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Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index

PLoS medicine, 2004-12, Vol.1 (3), p.e62-e62

2004

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Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

PLoS biology, 2006-02, Vol.4 (2), p.e31-e31

2006

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Integrating genetic and network analysis to characterize genes related to mouse weight

PLoS genetics, 2006-08, Vol.2 (8), p.e130-e130

2006

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The limits of reductionism in medicine: could systems biology offer an alternative?

PLoS medicine, 2006-06, Vol.3 (6), p.e208-e208

2006

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An inflammatory cascade leading to hyperresistinemia in humans

PLoS medicine, 2004-11, Vol.1 (2), p.e45-e45

2004

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Changes in gene expression foreshadow diet-induced obesity in genetically identical mice

PLoS genetics, 2006-05, Vol.2 (5), p.e81-e81

2006

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Human immunodeficiency virus impairs reverse cholesterol transport from macrophages

PLoS biology, 2006-11, Vol.4 (11), p.e365-e365

2006

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Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

PLoS medicine, 2006-08, Vol.3 (8), p.e327-e327

2006

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Genetic regulation of unsaturated fatty acid composition in C. elegans

PLoS genetics, 2006-07, Vol.2 (7), p.e108-e108

2006

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Lipoprotein genotype and conserved pathway for exceptional longevity in humans

PLoS biology, 2006-04, Vol.4 (4), p.e113-e113

2006

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Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications

PLoS medicine, 2006-06, Vol.3 (6), p.e287

2006

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Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans

PLoS biology, 2005-02, Vol.3 (2), p.e53-e53

2005

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Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents

PLoS medicine, 2005-09, Vol.2 (9), p.e233-e233

2005

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Glucocorticoid receptor-dependent gene regulatory networks

PLoS genetics, 2005-08, Vol.1 (2), p.e16-e16

2005

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A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation

PLoS computational biology, 2005-09, Vol.1 (4), p.e36-e36

2005

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The clinical applications of a systems approach

PLoS medicine, 2006-07, Vol.3 (7), p.e209-e209

2006

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Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis

PLoS genetics, 2006-04, Vol.2 (4), p.e51-e51

2006

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Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy

PLoS medicine, 2005-02, Vol.2 (2), p.e45-e45

2005

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Effects of hypothalamic neurodegeneration on energy balance

PLoS biology, 2005-12, Vol.3 (12), p.e415-e415

2005

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Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis

PLoS medicine, 2006-02, Vol.3 (2), p.e22-e22

2006

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The uncoupling protein 1 gene (UCP1) is disrupted in the pig lineage: a genetic explanation for poor thermoregulation in piglets

PLoS genetics, 2006-08, Vol.2 (8), p.e129-e129

2006

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Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history

PLoS computational biology, 2006-01, Vol.2 (1), p.e9-e9

2006

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Critical role of gap junction coupled KATP channel activity for regulated insulin secretion

PLoS biology, 2006-02, Vol.4 (2), p.e26-e26

2006

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Ablation of PGC-1β Results in Defective Mitochondrial Activity, Thermogenesis, Hepatic Function, and Cardiac Performance

Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

Integrating genetic and network analysis to characterize genes related to mouse weight

A HIF1α Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas

The limits of reductionism in medicine: could systems biology offer an alternative?

An inflammatory cascade leading to hyperresistinemia in humans

Changes in gene expression foreshadow diet-induced obesity in genetically identical mice

Human immunodeficiency virus impairs reverse cholesterol transport from macrophages

Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

Genetic regulation of unsaturated fatty acid composition in C. elegans

Lipoprotein genotype and conserved pathway for exceptional longevity in humans

Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications

Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans

Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents

Glucocorticoid receptor-dependent gene regulatory networks

A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation

The clinical applications of a systems approach

Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis

Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy

Effects of hypothalamic neurodegeneration on energy balance

Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis

The uncoupling protein 1 gene (UCP1) is disrupted in the pig lineage: a genetic explanation for poor thermoregulation in piglets

Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history

Critical role of gap junction coupled KATP channel activity for regulated insulin secretion

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