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Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Science (American Association for the Advancement of Science), 2019-12, Vol.366 (6470), p.1255-1259

2019

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Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin

Cell chemical biology, 2017-12, Vol.24 (12), p.1479-1489.e4

2017

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Mechanism of Activation of AMPK by Cordycepin

Cell chemical biology, 2020-02, Vol.27 (2), p.214-222.e4

2020

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Paradigm Shift for Radical S‑Adenosyl‑l‑methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis

Journal of the American Chemical Society, 2018-07, Vol.140 (28), p.8634-8638

2018

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Structural insights into FTO’s catalytic mechanism for the demethylation of multiple RNA substrates

Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (8), p.2919-2924

2019

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PrimPol, an Archaic Primase/Polymerase Operating in Human Cells

Molecular cell, 2013-11, Vol.52 (4), p.541-553

2013

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Mechanistic investigation of B12-independent glycerol dehydratase and its activating enzyme GD-AE

Chemical communications (Cambridge, England), 2022-02, Vol.58 (16), p.2738-2741

2022

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Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig

Nature communications, 2016-10, Vol.7 (1), p.13052-13052, Article 13052

2016

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Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

Nature communications, 2019-12, Vol.10 (1), p.5564-11, Article 5564

2019

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Decreased Transition-State Analogue Affinity in Isotopically Heavy MTAN with Increased Catalysis

Biochemistry (Easton), 2023-10, Vol.62 (20), p.2928-2933

2023

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Residence Times for Femtomolar and Picomolar Inhibitors of MTANs

Biochemistry (Easton), 2023-06, Vol.62 (11), p.1776-1785

2023

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The crystal structure of a high affinity RNA stem-loop complexed with the bacteriophage MS2 capsid: further challenges in the modeling of ligand-RNA interactions

RNA (Cambridge), 2004-11, Vol.10 (11), p.1776-1782

2004

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Iron Fenton oxidation of 2′-deoxyguanosine in physiological bicarbonate buffer yields products consistent with the reactive oxygen species carbonate radical anion not the hydroxyl radical

Chemical communications (Cambridge, England), 2020-08, Vol.56 (68), p.9779-9782

2020

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Gas-Phase Conformations and Energetics of Protonated 2′‑Deoxyadenosine and Adenosine: IRMPD Action Spectroscopy and Theoretical Studies

The journal of physical chemistry. B, 2015-02, Vol.119 (7), p.2795-2805

2015

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Efficient labelling of enzymatically synthesized vinyl-modified DNA by an inverse-electron-demand Diels-Alder reaction

Chemical communications (Cambridge, England), 2014-09, Vol.50 (74), p.10827-10829

2014

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A natural cordycepin/chitosan complex hydrogel with outstanding self-healable and wound healing properties

International journal of biological macromolecules, 2019-08, Vol.134, p.91-99

2019

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The cyclopurine deoxynucleosides: DNA repair, biological effects, mechanistic insights, and unanswered questions

Free radical biology & medicine, 2017-06, Vol.107, p.90-100

Brooks, Philip J.

2017

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4'-Ethynyl-2-fluoro-2'-deoxyadenosine, MK-8591: a novel HIV-1 reverse transcriptase translocation inhibitor

Current opinion in HIV & AIDS, 2018-07, Vol.13 (4), p.294

2018

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Genotoxic C8-Arylamino-2′-deoxyadenosines Act as Latent Alkylating Agents to Induce DNA Interstrand Cross-Links

Journal of the American Chemical Society, 2021-11, Vol.143 (45), p.18960-18976

2021

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Repurposing potential of FDA‐approved and investigational drugs for COVID‐19 targeting SARS‐CoV‐2 spike and main protease and validation by machine learning algorithm

Chemical biology & drug design, 2021-04, Vol.97 (4), p.836-853

2021

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Aminyl Radical Generation via Tandem Norrish Type I Photocleavage, β‑Fragmentation: Independent Generation and Reactivity of the 2′-Deoxyadenosin- N6‑yl Radical

Journal of organic chemistry, 2017-04, Vol.82 (7), p.3571-3580

2017

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Flexizyme-catalyzed synthesis of 3'-aminoacyl-NH-tRNAs

Nucleic acids research, 2019-05, Vol.47 (9), p.e54

2019

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Cordycepin Isolated from Cordyceps militaris : Its Newly Discovered Herbicidal Property and Potential Plant-Based Novel Alternative to Glyphosate

Molecules (Basel, Switzerland), 2019-08, Vol.24 (16), p.2901

2019

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N 6 -methyladenine is incorporated into mammalian genome by DNA polymerase

Cell research, 2021-01, Vol.31 (1), p.94

2021

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Supramolecular Nanofibers and Hydrogels of Nucleopeptides

Angewandte Chemie (International ed.), 2011-09, Vol.50 (40), p.9365-9369

International ed. in English, 2011

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Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin

Mechanism of Activation of AMPK by Cordycepin

Paradigm Shift for Radical S‑Adenosyl‑l‑methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis

Structural insights into FTO’s catalytic mechanism for the demethylation of multiple RNA substrates

PrimPol, an Archaic Primase/Polymerase Operating in Human Cells

Mechanistic investigation of B12-independent glycerol dehydratase and its activating enzyme GD-AE

Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

Decreased Transition-State Analogue Affinity in Isotopically Heavy MTAN with Increased Catalysis

Residence Times for Femtomolar and Picomolar Inhibitors of MTANs

The crystal structure of a high affinity RNA stem-loop complexed with the bacteriophage MS2 capsid: further challenges in the modeling of ligand-RNA interactions

Iron Fenton oxidation of 2′-deoxyguanosine in physiological bicarbonate buffer yields products consistent with the reactive oxygen species carbonate radical anion not the hydroxyl radical

Gas-Phase Conformations and Energetics of Protonated 2′‑Deoxyadenosine and Adenosine: IRMPD Action Spectroscopy and Theoretical Studies

Efficient labelling of enzymatically synthesized vinyl-modified DNA by an inverse-electron-demand Diels-Alder reaction

A natural cordycepin/chitosan complex hydrogel with outstanding self-healable and wound healing properties

The cyclopurine deoxynucleosides: DNA repair, biological effects, mechanistic insights, and unanswered questions

4'-Ethynyl-2-fluoro-2'-deoxyadenosine, MK-8591: a novel HIV-1 reverse transcriptase translocation inhibitor

Genotoxic C8-Arylamino-2′-deoxyadenosines Act as Latent Alkylating Agents to Induce DNA Interstrand Cross-Links

Repurposing potential of FDA‐approved and investigational drugs for COVID‐19 targeting SARS‐CoV‐2 spike and main protease and validation by machine learning algorithm

Aminyl Radical Generation via Tandem Norrish Type I Photocleavage, β‑Fragmentation: Independent Generation and Reactivity of the 2′-Deoxyadenosin- N6‑yl Radical

Flexizyme-catalyzed synthesis of 3'-aminoacyl-NH-tRNAs

Cordycepin Isolated from Cordyceps militaris : Its Newly Discovered Herbicidal Property and Potential Plant-Based Novel Alternative to Glyphosate

N 6 -methyladenine is incorporated into mammalian genome by DNA polymerase

Supramolecular Nanofibers and Hydrogels of Nucleopeptides

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