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Helicases from All Domains of Life

Tuteja, Renu

1, 2018

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Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy

Cell chemical biology, 2017-09, Vol.24 (9), p.1101-1119

2017

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Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM

Nature communications, 2024-08, Vol.15 (1), p.7003-13

2024

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FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

Nature communications, 2019-05, Vol.10 (1), p.2253-2253, Article 2253

2019

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R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response

Nature (London), 2023-01, Vol.613 (7942), p.187-194

2023

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G-quadruplexes and helicases

Nucleic acids research, 2016-03, Vol.44 (5), p.1989-2006

2016

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The mechanism of eukaryotic CMG helicase activation

Nature (London), 2018-03, Vol.555 (7695), p.265-268

2018

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Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Nature communications, 2018-02, Vol.9 (1), p.533-14, Article 533

2018

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RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

Nature structural & molecular biology, 2020-05, Vol.27 (5), p.424-437

2020

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ChrII-Encoded DNA Helicase: A Preliminary Study

Protein and peptide letters, 2023, Vol.30 (1), p.35-43

2023

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RAD51 bypasses the CMG helicase to promote replication fork reversal

Science (American Association for the Advancement of Science), 2023-04, Vol.380 (6643), p.382-387

2023

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Linear mitochondrial DNA is rapidly degraded by components of the replication machinery

Nature communications, 2018-04, Vol.9 (1), p.1727-11, Article 1727

2018

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Harmful R-loops are prevented via different cell cycle-specific mechanisms

Nature communications, 2021-07, Vol.12 (1), p.4451-4451, Article 4451

2021

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OsSUV3 dual helicase functions in salinity stress tolerance by maintaining photosynthesis and antioxidant machinery in rice (Oryza sativa L. cv. IR64)

The Plant journal : for cell and molecular biology, 2013-10, Vol.76 (1), p.115-127

2013

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BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

Genes & development, 2011-02, Vol.25 (4), p.350-362

2011

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Structural basis of TFIIH activation for nucleotide excision repair

Nature communications, 2019-06, Vol.10 (1), p.2885-9, Article 2885

2019

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Multiple rereads of single proteins at single-amino acid resolution using nanopores

Science (American Association for the Advancement of Science), 2021-12, Vol.374 (6574), p.1509-1513

2021

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Frequent nonhomologous replacement of replicative helicase loaders by viruses in Vibrionaceae

Proceedings of the National Academy of Sciences - PNAS, 2024-05, Vol.121 (19), p.e2317954121

2024

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The HIRAN domain of helicase-like transcription factor positions the DNA translocase motor to drive efficient DNA fork regression

The Journal of biological chemistry, 2018-06, Vol.293 (22), p.8484-8494

2018

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DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination

The Journal of biological chemistry, 2015-09, Vol.290 (38), p.22931-22938

Cejka, Petr

2015

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Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication

The EMBO journal, 2020-09, Vol.39 (18), p.e104185-n/a

2020

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The translocon protein FtsHi1 is an ATP‐dependent DNA/RNA helicase that prevents R‐loop accumulation in chloroplasts

The New phytologist, 2024-03, Vol.241 (5), p.2209-2226

2024

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Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge

Nature communications, 2024-07, Vol.15 (1), p.6104-13, Article 6104

2024

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A long noncoding RNA protects the heart from pathological hypertrophy

Nature (London), 2014-10, Vol.514 (7520), p.102-106

2014

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Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner

Science (American Association for the Advancement of Science), 2021-06, Vol.372 (6549), p.eabf6548-eabf6548

2021

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Helicases from All Domains of Life

Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy

Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM

FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response

G-quadruplexes and helicases

The mechanism of eukaryotic CMG helicase activation

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

ChrII-Encoded DNA Helicase: A Preliminary Study

RAD51 bypasses the CMG helicase to promote replication fork reversal

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery

Harmful R-loops are prevented via different cell cycle-specific mechanisms

OsSUV3 dual helicase functions in salinity stress tolerance by maintaining photosynthesis and antioxidant machinery in rice (Oryza sativa L. cv. IR64)

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

Structural basis of TFIIH activation for nucleotide excision repair

Multiple rereads of single proteins at single-amino acid resolution using nanopores

Frequent nonhomologous replacement of replicative helicase loaders by viruses in Vibrionaceae

The HIRAN domain of helicase-like transcription factor positions the DNA translocase motor to drive efficient DNA fork regression

DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination

Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication

The translocon protein FtsHi1 is an ATP‐dependent DNA/RNA helicase that prevents R‐loop accumulation in chloroplasts

Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge

A long noncoding RNA protects the heart from pathological hypertrophy

Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner

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