p.1881

2017

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Glucosylceramide synthase inhibitors prevent replication of SARS-CoV-2 and influenza virus

The Journal of biological chemistry, 2021-01, Vol.296, p.100470-100470, Article 100470

2021

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Synthesis, biological evaluation, and molecular docking studies of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan moiety as potential anticancer agents

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (21), p.6518-6524

2011

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Anti-inflammatory role of GM1 and other gangliosides on microglia

Journal of neuroinflammation, 2022-01, Vol.19 (1), p.9-9, Article 9

2022

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A surface-eroding poly(1,3-trimethylene carbonate) coating for fully biodegradable magnesium-based stent applications: Toward better biofunction, biodegradation and biocompatibility

Acta biomaterialia, 2013-11, Vol.9 (10), p.8678-8689

2013

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Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pK a: Antibacterial Agents with an Improved Safety Profile

Journal of medicinal chemistry, 2012-08, Vol.55 (15), p.6916-6933

2012

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The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents

Scientific reports, 2018-02, Vol.8 (1), p.2416-25, Article 2416

2018

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Tumor Acidity-Induced Sheddable Polyethylenimine-Poly(trimethylene carbonate)/DNA/Polyethylene Glycol-2,3-Dimethylmaleicanhydride Ternary Complex for Efficient and Safe Gene Delivery

ACS applied materials & interfaces, 2016-03, Vol.8 (10), p.6400-6410

2016

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Bioconjugation of Meldrum's acid activated furan: A detergent compatible assay for protein quantitation

Analytical biochemistry, 2023-02, Vol.662, p.114998-114998, Article 114998

2023

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Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement

Psychopharmacologia, 2011-05, Vol.215 (1), p.191-203

2011

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Cytotoxic Plakortides from the Brazilian Marine Sponge Plakortis angulospiculatus

Journal of natural products (Washington, D.C.), 2015-05, Vol.78 (5), p.996-1004

2015

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Short-Term Acyl-CoA:Cholesterol Acyltransferase Inhibition, Combined with Apoprotein A1 Overexpression, Promotes Atherosclerosis Inflammation Resolution in Mice

Molecular pharmacology, 2021-03, Vol.99 (3), p.175-183

2021

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Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments

European journal of medicinal chemistry, 2017-09, Vol.137, p.327-337

2017

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Biodegradable nanocomposite hydrogel structures with enhanced mechanical properties prepared by photo-crosslinking solutions of poly(trimethylene carbonate)–poly(ethylene glycol)–poly(trimethylene carbonate) macromonomers and nanoclay particles

Acta biomaterialia, 2012-12, Vol.8 (12), p.4233-4243

2012

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Synthesis and antioxidant activity of novel Mannich base of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (21), p.6763-6770

2013

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Synthesis and antitumor activity of 1,2,4-triazoles having 1,4-benzodioxan fragment as a novel class of potent methionine aminopeptidase type II inhibitors

Bioorganic & medicinal chemistry, 2011-10, Vol.19 (20), p.5948-5954

2011

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Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo

Nature communications, 2019-11, Vol.10 (1), p.5232-15, Article 5232

2019

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Poly(trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

Anti-inflammatory activity of edible brown alga Eisenia bicyclis and its constituents fucosterol and phlorotannins in LPS-stimulated RAW264.7 macrophages

Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5‑Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA

Construction and activity evaluation of novel benzodioxane derivatives as dual-target antifungal inhibitors

Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans

Inflammation-Responsive Antioxidant Nanoparticles Based on a Polymeric Prodrug of Vanillin

H2O2-triggered bubble generating antioxidant polymeric nanoparticles as ischemia/reperfusion targeted nanotheranostics

Discovery of a series of 1,3,4-oxadiazole-2(3H)-thione derivatives containing piperazine skeleton as potential FAK inhibitors

Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions

Glucosylceramide synthase inhibitors prevent replication of SARS-CoV-2 and influenza virus

Synthesis, biological evaluation, and molecular docking studies of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan moiety as potential anticancer agents

Anti-inflammatory role of GM1 and other gangliosides on microglia

A surface-eroding poly(1,3-trimethylene carbonate) coating for fully biodegradable magnesium-based stent applications: Toward better biofunction, biodegradation and biocompatibility

Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pK a: Antibacterial Agents with an Improved Safety Profile

The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents

Tumor Acidity-Induced Sheddable Polyethylenimine-Poly(trimethylene carbonate)/DNA/Polyethylene Glycol-2,3-Dimethylmaleicanhydride Ternary Complex for Efficient and Safe Gene Delivery

Bioconjugation of Meldrum's acid activated furan: A detergent compatible assay for protein quantitation

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement

Cytotoxic Plakortides from the Brazilian Marine Sponge Plakortis angulospiculatus

Short-Term Acyl-CoA:Cholesterol Acyltransferase Inhibition, Combined with Apoprotein A1 Overexpression, Promotes Atherosclerosis Inflammation Resolution in Mice

Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments

Biodegradable nanocomposite hydrogel structures with enhanced mechanical properties prepared by photo-crosslinking solutions of poly(trimethylene carbonate)–poly(ethylene glycol)–poly(trimethylene carbonate) macromonomers and nanoclay particles

Synthesis and antioxidant activity of novel Mannich base of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan

Synthesis and antitumor activity of 1,2,4-triazoles having 1,4-benzodioxan fragment as a novel class of potent methionine aminopeptidase type II inhibitors

Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo

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