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Drugs as CYP3A Probes, Inducers, and Inhibitors

Drug metabolism reviews, 2007-01, Vol.39 (4), p.699-721

2007

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Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities

Drug metabolism and disposition, 2012-01, Vol.40 (1), p.83-92

2012

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Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro

British journal of clinical pharmacology, 2018-03, Vol.84 (3), p.510-519

2018

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Mechanisms of evolved herbicide resistance

The Journal of biological chemistry, 2020-07, Vol.295 (30), p.10307-10330

2020

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Boosting 11-oxo-β-amyrin and glycyrrhetinic acid synthesis in Saccharomyces cerevisiae via pairing novel oxidation and reduction system from legume plants

Metabolic engineering, 2018-01, Vol.45, p.43-50

2018

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Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

Drug metabolism and disposition, 2003-04, Vol.31 (4), p.421-431

2003

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Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy

PloS one, 2013-12, Vol.8 (12), p.e82562-e82562

2013

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Engineering yeast for high-level production of stilbenoid antioxidants

Scientific reports, 2016-11, Vol.6 (1), p.36827-36827, Article 36827

2016

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Expression and characterization of CYP4V2 as a fatty acid omega-hydroxylase

Drug metabolism and disposition, 2009-11, Vol.37 (11), p.2119-2122

2009

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Functional expression of eukaryotic cytochrome P450s in yeast

Biotechnology and bioengineering, 2021-03, Vol.118 (3), p.1050-1065

2021

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Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes

Drug metabolism and disposition, 2007-09, Vol.35 (9), p.1687-1693

2007

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A cytochrome P450 regulates a domestication trait in cultivated tomato

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (42), p.17125-17130

2013

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Overexpression of the brassinosteroid biosynthetic gene DWF4 in Brassica napus simultaneously increases seed yield and stress tolerance

Scientific reports, 2016-06, Vol.6 (1), p.28298-28298, Article 28298

2016

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Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells

Drug metabolism and disposition, 2010-03, Vol.38 (3), p.516-525

2010

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Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

PloS one, 2018-01, Vol.13 (1), p.e0191295

2018

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Epoxyeicosatrienoic Acids Regulate Macrophage Polarization and Prevent LPS-Induced Cardiac Dysfunction

Journal of cellular physiology, 2015-09, Vol.230 (9), p.2108-2119

2015

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Absolute quantification and differential expression of drug transporters, cytochrome P450 enzymes, and UDP-glucuronosyltransferases in cultured primary human hepatocytes

Drug metabolism and disposition, 2012-01, Vol.40 (1), p.93-103

2012

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Isoform-specific regulation of cytochromes P450 expression by estradiol and progesterone

Drug metabolism and disposition, 2013-02, Vol.41 (2), p.263-269

2013

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Expression of clinically relevant drug‐metabolizing enzymes along the human intestine and their correlation to drug transporters and nuclear receptors: An intra‐subject analysis

Basic & clinical pharmacology & toxicology, 2019-03, Vol.124 (3), p.245-255

2019

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Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats

Journal of ethnopharmacology, 2013-04, Vol.146 (3), p.734-743

2013

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Age-related changes in hepatic expression and activity of cytochrome P450 in male rats

Archives of toxicology, 2010-12, Vol.84 (12), p.939-946

2010

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A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Pharmaceutical research, 2006-03, Vol.23 (3), p.521-532

2006

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Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study

Toxicology in vitro, 2019-10, Vol.60, p.212-228

2019

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Intestinal Drug Transporter Expression and the Impact of Grapefruit Juice in Humans

Clinical pharmacology and therapeutics, 2007-03, Vol.81 (3), p.362-370

2007

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Inhibition and induction of human cytochrome P450 enzymes: current status

Archives of toxicology, 2008-10, Vol.82 (10), p.667-715

2008

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Drugs as CYP3A Probes, Inducers, and Inhibitors

Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities

Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro

Mechanisms of evolved herbicide resistance

Boosting 11-oxo-β-amyrin and glycyrrhetinic acid synthesis in Saccharomyces cerevisiae via pairing novel oxidation and reduction system from legume plants

Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy

Engineering yeast for high-level production of stilbenoid antioxidants

Expression and characterization of CYP4V2 as a fatty acid omega-hydroxylase

Functional expression of eukaryotic cytochrome P450s in yeast

Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes

A cytochrome P450 regulates a domestication trait in cultivated tomato

Overexpression of the brassinosteroid biosynthetic gene DWF4 in Brassica napus simultaneously increases seed yield and stress tolerance

Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells

Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma

Epoxyeicosatrienoic Acids Regulate Macrophage Polarization and Prevent LPS-Induced Cardiac Dysfunction

Absolute quantification and differential expression of drug transporters, cytochrome P450 enzymes, and UDP-glucuronosyltransferases in cultured primary human hepatocytes

Isoform-specific regulation of cytochromes P450 expression by estradiol and progesterone

Expression of clinically relevant drug‐metabolizing enzymes along the human intestine and their correlation to drug transporters and nuclear receptors: An intra‐subject analysis

Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats

Age-related changes in hepatic expression and activity of cytochrome P450 in male rats

A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study

Intestinal Drug Transporter Expression and the Impact of Grapefruit Juice in Humans

Inhibition and induction of human cytochrome P450 enzymes: current status

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