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Na + /K + -ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation

Molecules (Basel, Switzerland), 2021-03, Vol.26 (7), p.1905

2021

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Structures and characterization of digoxin- and bufalin-bound Na⁺,K⁺-ATPase compared with the ouabain-bound complex

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (6), p.1755-1760

2015

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Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms

Immunity (Cambridge, Mass.), 2014-04, Vol.40 (4), p.477-489

2014

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Evaluation of digoxin-boronate ester formation through in-capillary derivatisation-large volume sample stacking-capillary zone electrophoresis

Analytical methods, 2024-06, Vol.16 (23), p.3675-3683

2024

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Visual monitoring and optical recognition of digoxin by functionalized AuNPs and triangular AgNPs as efficient optical nano‐probes

Journal of molecular recognition, 2021-10, Vol.34 (10), p.e2917-n/a

2021

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A simple and sensitive LC-MS/MS method for therapeutic drug monitoring of digoxin in children

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2023-04, Vol.1221, p.123681-123681, Article 123681

2023

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21‑Benzylidene digoxin, a novel digoxin hemi-synthetic derivative, presents an anti-inflammatory activity through inhibition of edema, tumour necrosis factor alpha production, inducible nitric oxide synthase expression and leucocyte migration

International immunopharmacology, 2018-12, Vol.65, p.174-181

2018

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Structural Insights into the Interactions of Digoxin and Na + /K + -ATPase and Other Targets for the Inhibition of Cancer Cell Proliferation

Molecules (Basel, Switzerland), 2021-06, Vol.26 (12), p.3672

2021

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21-Benzylidene digoxin decreases proliferation by inhibiting the EGFR/ERK signaling pathway and induces apoptosis in HeLa cells

Steroids, 2020-03, Vol.155, p.108551-108551, Article 108551

2020

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Tetra-primer ARMS-PCR combined with GoldMag lateral flow assay for genotyping: simultaneous visual detection of both alleles

Nanoscale, 2020-05, Vol.12 (18), p.198-115

2020

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A sensitive method for digoxin determination using formate-adduct ion based on the effect of ionization enhancement in liquid chromatograph–mass spectrometer

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015-01, Vol.978-979, p.138-144

2015

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Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling

Scientific reports, 2018-01, Vol.8 (1), p.850-17, Article 850

2018

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Sensitive and robust LC-MS/MS analysis of digoxin in human plasma through optimization of in-source adduct formation

Bioanalysis, 2018-09, Vol.10 (17), p.1401-1411

2018

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An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs

Current topics in medicinal chemistry, 2016-08, Vol.16 (19), p.2156-2168

2016

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Ultrafast, universal and visual screening of dual genetically modified elements based on dual super PCR and a lateral flow biosensor

Food chemistry, 2019-05, Vol.279, p.246-251

2019

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Selectivity analyses of γ-benzylidene digoxin derivatives to different Na,K-ATPase α isoforms: a molecular docking approach

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.85-97

2018

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Pharmacokinetic interaction of green tea beverage containing cyclodextrins and high concentration catechins with P‐glycoprotein substrates in LLC‐GA5‐COL150 cells in vitro and in the small intestine of rats in vivo

Journal of pharmacy and pharmacology, 2017-12, Vol.69 (12), p.1736-1744

2017

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Ionotropin is the mammalian digoxin-like material (DLM). It is a phosphocholine ester of a steroid with 23 carbon atoms

Steroids, 2018-08, Vol.136, p.63-75

2018

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In vitro selection and characterization of deoxyribonucleic acid aptamers for digoxin

Analytica chimica acta, 2012-10, Vol.748, p.67-72

2012

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Na,K-ATPase activity modulates Src activation: A role for ATP/ADP ratio

Biochimica et biophysica acta, 2012-05, Vol.1818 (5), p.1269-1273

2012

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Glucitol-core containing gallotannins inhibit the formation of advanced glycation end-products mediated by their antioxidant potential

Food & function, 2016-05, Vol.7 (5), p.2213-2222

2016

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Cytotoxic Effects of Cardiac Glycosides in Colon Cancer Cells, Alone and in Combination with Standard Chemotherapeutic Drugs

Journal of natural products (Washington, D.C.), 2009, Vol.72 (11), p.1969-1974

2009

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Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein

Bioscience reports, 2016-04, Vol.36 (2)

2016

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Convallatoxin, the active cardiac glycoside of lily of the valley, minimally affects the ADVIA Centaur digoxin assay

Journal of clinical laboratory analysis, 2018-10, Vol.32 (8), p.e22583-n/a

2018

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Na + /K + -ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation

Structures and characterization of digoxin- and bufalin-bound Na⁺,K⁺-ATPase compared with the ouabain-bound complex

Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms

Evaluation of digoxin-boronate ester formation through in-capillary derivatisation-large volume sample stacking-capillary zone electrophoresis

Visual monitoring and optical recognition of digoxin by functionalized AuNPs and triangular AgNPs as efficient optical nano‐probes

A simple and sensitive LC-MS/MS method for therapeutic drug monitoring of digoxin in children

21‑Benzylidene digoxin, a novel digoxin hemi-synthetic derivative, presents an anti-inflammatory activity through inhibition of edema, tumour necrosis factor alpha production, inducible nitric oxide synthase expression and leucocyte migration

Structural Insights into the Interactions of Digoxin and Na + /K + -ATPase and Other Targets for the Inhibition of Cancer Cell Proliferation

21-Benzylidene digoxin decreases proliferation by inhibiting the EGFR/ERK signaling pathway and induces apoptosis in HeLa cells

Tetra-primer ARMS-PCR combined with GoldMag lateral flow assay for genotyping: simultaneous visual detection of both alleles

A sensitive method for digoxin determination using formate-adduct ion based on the effect of ionization enhancement in liquid chromatograph–mass spectrometer

Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling

Sensitive and robust LC-MS/MS analysis of digoxin in human plasma through optimization of in-source adduct formation

An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs

Ultrafast, universal and visual screening of dual genetically modified elements based on dual super PCR and a lateral flow biosensor

Selectivity analyses of γ-benzylidene digoxin derivatives to different Na,K-ATPase α isoforms: a molecular docking approach

21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctions

Pharmacokinetic interaction of green tea beverage containing cyclodextrins and high concentration catechins with P‐glycoprotein substrates in LLC‐GA5‐COL150 cells in vitro and in the small intestine of rats in vivo

Ionotropin is the mammalian digoxin-like material (DLM). It is a phosphocholine ester of a steroid with 23 carbon atoms

In vitro selection and characterization of deoxyribonucleic acid aptamers for digoxin

Na,K-ATPase activity modulates Src activation: A role for ATP/ADP ratio

Glucitol-core containing gallotannins inhibit the formation of advanced glycation end-products mediated by their antioxidant potential

Cytotoxic Effects of Cardiac Glycosides in Colon Cancer Cells, Alone and in Combination with Standard Chemotherapeutic Drugs

Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein

Convallatoxin, the active cardiac glycoside of lily of the valley, minimally affects the ADVIA Centaur digoxin assay

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