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Molecular mechanisms in the pathogenesis of N-nitrosodimethylamine induced hepatic fibrosis

Cell death & disease, 2019-01, Vol.10 (1), p.18, Article 18

2019

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Design and optimization of cranberry extract loaded bile salt augmented liposomes for targeting of MCP-1/STAT3/VEGF signaling pathway in DMN-intoxicated liver in rats

Drug delivery, 2022-12, Vol.29 (1), p.427-439

2022

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Zinc Oxide Nanoparticles Ameliorate Dimethylnitrosamine-Induced Renal Toxicity in Rat

Applied biochemistry and biotechnology, 2022-04, Vol.194 (4), p.1699-1715

2022

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Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer

Molecular carcinogenesis, 2020-02, Vol.59 (2), p.215-226

2020

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Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats

Laboratory investigation, 2010-12, Vol.90 (12), p.1805-1816

2010

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Effect of Opisthorchis felineus infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian hamsters

Parasitology international, 2017-08, Vol.66 (4), p.458-463

2017

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Bovine milk-derived α-lactalbumin prevents hepatic fibrosis induced by dimethylnitrosamine via nitric oxide pathway in rats

Bioscience, biotechnology, and biochemistry, 2017-10, Vol.81 (10), p.1941-1947

2017

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Mismatch repair systems might facilitate the chromosomal recombination induced by N-nitrosodimethylamine, but not by N-nitrosodiethylamine, in Drosophila

Mutagenesis, 2020-03, Vol.35 (2), p.197-206

2020

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NDRG2 ameliorates hepatic fibrosis by inhibiting the TGF-β1/Smad pathway and altering the MMP2/TIMP2 ratio in rats

PloS one, 2011-11, Vol.6 (11), p.e27710

2011

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Mucin-producing hamster cholangiocarcinoma cell line, Ham-2, possesses the aggressive cancer phenotypes with liver and lung metastases

In vitro cellular & developmental biology. Animal, 2021-09, Vol.57 (8), p.825-834

2021

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N-acetylcysteine attenuates dimethylnitrosamine induced oxidative stress in rats

European journal of pharmacology, 2011-03, Vol.654 (2), p.181-186

2011

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Puerarin, isolated from Pueraria lobata (Willd.), protects against hepatotoxicity via specific inhibition of the TGF-β1/Smad signaling pathway, thereby leading to anti-fibrotic effect

Phytomedicine (Stuttgart), 2013-10, Vol.20 (13), p.1172-1179

2013

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Inhibition of high-mobility group box 1 expression by siRNA in rat hepatic stellate cells

World journal of gastroenterology : WJG, 2011-09, Vol.17 (36), p.4090-4098

2011

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Dicliptera Chinensis polysaccharides target TGF-β/Smad pathway and inhibit stellate cells activation in rats with dimethylnitrosamine-induced hepatic fibrosis

Cellular and molecular biology (Noisy-le-Grand, France), 2016-01, Vol.62 (1), p.99

2016

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Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosis

Journal of gastroenterology and hepatology, 2007-01, Vol.22 (1), p.99-111

2007

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Aromatic C-nitrosation of a bioactive molecule. Nitrosation of minoxidil

Organic & biomolecular chemistry, 2011-10, Vol.9 (22), p.7680-7684

2011

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Melatonin reduces dimethylnitrosamine-induced liver fibrosis in rats

Journal of pineal research, 2004-09, Vol.37 (2), p.78-84

2004

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Dietary exposure and urinary excretion of total N‐nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high‐ and low‐risk areas for esophageal cancer in southern China

International journal of cancer, 2002-11, Vol.102 (3), p.207-211

2002

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Preventive effect of fermented brown rice and rice bran on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in rats

International journal of oncology, 2004-12, Vol.25 (6), p.1809

2004

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Development of Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry Methods for Analysis of DNA Adducts of Formaldehyde and Their Application to Rats Treated with N-Nitrosodimethylamine or 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone

Chemical research in toxicology, 2007-08, Vol.20 (8), p.1141-1148

2007

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Isothiocyanates and freeze-dried strawberries as inhibitors of esophageal cancer

Toxicological sciences, 1999-12, Vol.52 (2), p.95-100

1999

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Toward a molecular equivalent dose: Use of the medaka model in comparative risk assessment

Comparative biochemistry and physiology. Toxicology & pharmacology, 2009-03, Vol.149 (2), p.141-151

2009

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PI3K-Akt/PKB signaling pathway in neutrophils and mononuclear cells exposed to N-nitrosodimethylamine

Journal of immunotoxicology, 2014-07, Vol.11 (3), p.231-237

2014

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Investigation of metabolite alteration in dimethylnitrosamine-induced liver fibrosis by GC-MS

Bioanalysis, 2013-01, Vol.5 (1), p.41-51

2013

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Role of ERK1/2 kinase in the expression of iNOS by NDMA in human neutrophils

Indian journal of experimental biology, 2013-01, Vol.51 (1), p.73-80

2013

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Molecular mechanisms in the pathogenesis of N-nitrosodimethylamine induced hepatic fibrosis

Design and optimization of cranberry extract loaded bile salt augmented liposomes for targeting of MCP-1/STAT3/VEGF signaling pathway in DMN-intoxicated liver in rats

Zinc Oxide Nanoparticles Ameliorate Dimethylnitrosamine-Induced Renal Toxicity in Rat

Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer

Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats

Effect of Opisthorchis felineus infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian hamsters

Bovine milk-derived α-lactalbumin prevents hepatic fibrosis induced by dimethylnitrosamine via nitric oxide pathway in rats

Mismatch repair systems might facilitate the chromosomal recombination induced by N-nitrosodimethylamine, but not by N-nitrosodiethylamine, in Drosophila

NDRG2 ameliorates hepatic fibrosis by inhibiting the TGF-β1/Smad pathway and altering the MMP2/TIMP2 ratio in rats

Mucin-producing hamster cholangiocarcinoma cell line, Ham-2, possesses the aggressive cancer phenotypes with liver and lung metastases

N-acetylcysteine attenuates dimethylnitrosamine induced oxidative stress in rats

Puerarin, isolated from Pueraria lobata (Willd.), protects against hepatotoxicity via specific inhibition of the TGF-β1/Smad signaling pathway, thereby leading to anti-fibrotic effect

Inhibition of high-mobility group box 1 expression by siRNA in rat hepatic stellate cells

Dicliptera Chinensis polysaccharides target TGF-β/Smad pathway and inhibit stellate cells activation in rats with dimethylnitrosamine-induced hepatic fibrosis

Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosis

Aromatic C-nitrosation of a bioactive molecule. Nitrosation of minoxidil

Melatonin reduces dimethylnitrosamine-induced liver fibrosis in rats

Dietary exposure and urinary excretion of total N‐nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high‐ and low‐risk areas for esophageal cancer in southern China

Preventive effect of fermented brown rice and rice bran on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in rats

Development of Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry Methods for Analysis of DNA Adducts of Formaldehyde and Their Application to Rats Treated with N-Nitrosodimethylamine or 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone

Isothiocyanates and freeze-dried strawberries as inhibitors of esophageal cancer

Toward a molecular equivalent dose: Use of the medaka model in comparative risk assessment

PI3K-Akt/PKB signaling pathway in neutrophils and mononuclear cells exposed to N-nitrosodimethylamine

Investigation of metabolite alteration in dimethylnitrosamine-induced liver fibrosis by GC-MS

Role of ERK1/2 kinase in the expression of iNOS by NDMA in human neutrophils

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